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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 16, 2011, Pages 4758-4761

Discovery of indazoles as inhibitors of Tpl2 kinase

(15) Hu, Yonghan a Cole, Derek b Denny, Rajiah Aldrin a Anderson, David R a Ipek, Manus a Ni, Yike a Wang, Xiaolun a Thaisrivongs, Suvit a Chamberlain, Timothy a Hall, J Perry a Liu, Julie a Luong, Michael a Lin, Lih Ling a Telliez, Jean Baptiste a Gopalsamy, Ariamala a

a PFIZER INC (United States)

b Takeda San Diego ^* (United States)

Author keywords

Indazole; Rheumatoid arthritis; Tpl2 kinase

Indexed keywords

INDAZOLE DERIVATIVE; PROTEIN SERINE THREONINE KINASE; TPL2 KINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ENZYME INHIBITORS; HUMANS; INDAZOLES; MAP KINASE KINASE KINASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MONOCYTES; PROTO-ONCOGENE PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960914783 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.06.065 Document Type: Article

Times cited : (20)

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