Modulation of GABAergic and glutamatergic transmission by ethanol in the developing neocortex: An in vitro test of the excessive inhibition hypothesis of fetal alcohol spectrum disorder

Neuropharmacology

Volumn 56, Issue 2, 2009, Pages 541-555

  Sanderson, Jennifer L ^a   Donald Partridge, L ^a   Fernando Valenzuela, C ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

Alcohol; Development; Excitability; Neocortex; Neurotransmitter; Release

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; CALCIUM; CARRIER PROTEIN; GLUTAMIC ACID; MESSENGER RNA; MUSCIMOL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POSTSYNAPTIC RECEPTOR; PROTEIN KCC2; PROTEIN NKCC1; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID RELEASE; ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN SLICE; CONTROLLED STUDY; DEPOLARIZATION; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; FETAL ALCOHOL SYNDROME; FETUS; GABAERGIC TRANSMISSION; GENE EXPRESSION; IN VITRO STUDY; NEOCORTEX; NERVE CELL EXCITABILITY; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROMODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARIETAL LOBE; PATCH CLAMP; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; SYNAPTOGENESIS;

ANIMALS; ANIMALS, NEWBORN; BIOPHYSICS; CALCIUM; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DIZOCILPINE MALEATE; ELECTRIC STIMULATION; ETHANOL; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GABA AGONISTS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUTAMIC ACID; MALE; MEMBRANE POTENTIALS; MUSCIMOL; NEOCORTEX; PATCH-CLAMP TECHNIQUES; PREGNANCY; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM-POTASSIUM-CHLORIDE SYMPORTERS; SYMPORTERS; SYNAPTIC TRANSMISSION;

EID: 58549095048     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2008.10.012     Document Type: Article

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