Focus on: Neurotransmitter systems

Alcohol Research and Health

Volumn 34, Issue 1, 2011, Pages 106-120

  Valenzuela, C Fernando ^a   Puglia, Michael P ^a   Zucca, Stefano ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol syndrome disorders; Amino acids; Animal models; Biogenic amines; Central nervous system; Developmental disorders; Neurotransmitter systems; Pregnancy

Indexed keywords

4 AMINOBUTYRIC ACID; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BIOGENIC AMINE;

ADVERSE EFFECTS; ANIMAL; DRINKING BEHAVIOR; DRUG EFFECTS; FEMALE; FETAL ALCOHOL SPECTRUM DISORDERS; HUMAN; METABOLISM; NERVE CELL PLASTICITY; PHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE;

ALCOHOL DRINKING; ANIMALS; BIOGENIC AMINES; FEMALE; FETAL ALCOHOL SPECTRUM DISORDERS; GAMMA-AMINOBUTYRIC ACID; HUMANS; NEURONAL PLASTICITY; NEUROTRANSMITTER AGENTS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 79960990453     PISSN: 15357414     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (86)

1. Alati, R.; Al Mamun, A.; Williams, G.M.; et al. In utero alcohol exposure and prediction of alcohol disorders in early adulthood: A birth cohort study. Archives of General Psychiatry 63:1009-1016, 2006. PMID: 16953003
2. Baer, J.S.; Sampson, P.D.; Barr, H.M.; et al. A 21year longitudinal analysis of the effects of prenatal alcohol exposure on young adult drinking. Archives of General Psychiatry 60:377-385, 2003. PMID: 12695315
3. Bailey, C.D.; Brien, J.F.; and Reynolds, J.N. Chronic prenatal ethanol exposure increases GABA(A) receptor subunit protein expression in the adult guinea pig cerebral cortex. Journal of Neuroscience 21:4381-4389, 2001. PMID: 11404424
4. Bailey, C.D.; Brien, J.F.; and Reynolds, J.N. Chronic prenatal ethanol exposure alters the proportion of GABAergic neurons in layers II/III of the adult guinea pig somatosensory cortex. Neurotoxicology and Teratology 26:59-63, 2004. PMID: 15001214
5. Barbier, E.; Houchi, H.; Warnault, V.; et al. Effects of prenatal and postnatal maternal ethanol on offspring response to alcohol and psychostimulants in Long Evans rats. Neuroscience 161:427-440, 2009. PMID: 19348874
6. Barbier, E.; Pierrefiche, O.; Vaudry, D.; et al. Longterm alterations in vulnerability to addiction to drugs of abuse and in brain gene expression after early life ethanol exposure. Neuropharmacology 55:1199-1211, 2008. PMID: 18713641
7. Bassell, G.J., and Warren, S.T. Fragile X syndrome: Loss of local mRNA regulation alters synaptic development and function. Neuron 60:201-214, 2008. PMID: 18957214
8. Bell, S.H.; Stade, B.; Reynolds, J.N.; et al. The remarkably high prevalence of epilepsy and seizure history in fetal alcohol spectrum disorders. Alcoholism: Clinical and Experimental Research 34:1084-1089, 2010. PMID: 20374205
9. BenAri, Y. Excitatory actions of GABA during development: The nature of the nurture. Nature Reviews Neuroscience 3:728-739, 2002. PMID: 12209121
10. BenAri, Y. Neuroarchaeology: Presymptomatic architecture and signature of neurological disorders. Trends in Neurosciences 31:626-636, 2008. PMID: 18951639
11. Berman, R.F., and Hannigan, J.H. Effects of prenatal alcohol exposure on the hippocampus: Spatial behavior, electrophysiology, and neuroanatomy. Hippocampus 10:94-110, 2000. PMID: 10706221
