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3. [2.2]PHANEPHOS = 4,12-bis(diphenylphosphino)-[2.2]paracyclophane.
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10. For recent structural information see Wiles, J.A.; Bergens, S.H.; Young, V.G. J. Am. Chem. Soc. 1997, 779, 2940 and references cited therein.
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24
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0010344795
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note
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2) led to a much less active species.
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25
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0025963677
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13. Heiser, B.; Broger, E.A.; Crameri, Y. Tetrahedron: Asymmetry 1991, 2, 51.
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26
-
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0010341070
-
-
note
-
3OH) δ 7.91 (br t, J-8, 4 H), 7.55 (overlapping m, 4 H), 7.35 (t, J=7.6, 4 H), 7.26 (br t, J-7, 4 H), 7.25 (m, 2 H), 7.13 (t, J=7.6, 4 H), 6.53(br d, J=8.0, 2 H), 6.44 (m, 2 H), 2.66 (m, 4 H), 2.36 (ddd, J=13.7, 10.4, 3.4, 2 H), 1.80 (ddd, J=13.7, 10.4, 5.6, 2 H).
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27
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0003400107
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John Wiley & Sons, Inc., New York
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15. Use of the trifluoroacetate counter ion has previously been reported to give lower selectivities in the hydrogenation than the corresponding dihalide species, see Noyori, R. Asymmetric Catalysis in Organic Synthesis; John Wiley & Sons, Inc., New York, 1994.
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Noyori, R.1
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0010390670
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note
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16. Variations of up to 5% ee were observed.
-
-
-
-
29
-
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0010344973
-
-
note
-
1H NMR. Enantioselectivity was determined by gc analysis.
-
-
-
-
30
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84981828672
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18. For a definition of the chiral descriptor see: (a) Cahn, R.S.; Ingold, L; Prelog, V. Angew. Chem. Int. Ed. Engl. 1966, 5, 385.
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