Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway

Journal of Biomedical Science

Volumn 18, Issue 1, 2011, Pages

  Tian, Yikui ^a   Zhang, Wenjuan ^a   Xia, Dachuan ^a   Modi, Paul ^b   Liang, Degang ^a   Wei, Minxin ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b LIVERPOOL HEART AND CHEST HOSPITAL   (United Kingdom)

Author keywords

apoptosis; Bcl 2; Ischemia reperfusion injury; JAK2 STAT3 pathway; postconditioning

Indexed keywords

JANUS KINASE 2; MESSENGER RNA; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN BCL 2; PROTEIN KINASE B; STAT3 PROTEIN; TRIPHENYLTETRAZOLIUM; WORTMANNIN; ALPHA CYANO (3,4 DIHYDROXY) N BENZYLCINNAMIDE; ALPHA-CYANO-(3,4-DIHYDROXY)-N-BENZYLCINNAMIDE; ANDROSTANE DERIVATIVE; JAK2 PROTEIN, RAT; PHOSPHATIDYLINOSITOL 3 KINASE; STAT3 PROTEIN, RAT; TYRPHOSTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IMMUNOHISTOCHEMISTRY; ISCHEMIC POSTCONDITIONING; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; PROTEIN FUNCTION; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; HEART MUSCLE; HEART MUSCLE REPERFUSION; METABOLISM; METHODOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS;

ANDROSTADIENES; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; ISCHEMIC POSTCONDITIONING; JANUS KINASE 2; MYOCARDIAL REPERFUSION; MYOCARDIUM; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; STAT3 TRANSCRIPTION FACTOR; TYRPHOSTINS;

EID: 79960889799     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-18-53     Document Type: Article

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