12. Bonthius, D.J.; Pantazis, N.J.; Karacay, B.; et al. Alcohol exposure during the brain growth spurt promotes hippocampal seizures, rapid kindling, and spreading depression. Alcoholism: Clinical and Experimental Research 25:734-745, 2001. PMID: 11371723
13. Caldwell, K.K.; Sheema, S.; Paz, R.D.; et al. Fetal alcohol spectrum disorderassociated depression: Evidence for reductions in the levels of brainderived neurotrophic factor in a mouse model. Pharmacology, Biochemistry, and Behavior 90:614-624, 2008. PMID: 18558427
14. Castrén, E., and Rantamäki, T. Neurotrophins in depression and antidepressant effects. Novartis Foundation Symposium 289:43-52; discussion 53-59, 87-93, 2008. PMID: 18497094
15. Catania, M.V.; D'Antoni, S.; Bonaccorso, C.M.; et al. Group I metabotropic glutamate receptors: A role in neurodevelopmental disorders? Molecular Neurobiology 35:298-307, 2007. PMID: 17917118
16. Cline, H., and Haas, K. The regulation of dendritic arbor development and plasticity by glutamatergic synaptic input: A review of the synaptotrophic hypothesis. Journal of Physiology 586:1509-1517, 2008. PMID: 18202093
17. Costa, E.T.; Savage, D.D.; and Valenzuela, C.F. A review of the effects of prenatal or early postnatal ethanol exposure on brain ligandgated ion channels. Alcoholism: Clinical and Experimental Research 24:706-715, 2000. PMID: 10832913
18. Cuzon, V.C.; Yeh, P.W.; Yanagawa, Y.; et al. Ethanol consumption during early pregnancy alters the disposition of tangentially migrating GABAergic interneurons in the fetal cortex. Journal of Neuroscience 28:1854-1864, 2008. PMID: 18287502
19. Dettmer, T.S.; Barnes, A.; Iqbal, U.; et al. Chronic prenatal ethanol exposure alters ionotropic glutamate receptor subunit protein levels in the adult guinea pig cerebral cortex. Alcoholism: Clinical and Experimental Research 27:677-681, 2003. PMID: 12711930
20. Druse, M.; Tajuddin, N.F.; Gillespie, R.A.; and Le, P. Signaling pathways involved with serotonin1A agonistmediated neuroprotection against ethanol induced apoptosis of fetal rhombencephalic neurons. Brain Research. Developmental Brain Research 159:18-28, 2005. PMID: 16081165
21. Frederick, A.L., and Stanwood, G.D. Drugs, biogenic amine targets and the developing brain. Developmental Neuroscience 31:7-22, 2009. PMID: 19372683
22. Gaiarsa, J.L. Plasticity of GABAergic synapses in the neonatal rat hippocampus. Journal of Cellular and Molecular Medicine 8:31-37, 2004. PMID: 15090258
23. Galindo, R.; Frausto, S.; Wolff, C.; et al. Prenatal ethanol exposure reduces mGluR5 receptor number and function in the dentate gyrus of adult offspring. Alcoholism: Clinical and Experimental Research 28:1587-1597, 2004. PMID: 15597093
24. Galindo, R.; Zamudio, P.A.; and Valenzuela, C.F. Alcohol is a potent stimulant of immature neuronal networks: Implications for fetal alcohol spectrum disorder. Journal of Neurochemistry 94:1500-1511, 2005. PMID: 16000153
25. Goodlett, C.R.; Horn, K.H.; and Zhou, F.C. Alcohol teratogenesis: Mechanisms of damage and strategies for intervention. Experimental Biology and Medicine (Maywood) 230:394-406, 2005. PMID: 15956769
26. Green, J.T. The effects of ethanol on the developing cerebellum and eyeblink classical conditioning. Cerebellum 3:178-187, 2004. PMID: 15543808
27. Hanse, E.; Taira, T.; Lauri, S.; and Groc, L. Glutamate synapse in developing brain: An integrative perspective beyond the silent state. Trends in Neurosciences 32:532-537, 2009. PMID: 19733923
