Dynamic progression of contractile and endothelial dysfunction and infarct extension in the late phase of reperfusion

Journal of Surgical Research

Volumn 94, Issue 2, 2000, Pages 133-144

  Zhao, Zhi Qing ^a   Nakamura, Masanori ^a   Wang, Ning Ping ^a   Velez, Daniel A ^a   Hewan Lowe, Karlene O ^a   Guyton, Robert A ^a   Vinten Johansen, Jakob ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Contractile function; Endothelium; Infarct size; Myocardial blood flow; Neutrophil; Reperfusion

Indexed keywords

CREATINE KINASE; MYELOPEROXIDASE; TRIPHENYLTETRAZOLIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY CIRCUMFLEX BRANCH; ENDOTHELIUM; ENZYME ACTIVITY; FEMALE; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; IMMUNOHISTOCHEMISTRY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; WESTERN BLOTTING;

EID: 0033664599     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.2000.6029     Document Type: Article

References (58)

1. The microcirculation and inflammation: Modulation of leukocyte-endothelial cell adhesion
2. Modulation of leukocyte-mediated myocardial reperfusion injury
3. Reperfusion induced injury: Manifestations, mechanisms, and clinical relevance [Review]
4. Canine myocardial reperfusion injury: Its reduction by the combined administration of superoxide dismutase and catalase
5. Cellular pathology. I: Cell injury and cell death
6. Neutrophils as potential participants in acute myocardial ischemia: Relevance to reperfusion
7. Regulation of intercellular adhesion molecule-1 (ICAM-1) in ischemic and reperfused canine myocardium
8. Adherence of neutrophils to canine cardiac myocytes in vitro is dependent on intercellular adhesion molecule-1
9. Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence
10. The role of neutrophils and free radicals in ischemic myocardial injury
11. CDw18 dependent adhesion of leukocytes to endothelium and its relevance for cardiac reperfusion
12. Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage
13. Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog
14. Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia: Evidence for neutrophil-mediated reperfusion injury
15. Endothelial cell injury in cardiovascular surgery: The systemic inflammatory response
16. Induction of interleukin-8 expression during cardiopulmonary bypass
17. Identification of a time window for therapy to reduce experimental canine myocardial injury: Suppression of neutrophil activation during 72 hours of reperfusion
18. Prevention of coronary vascular abnormalities early in reperfusion with TGF-β may not prevent late coronary vascular injury
19. The leukocyte cell adhesion cascade and its role in myocardial ischemia-reperfusion injury
20. A fresh look at reperfusion injury
21. Administration of adenosine during reperfusion reduces injury of vascular endothelium and death of myocytes
22. 2-receptor activation inhibits neutrophil-mediated injury to coronary endothelium
23. Adenosine inhibition of neutrophil damage during reperfusion does not involve K(ATP)-channel activation
24. Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries
25. Myocardial stunning and preconditioning: Age, species, and model related differences: Role of AMP-5'-nucleotidase in myocardial injury and protection [Review]
26. Clinical evidence of myocardial stunning in patients undergoing CABG surgery
27. Myocardial stunning: An overview
28. Time course and determinants of recovery of function after reversible ischemia in conscious dogs
29. Clinical perspective. Reperfusion injury: Laboratory phenomenon or clinical reality?
30. In-hospital causes of death in the patients admitted to the GISSI study
31. Role of neutrophils in myocardial stunning after brief ischaemia: The end of a six year old controversy (1987-1993) [Comment]
32. The relationship between regional blood flow and contractile function in normal, ischemic, and reperfused myocardium
33. Selective enhancement of function of stunned myocardium by increased flow
34. Prolonged impairment of coronary vasodilation after reversible ischemia
35. Preservation of coronary flow reserve in stunned myocardium
36. Potential role of neutrophil antiadhesion therapy in myocardial stunning, myocardial infarction, and organ dysfunction after cardiopulmonary bypass
37. Complete prevention of myocardial stunning, contracture, low-reflow, and edema after heart transplantation by blocking neutrophil adhesion molecules during reperfusion
38. Myocardial consequences of reperfusion
39. Role of leukocytes in response to acute myocardial ischemia and reflow in dogs
40. Time course of coronary endothelial healing after injury due to ischemia and reperfusion
41. Combined adenosine and lidocaine administration limits myocardial reperfusion injury
42. Inflammation in the course of early myocardial ischemia
43. Early membrane damage during coronary reperfusion in dogs: Detection by radiolabelled anticardiac myosin (Fab')2
44. Progression of myocardial necrosis during reperfusion of ischemic myocardium
45. Molecular mechanisms of leukocyte recruitment in the inflammatory process
46. Role of early reperfusion in the induction of adhesion molecules and cytokines in previously ischemic myocardium
47. Mechanisms and consequences of cell cactivation in the microcirculation
48. Microvascular compression during myocardial ischemia: Mechanistic basis for no-reflow phenomenon
49. Acute and Chronic Inflammation
50. Magnitude and time course of microvascular obstruction and tissue injury after acute myocardial infarction
51. Role of leukocytes in acute myocardial infarction in anesthetized dogs: Relationship to myocardial salvage by anti-inflammatory drugs
52. Neutrophil accumulation in ischemic canine myocardium: Insights into time course, distribution, and mechanism of localization during early reperfusion
53. Quantification of neutrophil migration following myocardial ischemia and reperfusion in cats and dogs
54. Exposure of human neutrophils to exogenous nucleotides causes elevation in intracellular calcium, transmembrane calcium fluxes, and an alteration of a cytosolic factor resulting in enhanced superoxide production in response to FMLP and arachidonic acid
55. Resident cardiac mast cells degranulate and release preformed TNF-α, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion
56. Macrophages express osteopontin during rapair of myocardial necrosis
57. Mast cells contribute to ischemia-reperfusion-induced granulocyte infiltration and intestinal dysfunction
58. Tumor necrosis factor-α in macrophages of heart, liver, kidney, and in the pituitary gland