메뉴 건너뛰기




Volumn 26, Issue 4, 2011, Pages 833-841

Stephania delavayi Diels. inhibits breast carcinoma proliferation through the p38 MAPK/NF-κB/COX-2 pathway

Author keywords

Apoptosis; Breast carcinomas; COX 2; Nuclear factor B; Stephania delavayi Diels.

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PACLITAXEL; PLANT EXTRACT; STEPHANIA DELAVAYI EXTRACT; UNCLASSIFIED DRUG;

EID: 79960820275     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1364     Document Type: Article
Times cited : (10)

References (42)
  • 1
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E and Mahadevan LC: Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 20: 117-122, 1995.
    • (1995) Trends Biochem Sci , vol.20 , pp. 117-122
    • Cano, E.1    Mahadevan, L.C.2
  • 2
    • 0032850020 scopus 로고    scopus 로고
    • p38 MAPK signalling cascades in inflammatory disease
    • DOI 10.1016/S1357-4310(99)01544-0, PII S1357431099015440
    • Herlaar E and Brown Z: p38MAPK signaling cascades in inflammatory disease. Mol Med Today 5: 439-447, 1999. (Pubitemid 29455026)
    • (1999) Molecular Medicine Today , vol.5 , Issue.10 , pp. 439-447
    • Herlaar, E.1    Brown, Z.2
  • 3
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-kappaB signaling: Balancing life and death - A new approach to cancer therapy
    • DOI 10.1172/JCI26322
    • Luo JL, Kamata H and Karin M: IKK/NF-kappaB signaling: balancing life and death, a new approach to cancer therapy. J Clin Invest 115: 2625-2632, 2005. (Pubitemid 41434385)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.10 , pp. 2625-2632
    • Luo, J.-L.1    Kamata, H.2    Karin, M.3
  • 4
    • 34748855636 scopus 로고    scopus 로고
    • NFκB and NFκBI polymorphisms in relation to susceptibility of tumour and other diseases
    • Sun XF and Zhang H: NFκB and NFκBI polymorphisms in relation to susceptibility of tumour and other diseases. Histol Histophatol 22: 1387-1398, 2007.
    • (2007) Histol Histophatol , vol.22 , pp. 1387-1398
    • Sun, X.1    Zhang, H.2
  • 5
    • 16644395843 scopus 로고    scopus 로고
    • Blocking anti-apoptosis as a strategy for cancer chemotherapy: NF-kappaB as a target
    • DOI 10.1002/jcb.20080
    • Monks NR, Biswas DK and Pardee AB: Blocking anti-apoptosis as a strategy for cancer chemotherapy: NF-kappaB as a target. J Cell Biochem 92: 646-650, 2004. (Pubitemid 44264255)
    • (2004) Journal of Cellular Biochemistry , vol.92 , Issue.4 , pp. 646-650
    • Monks, N.R.1    Biswas, D.K.2    Pardee, A.B.3
  • 6
    • 2942568164 scopus 로고    scopus 로고
    • Regulation of COX-2 protein expression by Akt in endometrial cancer cells is mediated through NF-kappaB/IkappaB pathway
    • St-Germain ME, Gagnon V, Parent S and Asselin E: Regulation of COX-2 protein expression by Akt in endometrial cancer cells is mediated through NF-kappaB/IkappaB pathway. Mol Cancer 3: 7, 2004.
    • (2004) Mol Cancer , vol.3 , pp. 7
    • St-Germain, M.E.1    Gagnon, V.2    Parent, S.3    Asselin, E.4
  • 7
    • 33646062906 scopus 로고    scopus 로고
    • Targeting the NF-kappaB pathway in estrogen receptor negative MDA-MB-231 breast cancer cells using small inhibitory RNAs
    • Monks NR and Pardee AB: Targeting the NF-kappaB pathway in estrogen receptor negative MDA-MB-231 breast cancer cells using small inhibitory RNAs. J Cell Biochem 98: 221-233, 2006.
    • (2006) J Cell Biochem , vol.98 , pp. 221-233
    • Monks, N.1    Pardee, A.B.2
  • 8
    • 0034671539 scopus 로고    scopus 로고
    • Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase
    • DOI 10.1074/jbc.M003224200