28. Hofmann, C.E.; Ellis, L.; Yu, W.K.; and Weinberg, J. Hypothalamicpituitaryadrenal responses to 5HT1A and 5HT2A/C agonists are differentially altered in female and male rats prenatally exposed to ethanol. Alcoholism: Clinical and Experimental Research 31:345-355, 2007. PMID: 17250628
29. Honse, Y.; Nixon, K.M.; Browning, M.D.; and Leslie, S.W. Cell surface expression of NR1 splice variants and NR2 subunits is modified by prenatal ethanol exposure. Neuroscience 122:689-698, 2003. PMID: 14622912
30. Hsiao, S.H.; Acevedo, J.L.; DuBois, D.W.; et al. Early postnatal ethanol intubation blunts GABA(A) receptor upregulation and modifies 3alphahydroxy5alphapregnan20one sensitivity in rat MS/DB neurons. Brain Research. Developmental Brain Research 130:25-40, 2001. PMID: 11557091
31. Hsiao, S.H., and Frye, G.D. AMPA receptors on developing medial septum/diagonal band neurons are sensitive to early postnatal bingelike ethanol exposure. Brain Research. Developmental Brain Research 142:89-99, 2003. PMID: 12694947
32. Hsiao, S.H.; West, J.R.; Mahoney, J.C.; and Frye, G.D. Postnatal ethanol exposure blunts upregulation of GABAA receptor currents in Purkinje neurons. Brain Research 832:124-135, 1999. PMID: 10375658
33. Ikonomidou, C.; Bittigau, P.; Ishimaru, M.J.; et al. Ethanolinduced apoptotic neurodegeneration and fetal alcohol syndrome. Science 287:1056-1060, 2000. PMID: 10669420
34. Incerti, M.; Vink, J.; Roberson, R.; et al. Reversal of alcoholinduced learning deficits in the young adult in a model of fetal alcohol syndrome. Obstetrics and Gynecology 115:350-356, 2010. PMID: 20093910
35. Iqbal, U.; Brien, J.F.; Kapoor, A.; et al. Chronic prenatal ethanol exposure increases glucocorticoidinduced glutamate release in the hippocampus of the nearterm foetal guinea pig. Journal of Neuroendocrinology 18:826-834, 2006. PMID: 17026532
36. Izumi, Y.; Kitabayashi, R.; Funatsu, M.; et al. A single day of ethanol exposure during development has persistent effects on bidirectional plasticity, NmethylDaspartate receptor function and ethanol sensitivity. Neuroscience 136:269-279, 2005. PMID: 16181739
37. Kervern, M.; Dubois, C.; Naassila, M.; et al. Perinatal alcohol exposure in rat induces longterm depression of respiration after episodic hypoxia. American Journal of Respiratory and Critical Care Medicine 179:608-614, 2009. PMID: 19106308
38. Kinney, H.C.; Randall, L.L.; Sleeper, L.A.; et al. Serotonergic brainstem abnormalities in Northern Plains Indians with the sudden infant death syndrome. Journal of Neuropathology and Experimental Neurology 62:1178-1191, 2003. PMID: 14656075
39. Kraemer, G.W.; Moore, C.F.; Newman, T.K.; et al. Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbichypothalamicpituitaryadrenal axis regulation in monkeys. Biological Psychiatry 63:317-324, 2008. PMID: 17884019
40. Lee, S.; Choi, I.; Kang, S.; and Rivier, C. Role of various neurotransmitters in mediating the longterm endocrine consequences of prenatal alcohol exposure. Annals of the New York Academy of Sciences 1144:176-188, 2008. PMID: 19076376
41. Lewis, B.; Wellmann, K.A.; and Barron, S. Agmatine reduces balance deficits in a rat model of third trimester bingelike ethanol exposure. Pharmacology, Biochemistry, and Behavior 88:114-121, 2007. PMID: 17714770
42. Mameli, M., and Valenzuela, C.F. Alcohol increases efficacy of immature synapses in a neurosteroiddependent manner. European Journal of Neuroscience 23:835-839, 2006. PMID: 16487164
