Integrin-linked kinase regulates phosphatase and tensin homologue activity to promote tumorigenesis in neuroblastoma cells

Surgery

Volumn 150, Issue 2, 2011, Pages 162-168

  Taylor, Chase J ^a   Qiao, Jingbo ^a   Colon, Nadja C ^a   Schlegel, Cameron ^a   Josifi, Erlena ^a   Chung, Dai H ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN LINKED KINASE; PHOSPHATASE AND TENSIN HOMOLOGUE; PHOSPHATIDYLINOSITOL 3 KINASE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; ENZYME REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; NEUROBLASTOMA; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION;

EID: 79960929335     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2011.05.007     Document Type: Article

References (21)

1. B.H. Kushner, K. Kramer, M.P. LaQuaglia, S. Modak, K. Yataghene, and N.K. Cheung Reduction from seven to five cycles of intensive induction chemotherapy in children with high-risk neuroblastoma J Clin Oncol 22 2004 4888 4892 (Pubitemid 46638612)
2. T.A. Ishola, J. Kang, J. Qiao, B.M. Evers, and D.H. Chung Phosphatidylinositol 3-kinase regulation of gastrin-releasing peptide-induced cell cycle progression in neuroblastoma cells Biochim Biophys Acta 1770 2007 927 932 (Pubitemid 46617033)
3. A. Bender, D. Opel, I. Naumann, R. Kappler, L. Friedman, and D. von Schweinitz PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis Oncogene 30 2011 474 503
4. P.C. McDonald, and S. Dedhar The role of integrin-linked kinase in cancer development and progression R. Zent, A. Pozzi, R. Zent, As Pozzi, Cell-extracellular matrix interactions in cancer 2010 Springer New York 245 273
5. A. Meyer, C.M. van Golen, M. Boyanapalli, B. Kim, M.E. Soules, and E.L. Feldman Integrin-linked kinase complexes with caveolin-1 in human neuroblastoma cells Biochemistry 44 2005 932 938 (Pubitemid 40129653)
6. G. Hannigan, A.A. Troussard, and S. Dedhar Integrin-linked kinase: a cancer therapeutic target unique among its ILK Nat Rev Cancer 5 2005 51 63 (Pubitemid 40052325)
7. G.E. Hannigan, C. Leung-Hagesteijn, L. Fitz-Gibbon, M.G. Coppolino, G. Radeva, and J. Filmus Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase Nature 379 1996 91 96 (Pubitemid 26008142)
8. R.A. Weinberg The biology of cancer 2006 Garland Science London
9. S. Persad, S. Attwell, V. Gray, N. Mawji, J.T. Deng, and D. Leung Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343 J Biol Chem 276 2001 27462 27469
10. I. Eke, S. Hehlgans, and N. Cordes There's something about ILK Int J Radiat Biol 85 2009 929 936
11. T.D. Bunney, and M. Katan Phosphoinositide signalling in cancer: beyond PI3K and PTEN Nat Rev Cancer 10 2010 342 352
12. M. Delcommenne, C. Tan, V. Gray, L. Rue, J. Woodgett, and S. Dedhar Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase Proc Natl Acad Sci U S A 95 1998 11211 11216 (Pubitemid 28450107)
13. J. Downward Mechanisms and consequences of activation of protein kinase B/Akt Curr Opin Cell Biol 10 1998 262 267 (Pubitemid 28174769)
14. A. Toker, and L.C. Cantley Signalling through the lipid products of phosphoinositide-3-OH kinase Nature 387 1997 673 676 (Pubitemid 27270600)
15. S. Zhang, and D. Yu PI(3)king apart PTEN's role in cancer Clin Cancer Res 16 2010 4325 4330
16. Z. Wang, X. Wang, J. Li, X. Sun, and X. Wang The expression significance and associativity of ILK and PTEN in gastric cancer tissue The Chinese-German Journal of Clinical Oncology 7 2008 701 703
17. S. Attwell, J. Mills, A. Troussard, C. Wu, and S. Dedhar Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN Mol Biol Cell 14 2003 4813 4825 (Pubitemid 37484798)
18. J. Ponten Spontaneous and virus induced transformation in cell culture Virol Monogr 8 1971 1 253
19. M. Tamura, J. Gu, H. Tran, and K.M. Yamada PTEN gene and integrin signaling in cancer J Natl Cancer Inst 91 1999 1820 1828
20. G. Rosenberger, I. Jantke, A. Gal, and K. Kutsche Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling Hum Mol Genet 12 2003 155 167 (Pubitemid 36124451)
21. Z. Li, X. Dong, Z. Wang, W. Liu, N. Deng, and Y. Ding Regulation of PTEN by Rho small GTPases Nat Cell Biol 7 2005 399 404 (Pubitemid 40533130)