PDGF induced microRNA alterations in cancer cells

Nucleic Acids Research

Volumn 39, Issue 10, 2011, Pages 4035-4047

  Shao, Minghai ^a,b   Rossi, Simona ^c   Chelladurai, Bhadrani ^a,b   Shimizu, Masayoshi ^c   Ntukogu, Obiageli ^a,b   Ivan, Mircea ^a,b,d   Calin, George A ^c   Matei, Daniela ^a,b,e,f  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d Department of Obstetrics and Gynecology ^*  (United States)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f VA Roudebush Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; LET 7D PROTEIN; MICRORNA; MICRORNA 146B; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN C FOS; RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA; EPIDERMAL GROWTH FACTOR; MIRN146 MICRORNA, HUMAN; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET-DERIVED GROWTH FACTOR A; PLATELET-DERIVED GROWTH FACTOR BB;

ARTICLE; CANCER CELL; CONTROLLED STUDY; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INDUCTION; GENE MUTATION; GENE REPRESSION; GENETIC TRANSFECTION; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; LIGAND BINDING; MICROARRAY ANALYSIS; OVARY CANCER; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; BIOSYNTHESIS; CELL LINE; FEMALE; GENETICS; METABOLISM; OVARY TUMOR;

CELL LINE; EPIDERMAL GROWTH FACTOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; MICRORNAS; OVARIAN NEOPLASMS; PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 79960833464     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq1305     Document Type: Article

References (52)