43. Mameli, M.; Zamudio, P.A.; Carta, M.; and Valenzuela, C.F. Developmentally regulated actions of alcohol on hippocampal glutamatergic transmission. Journal of Neuroscience 25:8027-8036, 2005. PMID: 16135760
44. Manent, J.B., and Represa, A. Neurotransmitters and brain maturation: Early paracrine actions of GABA and glutamate modulate neuronal migration. Neuroscientist 13:268-279, 2007. PMID: 17519369
45. Margret, C.P.; Li, C.X.; Chappell, T.D.; et al. Prenatal alcohol exposure delays the development of the cortical barrel field in neonatal rats. Experimental Brain Research 172:1-13, 2006. PMID: 16506013
46. Martinowich, K., and Lu, B. Interaction between BDNF and serotonin: Role in mood disorders. Neuropsychopharmacology 33:73-83, 2008. PMID: 17882234
47. Matta, S.G., and Elberger, A.J. Combined exposure to nicotine and ethanol throughout full gestation results in enhanced acquisition of nicotine selfadministration in young adult rat offspring. Psychopharmacology (Berl) 193:199-213, 2007. PMID: 17404712
48. Medina, A.E., and Krahe, T.E. Neocortical plasticity deficits in fetal alcohol spectrum disorders: Lessons from barrel and visual cortex. Journal of Neuroscience Research 86:256-263, 2008. PMID: 17671993
49. Middleton, F.A.; Carrierfenster, K.; Mooney, S.M.; and Youngentob, S.L. Gestational ethanol exposure alters the behavioral response to ethanol odor and the expression of neurotransmission genes in the olfactory bulb of adolescent rats. Brain Research 1252:105-116, 2009. PMID: 19063871
50. Miller, M.W. Effect of prenatal exposure to ethanol on glutamate and GABA immunoreactivity in macaque somatosensory and motor cortices: Critical timing of exposure. Neuroscience 138:97-107, 2006. PMID: 16427209
51. Mohajerani, M.H., and Cherubini, E. Role of giant depolarizing potentials in shaping synaptic currents in the developing hippocampus. Critical Reviews in Neurobiology 18:13-23, 2006. PMID: 17725505
52. Moody, W.J., and Bosma, M.M. Ion channel development, spontaneous activity, and activitydependent development in nerve and muscle cells. Physiology Reviews 85:883-941, 2005. PMID: 15987798
53. Naassila, M., and Daoust, M. Effect of prenatal and postnatal ethanol exposure on the developmental profile of mRNAs encoding NMDA receptor subunits in rat hippocampus. Journal of Neurochemistry 80:850-860, 2002. PMID: 11948249
54. Netzeband, J.G.; Schneeloch, J.R.; Trotter, C.; et al. Chronic ethanol treatment and withdrawal alter ACPDevoked calcium signals in developing Purkinje neurons. Alcoholism: Clinical and Experimental Research 26:386-393, 2002. PMID: 11923593
55. Noble, E.P., and Ritchie, T. Prenatal ethanol exposure reduces the effects of excitatory amino acids in the rat hippocampus. Life Sciences 45:803-810, 1989. PMID: 254932
56. O'Connor, M. J. and Paley, B. The relationship of prenatal alcohol exposure and the postnatal environment to child depressive symptoms. Journal of Pediatric Psychology 31:50-64, 2006. PMID: 15802607
57. Pirker, S.; Schwarzer, C.; Wieselthaler, A.; et al. GABA(A) receptors: Immunocytochemical distribution of 13 subunits in the adult rat brain. Neuroscience 101:815-850, 2000. PMID: 11113332
58. Puglia, M.P., and Valenzuela, C.F. AMPARmediated synaptic transmission in the CA1 hippocampal region of neonatal rats: Unexpected resistance to repeated ethanol exposure. Alcohol 43:619-625, 2009. PMID: 20004339
