Improved synthesis of (±)-4,12-dihydroxy[2.2]paracyclophane and Its enantiomeric resolution by enzymatic methods: Planar chiral (R)- and (S)-phanol

Journal of Organic Chemistry

Volumn 67, Issue 24, 2002, Pages 8679-8681

  Braddock, D Christopher ^a   MacGilp, Iain D ^b   Perry, Benjamin G ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLIZATION; ENZYME KINETICS; HYDROLYSIS;

ENANTIOMERS;

SYNTHESIS (CHEMICAL);

4,12 DIHYDROXY[2.2]PARACYCLOPHANE; PARACYCLOPHANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLIZATION; ENANTIOMER; ENZYME ANALYSIS; ENZYME ISOLATION; ENZYME KINETICS; HYDROLYSIS; SYNTHESIS;

EID: 2242448021     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo020451x     Document Type: Article

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