1. Matsui, T., Heidaran, M., Miki, T., Popescu, N., La Rochelle, W., Kraus, M., Pierce, J. and Aaronson, S. (1989) Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science, 243, 800-804. (Pubitemid 19062635)
2. Hart, C.E., Forstrom, J.W., Kelly, J.D., Seifert, R.A., Smith, R.A., Ross, R., Murray, M.J. and Bowen-Pope, D.F. (1988) Two classes of PDGF receptor recognize different isoforms of PDGF. Science, 240, 1529-1531.
3. Yao, R. and Cooper, G.M. (1995) Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science, 267, 2003-2006.
4. Huang, J.S., Huang, S.S. and Deuel, T.F. (1984) Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors. Cell, 39, 79-87. (Pubitemid 15218227)
5. Greenhalgh, D.G., Sprugel, K.H., Murray, M.J. and Ross, R. (1990) PDGF and FGF stimulate wound healing in the genetically diabetic mouse. Am. J. Pathol., 136, 1235-1246. (Pubitemid 20210322)
6. Antoniades, H.N. and Hunkapiller, M.W. (1983) Human platelet-derived growth factor (PDGF): amino-terminal amino acid sequence. Science, 220, 963-965. (Pubitemid 13081934)
7. Yu, J.C., Mahadevan, D., LaRochelle, W.J., Pierce, J.H. and Heidaran, M.A. (1994) Structural coincidence of alpha PDGFR epitopes binding to platelet-derived growth factor-AA and a potent neutralizing monoclonal antibody. J. Biol. Chem., 269, 10668-10674.
8. Li, X., Ponten, A., Aase, K., Karlsson, L., Abramsson, A., Uutela, M., Backstrom, G., Hellstrom, M., Bostrom, H., Li, H. et al. (2000) PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor. Nat. Cell Biol., 2, 302-309.
9. LaRochelle, W.J., Jeffers, M., McDonald, W.F., Chillakuru, R.A., Giese, N.A., Lokker, N.A., Sullivan, C., Boldog, F.L., Yang, M., Vernet, C. et al. (2001) PDGF-D, a new protease-activated growth factor. Nat. Cell Biol., 3, 517-521. (Pubitemid 32422090)
10. Kazlauskas, A. and Cooper, J.A. (1989) Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins. Cell, 58, 1121-1133. (Pubitemid 19238189)
11. Westermark, B., Siegbahn, A., Heldin, C.H. and Claesson-Welsh, L. (1990) B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase. Proc. Natl Acad. Sci. USA, 87, 128-132.
12. Heidaran, M.A., Beeler, J.F., Yu, J.C., Ishibashi, T., LaRochelle, W.J., Pierce, J.H. and Aaronson, S.A. (1993) Differences in substrate specificities of alpha and beta platelet-derived growth factor (PDGF) receptors. Correlation with their ability to mediate PDGF transforming functions. J. Biol. Chem., 268, 9287-9295. (Pubitemid 23145973)
13. Fatatis, A. and Miller, R.J. (1997) Platelet-derived growth factor (PDGF)-induced Ca2+signaling in the CG4 oligodendroglial cell line and in transformed oligodendrocytes expressing the beta-PDGF receptor. J. Biol. Chem., 272, 4351-4358. (Pubitemid 27078510)
14. Mao, X. and Hamoudi, R.A. (2000) Molecular and cytogenetic analysis of glioblastoma multiforme. Cancer Genet. Cytogenet., 122, 87-92.
15. Oda, Y., Wehrmann, B., Radig, K., Walter, H., Rose, I., Neumann, W. and Roessner, A. (1995) Expression of growth factors and their receptors in human osteosarcomas. Immunohistochemical detection of epidermal growth factor, platelet-derived growth factor and their receptors: its correlation with proliferating activities and p53 expression. Gen. Diagn. Pathol., 141, 97-103.
16. Henriksen, R., Funa, K., Wilander, E., Backstrom, T., Ridderheim, M. and Oberg, K. (1993) Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms. Cancer Res., 53, 4550-4554. (Pubitemid 23304378)
17. Matei, D., Chang, D.D. and Jeng, M.H. (2004) Imatinib mesylate (Gleevec) inhibits ovarian cancer cell growth through a mechanism dependent on platelet-derived growth factor receptor alpha and Akt inactivation. Clin. Cancer Res., 10, 681-690. (Pubitemid 38174008)
18. Carroll, M., Tomasson, M.H., Barker, G.F., Golub, T.R. and Gilliland, D.G. (1996) The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways. Proc. Natl Acad. Sci. USA, 93, 14845-14850.
19. Heinrich, M.C., Corless, C.L., Duensing, A., McGreevey, L., Chen, C.J., Joseph, N., Singer, S., Griffith, D.J., Haley, A., Town, A. et al. (2003) PDGFRA activating mutations in gastrointestinal stromal tumors. Science, 299, 708-710. (Pubitemid 36159485)
20. Betsholtz, C., Westermark, B., Ek, B. and Heldin, C.H. (1984) Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: implications for autocrine receptor activation. Cell, 39, 447-457. (Pubitemid 15198584)
21. Dai, C., Celestino, J.C., Okada, Y., Louis, D.N., Fuller, G.N. and Holland, E.C. (2001) PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev., 15, 1913-1925. (Pubitemid 32738621)
22. Ma, D., Nutt, C.L., Shanehsaz, P., Peng, X., Louis, D.N. and Kaetzel, D.M. (2005) Autocrine platelet-derived growth factor-dependent gene expression in glioblastoma cells is mediated largely by activation of the transcription factor sterol regulatory element binding protein and is associated with altered genotype and patient survival in human brain tumors. Cancer Res., 65, 5523-5534. (Pubitemid 40911152)
23. Westermark, B., Heldin, C.H. and Nister, M. (1995) Platelet-derived growth factor in human glioma. Glia, 15, 257-263.
24. Matei, D., Emerson, R.E., Lai, Y.C., Baldridge, L.A., Rao, J., Yiannoutsos, C. and Donner, D.D. (2006) Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer. Oncogene, 25, 2060-2069.
25. Lokker, N.A., Sullivan, C.M., Hollenbach, S.J., Israel, M.A. and Giese, N.A. (2002) Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors. Cancer Res., 62, 3729-3735. (Pubitemid 34728854)