59. Puglia, M.P., and Valenzuela, C.F. Ethanol acutely inhibits ionotropic glutamate receptormediated responses and longterm potentiation in the developing CA1 hippocampus. Alcoholism: Clinical and Experimental Research 34:594-606, 2010a. PMID: 20102565
60. Puglia, M.P., and Valenzuela, C.F. Repeated third trimesterequivalent ethanol exposure inhibits longterm potentiation in the hippocampal CA1 region of neonatal rats. Alcohol 44:283-290, 2010b. PMID: 20488644
61. Queen, S.A.; Sanchez, C.F.; Lopez, S.R.; et al. Doseand agedependent effects of prenatal ethanol exposure on hippocampal metabotropicglutamate receptorstimulated phosphoinositide hydrolysis. Alcoholism: Clinical and Experimental Research 17:887-893, 1993. PMID: 8214431
62. Ramocki, M.B., and Zoghbi, H.Y. Failure of neuronal homeostasis results in common neuropsychiatric phenotypes. Nature 455:912-918, 2008. PMID: 18923513
63. Richardson, D.P.; Byrnes, M.L.; Brien, J.F.; et al. Impaired acquisition in the water maze and hippocampal longterm potentiation after chronic prenatal ethanol exposure in the guineapig. European Journal of Neuroscience 16:1593-1598, 2002. PMID: 12405973
64. Samudio-Ruiz, S.L.; Allan, A.M.; Sheema, S.; and Caldwell, K.K. Hippocampal NmethylDaspartate receptor subunit expression profiles in a mouse model of prenatal alcohol exposure. Alcoholism: Clinical and Experimental Research 34:342-353, 2010. PMID: 19951292
65. Samudio-Ruiz, S.L.; Allan, A.M.; Valenzuela, C.F.; et al. Prenatal ethanol exposure persistently impairs NMDA receptordependent activation of extracellular signalregulated kinase in the mouse dentate gyrus. Journal of Neurochemistry 109:1311-1323, 2009. PMID: 19317851
66. Sanderson, J.L.; Partridge, L.D.; and Valenzuela, C.F. Modulation of GABAergic and glutamatergic transmission by ethanol in the developing neocortex: An in vitro test of the excessive inhibition hypothesis of fetal alcohol spectrum disorder. Neuropharmacology 56:541-555, 2009. PMID: 19027758
67. Sathyan, P.; Golden, H.B.; and Miranda, R.C. Competing interactions between microRNAs determine neural progenitor survival and proliferation after ethanol exposure: Evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. Journal of Neuroscience 27:8546-8557, 2007. PMID: 17687032
68. Schneider, M.L.; Moore, C.F.; Barnhart, T.E.; et al. Moderatelevel prenatal alcohol exposure alters striatal dopamine system function in rhesus monkeys. Alcoholism: Clinical and Experimental Research 29:1685-1697, 2005. PMID: 16205369
69. Servais, L.; Hourez, R.; Bearzatto, B.; et al. Purkinje cell dysfunction and alteration of longterm synaptic plasticity in fetal alcohol syndrome. Proceedings of the National Academy of Sciences of the United States of America 104:9858-9863, 2007. PMID: 17535929
70. Shen, R.Y., and Choong, K.C. Different adaptations in ventral tegmental area dopamine neurons in control and ethanol exposed rats after methylphenidate treatment. Biological Psychiatry 59:635-642, 2006. PMID: 16199009
71. Thomas, J.D.; Garcia, G.G.; Dominguez, H.D.; and Riley, E.P. Administration of eliprodil during ethanol withdrawal in the neonatal rat attenuates ethanolinduced learning deficits. Psychopharmacology (Berl) 175:189-195, 2004. PMID: 15064913
72. Thompson, B.L.; Levitt, P.; and Stanwood, G.D. Prenatal exposure to drugs: Effects on brain development and implications for policy and education. Nature Reviews Neuroscience 10:303-312, 2009. PMID: 19277053
