Targeting CXCR3 reduces ligand-induced T-Cell activation but not development of lung allergic responses

Annals of Allergy, Asthma and Immunology

Volumn 107, Issue 2, 2011, Pages 145-153

  Shin, Yoo Seob ^a   Takeda, Katsuyuki ^a   Ohnishi, Hiroshi ^a   Jia, Yi ^a   Shiraishi, Yoshiki ^a   Cox, Maryann L ^b   Fine, Jay S ^c   Rosenblum, Stuart ^b   Lundel, Daniel ^b   Jenh, Chung Her ^b   Manfra, Denise J ^b   Gelfand, Erwin W ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR3 ANTAGONIST; CYTOKINE; INTERLEUKIN 2; LIGAND; OVALBUMIN; SCH 104; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ASTHMA; BRONCHUS HYPERREACTIVITY; CALCIUM TRANSPORT; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; DRUG TARGETING; EFFECTOR CELL; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LUNG LAVAGE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY FUNCTION; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; REVIEW; T LYMPHOCYTE ACTIVATION; TH2 CELL;

EID: 79960908090     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/j.anai.2011.04.013     Document Type: Article

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