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(a) For selected reviews of organocatalysis, see: (a) Special Issue: Asymmetric Organocatalysis. Acc. Chem. Res. 2004, 37, 487-631.;
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79960939394
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Ref. 13c.; The use of chiral cyclophanyl phosphine as a reagent for the kinetic resolution of hydroperoxides has been reported by
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(d) Ref. 13c.; The use of chiral cyclophanyl phosphine as a reagent for the kinetic resolution of hydroperoxides has been reported by:
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For syntheses of pseudo-ortho-substituted aryl[2.2]paracyclophanes with the axial chirality of the biaryl fragment, see
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For syntheses of pseudo-ortho-substituted aryl[2.2]paracyclophanes with the axial chirality of the biaryl fragment, see: (a) Rosenberg, V.; Zhuravsky, R.; Sergeeva, E. Chirality 2006, 18, 95-102;
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(a) Schneider, J. F.; Falk, F. C.; Fröhlich, R.; Paradies, J. Eur. J. Org. Chem. 2010, 2265-2269;
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79960949195
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note
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p)-4.
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61
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0345529047
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To the best of our knowledge, no systematic study of the palladium-catalyzed amination of haloaryl triflates has been reported. Buchwald et al. demonstrated that in the reaction of bromoaryl nonaflates, the selective substitution of the nonaflate moiety could be achieved in good yields with use of BINAP ligand. However, they also reported that in the reaction of 4- bromophenyl nonaflate with aniline, the amine was selectively substituted for the bromide in preference to the nonaflate with use of (2-biphenyl)di- tertbutylphosphine as the ligand.
-
To the best of our knowledge, no systematic study of the palladium-catalyzed amination of haloaryl triflates has been reported. Buchwald et al. demonstrated that in the reaction of bromoaryl nonaflates, the selective substitution of the nonaflate moiety could be achieved in good yields with use of BINAP ligand. However, they also reported that in the reaction of 4- bromophenyl nonaflate with aniline, the amine was selectively substituted for the bromide in preference to the nonaflate with use of (2-biphenyl)di- tertbutylphosphine as the ligand. Anderson, K. W.; Mendez-Perez, M.; Priego, J.; Buchwald, S. L. J. Org. Chem. 2003, 68, 9563-9573.
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33751385493
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In the case of Suzuki-Miyaura coupling reaction, aryl triflates are known to be less reactive than the corresponding bromides
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In the case of Suzuki-Miyaura coupling reaction, aryl triflates are known to be less reactive than the corresponding bromides. (a) Oh-e, T.; Miyaura, N.; Suzuki, A. J. Org. Chem. 1993, 58, 2201-2208.
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79960937083
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note
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3a this could be an alternative synthetic method for PHANEPHOS.
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65
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0042250071
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(a) Matsumura, K.; Shimizu, H.; Saito, T.; Kumobayashi, H. Adv. Synth. Catal. 2003, 345, 180-184;
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(2003)
Adv. Synth. Catal.
, vol.345
, pp. 180-184
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Matsumura, K.1
Shimizu, H.2
Saito, T.3
Kumobayashi, H.4
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