73. Toso, L.; Roberson, R.; Woodard, J.; et al. Prenatal alcohol exposure alters GABA(A)alpha5 expression: A mechanism of alcoholinduced learning dysfunction. American Journal of Obstetrics and Gynecology 195:522-527, 2006. PMID: 16643827
74. Vaglenova, J.; Pandiella, N.; Wijayawardhane, N.; et al. Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors. Neuropsychopharmacology 33:1071-1083, 2008. PMID: 17609677
75. Valenzuela, C.F.; Partridge, L.D.; Mameli, M.; and Meyer, D.A. Modulation of glutamatergic transmission by sulfated steroids: Role in fetal alcohol spectrum disorder. Brain Research Reviews 57:506-519, 2008. PMID: 17597219
76. Valles, S.; Felipo, V.; Montoliu, C.; and Guerri, C. Alcohol exposure during brain development reduces 3HMK801 binding and enhances metabotropicglutamate receptorstimulated phosphoinositide hydrolysis in rat hippocampus. Life Sciences 56:1373-1383, 1995. PMID: 8847948
77. Wang, J.; Haj-Dahmane, S.; and Shen, R.Y. Effects of prenatal ethanol exposure on the excitability of ventral tegmental area dopamine neurons in vitro. Journal of Pharmacology and Experimental Therapeutics 319:857-863, 2006. PMID: 16905687
78. Webster, W.S.; Walsh, D.A.; McEwen, S.E.; and Lipson, A.H. Some teratogenic properties of ethanol and acetaldehyde in C57BL/6J mice: Implications for the study of the fetal alcohol syndrome. Teratology 27:231-243, 1983. PMID: 6867945
79. Weinberg, J.; Sliwowska, J.H.; Lan, N.; and Hellemans, K.G. Prenatal alcohol exposure: Foetal programming, the hypothalamicpituitaryadrenal axis and sex differences in outcome. Journal of Neuroendocrinology 20:470-488, 2008. PMID: 18266938
80. Wijayawardhane, N.; Shonesy, B.C.; Vaglenova, J.; et al. Postnatal aniracetam treatment improves prenatal ethanol induced attenuation of AMPA receptormediated synaptic transmission. Neurobiology of Disease 26:696-706, 2007. PMID: 17493826
81. Wijayawardhane, N.; Shonesy, B.C.; Vaithianathan, T.; et al. Ameliorating effects of preadolescent aniracetam treatment on prenatal ethanolinduced impairment in AMPA receptor activity. Neurobiology of Disease 29:81-91, 2008. PMID: 17916430
82. Yates, W.R.; Cadoret, R.J.; Troughton, E.P.; et al. Effect of fetal alcohol exposure on adult symptoms of nicotine, alcohol, and drug dependence. Alcoholism: Clinical and Experimental Research 22:914-920, 1998. PMID: 9660322
83. Youngentob, S.L., and Glendinning, J.I. Fetal ethanol exposure increases ethanol intake by making it smell and taste better. Proceedings of the National Academy of Sciences of the United States of America 106:5359-5364, 2009. PMID: 19273846
84. Zhou, F.C.; Fang, Y.; and Goodlett, C. Peptidergic agonists of activitydependent neurotrophic factor protect against prenatal alcoholinduced neural tube defects and serotonin neuron loss. Alcoholism: Clinical and Experimental Research 32:1361-1371, 2008. PMID: 18565153
85. Zhou, F.C.; Sari, Y.; and Powrozek, T.A. Fetal alcohol exposure reduces serotonin innervation and compromises development of the forebrain along the serotonergic pathway. Alcoholism: Clinical and Experimental Research 29:141-149, 2005. PMID: 15654302
86. Zucca, S., and Valenzuela, C.F. Low concentrations of alcohol inhibit BDNFdependent GABAergic plasticity via Ltype Ca2+ channel inhibition in developing CA3 hippocampal pyramidal neurons. Journal of Neuroscience 30:6776-6781, 2010. PMID: 2046323