    • Jang BC, Sanchez T, Schaefers HJ, et al: Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase. J Biol Chem 275: 39507-39515, 2000. (Pubitemid 32058977)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.50 , pp. 39507-39515
    • Jang, B.-C.1    Sanchez, T.2    Schaefers, H.-J.3    Trifan, O.C.4    Liu, C.H.5    Creminon, C.6    Huang, C.-K.7    Hla, T.8
  • 9
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kappaB system: A treasure trove for drug development
    • Karin M, Yamamoto Y and Wang QM: The IKK NF-kappa B system: a treasure trove for drug development. Nat Rev Drug Discov 3: 17-26, 2004. (Pubitemid 38088695)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.1 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 10
    • 0036020941 scopus 로고    scopus 로고
    • NF-kappaB as a therapeutic target in cancer
    • Orlowski RZ and Baldwin AS Jr: NF-kappaB as a therapeutic target in cancer. Trends Mol Med 8: 385-389, 2002.
    • (2002) Trends Mol Med , vol.8 , pp. 385-389
    • Orlowski, R.1    Baldwin Jr., A.S.2
  • 13
    • 0037138743 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues
    • Thun MJ, Henley SJ and Patrono C: Non-steroidal anti-inflam-matory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues. J Natl Cancer Inst 94: 252-266, 2002. (Pubitemid 34196319)
    • (2002) Journal of the National Cancer Institute , vol.94 , Issue.4 , pp. 252-266
    • Thun, M.J.1    Jane, H.S.2    Patrono, C.3
  • 14
    • 79960797725 scopus 로고    scopus 로고
    • Biological safety and B cells activiation effects of Stephania delavayi Diels
    • Park DH, Li YC, Shim J, et al: Biological safety and B cells activiation effects of Stephania delavayi Diels. Mol Cell Toxicol 5: 93-98, 2009.
    • (2009) Mol Cell Toxicol , vol.5 , pp. 93-98
    • Park, D.H.1    Li, Y.C.2    Shim, J.3
  • 15
    • 54049087378 scopus 로고    scopus 로고
    • Induction of cell cycle arrest and apoptosis in myeloma cells by cepharanthine, a biscoclaurine alkaloid
    • Kikukawa Y, Okuno Y, Tatetsu H, et al: Induction of cell cycle arrest and apoptosis in myeloma cells by cepharanthine, a biscoclaurine alkaloid. Int J Oncol 33: 807-814, 2008.
    • (2008) Int J Oncol , vol.33 , pp. 807-814
    • Kikukawa, Y.1    Okuno, Y.2    Tatetsu, H.3
  • 16
    • 10844230330 scopus 로고    scopus 로고
    • Cip1
    • DOI 10.1158/0008-5472.CAN-04-0313
    • Meng LH, Zhang H, Hayward L, et al: Tetrandrine induces early G1 arrest in human colon carcinoma cells by down-regulating the activity and inducing the degradation of G1-S-specific cyclin-dependent kinases and by inducing p53 and p21Cip1. Cancer Res 64: 9086-9092, 2004. (Pubitemid 39665522)
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 9086-9092
    • Meng, L.-H.1    Zhang, H.2    Hayward, L.3    Takemura, H.4    Shao, R.-G.5    Pommier, Y.6
  • 17
    • 0027512858 scopus 로고
    • Bisbenzylisoquinoline alkaloids inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin
    • Yasukawa K, Akasu M, Takeuchi M, et al: Bisbenzylisoquinoline alkaloids inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Oncology 50: 137-140, 1993. (Pubitemid 23098734)
    • (1993) Oncology , vol.50 , Issue.2 , pp. 137-140
    • Yasukawa, K.1    Akasu, M.2    Takeuchi, M.3    Takido, M.4
  • 20
    • 1842836521 scopus 로고    scopus 로고
    • Evaluation of a gemcitabine-doxorubicin-paclitaxel combination schedule through flow cytometry assessment of apoptosis extent induced in human breast cancer cell lines
    • S Serrano MJ, Sanchez-Rovira P, Algarra I, et al: Evaluation of a gemcitabine-doxorubicin-paclitaxel combination schedule through flow cytometry assessment of apoptosis extent induced in human breast cancer cell lines. Jpn J Cancer Res 93: 559-566, 2002.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 559-566