26. Jackson, E.L., Garcia-Verdugo, J.M., Gil-Perotin, S., Roy, M., Quinones-Hinojosa, A., VandenBerg, S. and Alvarez-Buylla, A. (2006) PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron, 51, 187-199. (Pubitemid 44063617)
27. Dolloff, N.G., Russell, M.R., Loizos, N. and Fatatis, A. (2007) Human bone marrow activates the Akt pathway in metastatic prostate cells through transactivation of the alpha-platelet-derived growth factor receptor. Cancer Res., 67, 555-562. (Pubitemid 46192192)
28. Hermanson, M., Funa, K., Hartman, M., Claesson-Welsh, L., Heldin, C.H., Westermark, B. and Nister, M. (1992) Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res., 52, 3213-3219.
29. Rodriguez-Viciana, P., Warne, P.H., Dhand, R., Vanhaesebroeck, B., Gout, I., Fry, M.J., Waterfield, M.D. and Downward, J. (1994) Phosphatidylinositol-3- OH kinase as a direct target of Ras. Nature, 370, 527-532. (Pubitemid 24264918)
30. Calin, G.A. and Croce, C.M. (2006) MicroRNA signatures in human cancers. Nat. Rev. Cancer, 6, 857-866. (Pubitemid 44629897)
31. Foekens, J.A., Sieuwerts, A.M., Smid, M., Look, M.P., de Weerd, V., Boersma, A.W., Klijn, J.G., Wiemer, E.A. and Martens, J.W. (2008) Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer. Proc. Natl Acad. Sci. USA, 105, 13021-13026.
32. Farh, K.K., Grimson, A., Jan, C., Lewis, B.P., Johnston, W.K., Lim, L.P., Burge, C.B. and Bartel, D.P. (2005) The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science, 310, 1817-1821. (Pubitemid 41814382)
33. Johnson, C.D., Esquela-Kerscher, A., Stefani, G., Byrom, M., Kelnar, K., Ovcharenko, D., Wilson, M., Wang, X., Shelton, J., Shingara, J. et al. (2007) The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res., 67, 7713-7722. (Pubitemid 47281364)
34. Calin, G.A., Dumitru, C.D., Shimizu, M., Bichi, R., Zupo, S., Noch, E., Aldler, H., Rattan, S., Keating, M., Rai, K. et al. (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl Acad. Sci. USA, 99, 15524-15529. (Pubitemid 35403967)
35. Kulshreshtha, R., Ferracin, M., Wojcik, S.E., Garzon, R., Alder, H., Agosto-Perez, F.J., Davuluri, R., Liu, C.G., Croce, C.M., Negrini, M. et al. (2007) A microRNA signature of hypoxia. Mol. Cell Biol., 27, 1859-1867.
36. Maillot, G., Lacroix-Triki, M., Pierredon, S., Gratadou, L., Schmidt, S., Benes, V., Roche, H., Dalenc, F., Auboeuf, D., Millevoi, S. et al. (2009) Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growth. Cancer Res., 69, 8332-8340.
37. Castellano, L., Giamas, G., Jacob, J., Coombes, R.C., Lucchesi, W., Thiruchelvam, P., Barton, G., Jiao, L.R., Wait, R., Waxman, J. et al. (2009) The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response. Proc. Natl Acad. Sci. USA, 106, 15732-15737.
38. Gillan, L., Matei, D., Fishman, D.A., Gerbin, C.S., Karlan, B.Y. and Chang, D.D. (2002) Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility. Cancer Res., 62, 5358-5364. (Pubitemid 35024613)
39. Beppu, K., Jaboine, J., Merchant, M.S., Mackall, C.L. and Thiele, C.J. (2004) Effect of imatinib mesylate on neuroblastoma tumorigenesis and vascular endothelial growth factor expression. J. Natl Cancer Inst., 96, 46-55. (Pubitemid 38180959)
40. Pahlman, S., Johansson, I., Westermark, B. and Nister, M. (1992) Platelet-derived growth factor potentiates phorbol ester-induced neuronal differentiation of human neuroblastoma cells. Cell Growth Differ., 3, 783-790.
41. Reneker, L.W. and Overbeek, P.A. (1996) Lens-specific expression of PDGF-A alters lens growth and development. Dev. Biol., 180, 554-565. (Pubitemid 27037363)
42. Heldin, C.H., Ostman, A. and Ronnstrand, L. (1998) Signal transduction via platelet-derived growth factor receptors. Biochim. Biophys. Acta, 1378, F79-F113. (Pubitemid 28381127)
43. Barone, M.V. and Courtneidge, S.A. (1995) Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src. Nature, 378, 509-512.
44. Shimizu, T., Kinugawa, K., Yao, A., Sugishita, Y., Sugishita, K., Harada, K., Matsui, H., Kohmoto, O., Serizawa, T. and Takahashi, T. (1999) Platelet-derived growth factor induces cellular growth in cultured chick ventricular myocytes. Cardiovasc Res., 41, 641-653. (Pubitemid 29130628)
45. Hurst, D.R., Edmonds, M.D., Scott, G.K., Benz, C.C., Vaidya, K.S. and Welch, D.R. (2009) Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res., 69, 1279-1283.
46. Ma, L., Teruya-Feldstein, J. and Weinberg, R.A. (2007) Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature, 449, 682-688. (Pubitemid 47552092)
47. Kulshreshtha, R., Davuluri, R.V., Calin, G.A. and Ivan, M. (2008) A microRNA component of the hypoxic response. Cell Death Differ., 15, 667-671. (Pubitemid 351405070)
48. Yu, J., Deuel, T.F. and Kim, H.R. (2000) Platelet-derived growth factor (PDGF) receptor-alpha activates c-Jun NH2-terminal kinase-1 and antagonizes PDGF receptor-beta-induced phenotypic transformation. J. Biol. Chem., 275, 19076-19082. (Pubitemid 30422875)
49. Davis, B.N., Hilyard, A.C., Nguyen, P.H., Lagna, G. and Hata, A. (2009) Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype. J. Biol. Chem., 284, 3728-3738.
50. Chan, M.C., Hilyard, A.C., Wu, C., Davis, B.N., Hill, N.S., Lal, A., Lieberman, J., Lagna, G. and Hata, A. (2010) Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression. EMBO J., 29, 559-573.
51. Quintavalle, M., Elia, L., Condorelli, G. and Courtneidge, S.A. (2010) MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro. J. Cell Biol., 189, 13-22.
52. He, L., He, X., Lim, L.P., de Stanchina, E., Xuan, Z., Liang, Y., Xue, W., Zender, L., Magnus, J., Ridzon, D. et al. (2007) A microRNA component of the p53 tumour suppressor network. Nature, 447, 1130-1134. (Pubitemid 47014436)