    • S Serrano, M.J.1    Sanchez-Rovira, P.2    Algarra, I.3
  • 21
    • 0036860304 scopus 로고    scopus 로고
    • In vitro comparative evaluation of trastuzumab (Herceptin®) combined with paclitaxel (Taxol®) or docetaxel (Taxotere®) in HER2-expressing human breast cancer cell lines
    • DOI 10.1093/annonc/mdf263
    • Merlin JL, Barberi-Heyob M and Bachman N: In vitro comparative evaluation of trastuzumab (Herceptin®) combined with paclitaxel (Taxol®) or docetaxel (Taxotere®) in HER2-expressing human breast cancer cell lines. Ann Oncol 13: 1743-748, 2002. (Pubitemid 35439454)
    • (2002) Annals of Oncology , vol.13 , Issue.11 , pp. 1743-1748
    • Merlin, J.-L.1    Barberi-Heyob, M.2    Bachmann, N.3
  • 24
    • 0033529495 scopus 로고    scopus 로고
    • Cell stress and MKK6b-mediated p38MAP kinase activation inhibit tumor necrosis factor-induced IκB phosphorylation and NF-κB activation
    • Alpert D, Schwenger P, Han J, et al: Cell stress and MKK6b-mediated p38MAP kinase activation inhibit tumor necrosis factor-induced IκB phosphorylation and NF-κB activation. J Biol Chem 274: 22176-22183, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 22176-22183
    • Alpert, D.1    Schwenger, P.2    Han, J.3
  • 26
    • 2142717282 scopus 로고    scopus 로고
    • Sodium salicylate inhibits expression of COX-2 through suppression of ERK and subsequent NF-κB activation in rat ventricular cardiomyocytes
    • Kwon KS and Chae HJ: Sodium salicylate inhibits expression of COX-2 through suppression of ERK and subsequent NF-κB activation in rat ventricular cardiomyocytes. Arch Pharm Res 26: 545-553, 2003.
    • (2003) Arch Pharm Res , vol.26 , pp. 545-553
    • Kwon, K.1    Chae, H.J.2
  • 27
    • 34249089950 scopus 로고    scopus 로고
    • Akt/cAMP-responsive element binding protein/cyclin D1 network: A novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by nexrutine, a Phellodendron amurense bark extract
    • DOI 10.1158/1078-0432.CCR-06-2974
    • Kumar AP, Bhaskaran S, Ganapathy M, et al: Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract. Clin Cancer Res 13: 2784-2794, 2007. (Pubitemid 46788048)
    • (2007) Clinical Cancer Research , vol.13 , Issue.9 , pp. 2784-2794
    • Kumar, A.P.1    Bhaskaran, S.2    Ganapathy, M.3    Crosby, K.4    Davis, M.D.5    Kochunov, P.6    Schoolfield, J.7    Yeh, I.-T.8    Troyer, D.A.9    Ghosh, R.10
  • 28
    • 36048968158 scopus 로고    scopus 로고
    • Regulation of Cox-2 by cyclic AMP response element binding protein in prostate cancer: Potential role for nexrutine
    • DOI 10.1593/neo.07502
    • Ghosh R, Garcia GE, Crosby K, et al: Regulation of Cox-2 by cyclic AMP response element binding protein in prostate cancer: potential role for nexrutine. Neoplasia 9: 893-899, 2007. (Pubitemid 350086434)
    • (2007) Neoplasia , vol.9 , Issue.11 , pp. 893-899
    • Ghosh, R.1    Garcia, G.E.2    Crosbyy, K.3    Inouez, H.4    Thompson, I.M.5    Troyer, D.A.6    Kumar, A.P.7
  • 29
    • 0035163198 scopus 로고    scopus 로고
    • Multiple signaling pathways regulate NF-κB-dependent transcription of the monocyte chemoattractant protein-1 gene in primary endothelial cells
    • Goebeler M, Gillitzer R, Kilian K, et al: Multiple signaling pathways regulate NF-κB-dependent transcription of the monocyte chemoattractant protein-1 gene in primary endothelial cells. Blood 97: 46-55, 2001.
    • (2001) Blood , vol.97 , pp. 46-55
    • Goebeler, M.1    Gillitzer, R.2    Kilian, K.3
  • 30
    • 0033565763 scopus 로고    scopus 로고
    • Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling
    • van Hogerlinden M, Rozell BL and Ahrlund-Richter L, et al: Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling. Cancer Res 59: 3299-3303, 1999.
    • (1999) Cancer Res , vol.59 , pp. 3299-3303
    • Van Hogerlinden, M.1    Rozell, B.L.2    Ahrlund-Richter, L.3
  • 31
    • 0028557348 scopus 로고
    • Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappaB
    • Miyamoto S, Maki M, Schmitt MJ, et al: Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappaB. Proc Natl Acad Sci USA 91: 12740-12744, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12740-12744
    • Miyamoto, S.1    Maki, M.2    Schmitt, M.J.3
  • 32
    • 34547620166 scopus 로고    scopus 로고
    • Identification of the distinct promoters for the two transcripts of apoptosis related protein 3 and their transcriptional regulation by NFAT and NFkappaB
    • DOI 10.1007/s11010-007-9440-7
    • Yang G, Yu F, Fu H, et al: Identification of the distinct promoters for the two transcripts of apoptosis related protein 3 and their transcriptional regulation by NFAT and NFkappaB. Mol Cell Biochem 302: 187-194, 2007. (Pubitemid 47202334)
    • (2007) Molecular and Cellular Biochemistry , vol.302 , Issue.1-2 , pp. 187-194
    • Yang, G.1    Yu, F.2    Fu, H.3    Lu, F.4    Huang, B.5    Bai, L.6    Zhao, Z.7    Yao, L.8    Lu, Z.9
  • 34
    • 19344367506 scopus 로고    scopus 로고
    • Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression
    • DOI 10.1016/j.canlet.2004.10.051, PII S0304383504008754
    • Notarbartolo M, Poma P, Perri D, et al: Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-κB activation levels and in IAP gene expression. Cancer Lett 224: 53-65, 2005. (Pubitemid 40720367)
    • (2005) Cancer Letters , vol.224 , Issue.1 , pp. 53-65
    • Notarbartolo, M.1    Poma, P.2    Perri, D.3    Dusonchet, L.4    Cervello, M.5    D'Alessandro, N.6
  • 35
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, et al: NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281: 1680-1683, 1998.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3
  • 36
    • 0035966071 scopus 로고    scopus 로고
    • NF-kappaB activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells
    • Bian X, McAllister-Lucas LM, Shao F, et al: NF-kappaB activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells. J Biol Chem 276: 48921-48929, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 48921-48929
    • Bian, X.1    McAllister-Lucas, L.M.2    Shao, F.3
  • 37
    • 0034689773 scopus 로고    scopus 로고
    • Role of NF-kappaB in p53-mediated programmed cell death
    • DOI 10.1038/35009130
    • Ryan KM, Ernst MK, Rice NR, et al: Role of NF-kappaB in p53-mediated programmed cell death. Nature 404: 892-897, 2000. (Pubitemid 30230343)
    • (2000) Nature , vol.404 , Issue.6780 , pp. 892-897
    • Ryan, K.M.1    Ernst, M.K.2    Rice, N.R.3    Vousden, K.H.4
  • 38
    • 0033553421 scopus 로고    scopus 로고
    • Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells
    • Ivanov VN and Ronai Z: Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells. J Biol Chem 274: 14079-14089, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 14079-14089
    • Ivanov, V.1    Ronai, Z.2
  • 41
    • 0030991201 scopus 로고    scopus 로고
    • The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP- Independent mechanism
    • Zhong H, SuYang H, Erdjument-Bromage H, et al: The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP- independent mechanism. Cell 89: 413-424, 1997.
    • (1997) Cell , vol.89 , pp. 413-424
    • Zhong, H.1    SuYang, H.2    Erdjument-Bromage, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.