메뉴 건너뛰기




Volumn 20, Issue 13, 2000, Pages 4680-4690

Distinct pathways of cell migration and antiapoptotic response to epithelial injury: Structure-function analysis of human intestinal trefoil factor

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; EPIDERMAL GROWTH FACTOR RECEPTOR; INTESTINAL TREFOIL FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEINASE; SERINE;

EID: 0034042831     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.13.4680-4690.2000     Document Type: Article
Times cited : (195)

References (59)
  • 1
    • 0028935754 scopus 로고
    • Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor, and transforming growth factor alpha mRNAs in rat stomach
    • Alison, M. R., R. Chinery, R. Poulsom, P. Ashwood, J. M. Longcroft, and N. A. Wright. 1995. Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor, and transforming growth factor alpha mRNAs in rat stomach. J. Pathol. 175:405-414.
    • (1995) J. Pathol. , vol.175 , pp. 405-414
    • Alison, M.R.1    Chinery, R.2    Poulsom, R.3    Ashwood, P.4    Longcroft, J.M.5    Wright, N.A.6
  • 2
    • 0343334395 scopus 로고    scopus 로고
    • Oral trefoil peptide protect against ethanol- and indomethacin-induced gastric injury in rats
    • Babyatsky, M. W., M. deBeaumont, L. Thim, and D. K. Podolsky. 1996. Oral trefoil peptide protect against ethanol- and indomethacin-induced gastric injury in rats. Gastroenterology 105:1323-1332.
    • (1996) Gastroenterology , vol.105 , pp. 1323-1332
    • Babyatsky, M.W.1    Debeaumont, M.2    Thim, L.3    Podolsky, D.K.4
  • 3
    • 0028209868 scopus 로고
    • Solution structure of a trefoil-motif-containing cell growth factor, porcine spasmolytic protein
    • Carr, M., C. J. Bauer, M. J. Gradwell, and J. Feeney. 1994. Solution structure of a trefoil-motif-containing cell growth factor, porcine spasmolytic protein. Proc. Natl. Acad. Sci. USA 91:2206-2210.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2206-2210
    • Carr, M.1    Bauer, C.J.2    Gradwell, M.J.3    Feeney, J.4
  • 4
    • 0002949164 scopus 로고
    • Epidermal growth factor protects epithelial cells against Fas-induced apoptosis
    • Chen, P., H. Xie, M. Sekar, K. Gupta, and A. Wells. 1994. Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. J. Biol. Chem. 274:17612-17618.
    • (1994) J. Biol. Chem. , vol.274 , pp. 17612-17618
    • Chen, P.1    Xie, H.2    Sekar, M.3    Gupta, K.4    Wells, A.5
  • 5
    • 0029038880 scopus 로고
    • Immunoprecipitation and characterization of a binding protein specific for the peptide, intestinal trefoil factor
    • Chinery, R., and H. M. Cox. 1995. Immunoprecipitation and characterization of a binding protein specific for the peptide, intestinal trefoil factor. Peptides 16:749-755.
    • (1995) Peptides , vol.16 , pp. 749-755
    • Chinery, R.1    Cox, H.M.2
  • 6
    • 0028946839 scopus 로고
    • Mutually exclusive interactions between factors binding to adjacent sp1 and AT-rich elements regulate gastrin gene transcription in insulinoma cells
    • Chung, D. C., S. J. Brand, and L. G. Tillotson. 1995. Mutually exclusive interactions between factors binding to adjacent Sp1 and AT-rich elements regulate gastrin gene transcription in insulinoma cells. J. Biol. Chem. 270: 8829-8836.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8829-8836
    • Chung, D.C.1    Brand, S.J.2    Tillotson, L.G.3
  • 7
    • 0027160764 scopus 로고
    • Transforming growth factor beta regulation of migration in wounded rat intestinal epithelial monolayers
    • Ciacci, C., S. E. Lind, and D. K. Podolsky. 1993. Transforming growth factor beta regulation of migration in wounded rat intestinal epithelial monolayers. Gastroenterology 105:93-101.
    • (1993) Gastroenterology , vol.105 , pp. 93-101
    • Ciacci, C.1    Lind, S.E.2    Podolsky, D.K.3
  • 9
    • 0028360991 scopus 로고
    • Trefoil peptides promote epithelial migration through a TGF-β independent pathway
    • Dignass, A. U., K. Lynch-Devaney, H. Kindon, L. Thim, and D. K. Podolsky. 1994. Trefoil peptides promote epithelial migration through a TGF-β independent pathway. J. Clin. Investig. 94:376-383.
    • (1994) J. Clin. Investig. , vol.94 , pp. 376-383
    • Dignass, A.U.1    Lynch-Devaney, K.2    Kindon, H.3    Thim, L.4    Podolsky, D.K.5
  • 10
    • 0028095407 scopus 로고
    • Hepatocyte growth factor/scatter factor modulate intestinal epithelial cell proliferation and migration
    • Dignass, A. U., K. Lynch-Devaney, and D. K. Podolsky. 1994. Hepatocyte growth factor/scatter factor modulate intestinal epithelial cell proliferation and migration. Biochem. Biophys. Res. Commun. 202:701-709.
    • (1994) Biochem. Biophys. Res. Commun. , vol.202 , pp. 701-709
    • Dignass, A.U.1    Lynch-Devaney, K.2    Podolsky, D.K.3
  • 11
    • 0027436376 scopus 로고
    • Cytokine modulation of intestinal epithelial cell restitution: Central role of transforming growth factor-β
    • Dignass, A. U., and D. K. Podolsky. 1993. Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor-β. Gastroenterology 105:1323-1332.
    • (1993) Gastroenterology , vol.105 , pp. 1323-1332
    • Dignass, A.U.1    Podolsky, D.K.2
  • 12
    • 0028231686 scopus 로고
    • Fibroblast growth factors modulate intestinal epithelial cell growth and migration
    • Dignass, A. U., S. Tsunekawa, and D. K. Podolsky. 1994. Fibroblast growth factors modulate intestinal epithelial cell growth and migration. Gastroenterology 106:1254-1262.
    • (1994) Gastroenterology , vol.106 , pp. 1254-1262
    • Dignass, A.U.1    Tsunekawa, S.2    Podolsky, D.K.3
  • 14
    • 0033580853 scopus 로고    scopus 로고
    • Epidermal growth factor protects epithelial cells against Fas-induced apoptosis
    • Gibson, S., S. Tu, R. Oyer, S. M. Anderson, and G. L. Johnson. 1999. Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. J. Biol. Chem. 274:17612-17618.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17612-17618
    • Gibson, S.1    Tu, S.2    Oyer, R.3    Anderson, S.M.4    Johnson, G.L.5
  • 15
    • 0029741102 scopus 로고    scopus 로고
    • Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation
    • Gilmore, A. P., and L. H. Romer. 1996. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol. Cell. Biol. 7:1209-1224.
    • (1996) Mol. Cell. Biol. , vol.7 , pp. 1209-1224
    • Gilmore, A.P.1    Romer, L.H.2
  • 16
    • 0020085354 scopus 로고
    • Pancreatic spasmolytic polypeptide (PSP). I. Preparation and initial chemical characterization of a new polypeptide from porcine pancreas
    • Jørgensen, K. H., L. Thim, and H. E. Jacobsen. 1982. Pancreatic spasmolytic polypeptide (PSP). I. Preparation and initial chemical characterization of a new polypeptide from porcine pancreas. Regul. Pept. 3:207-219.
    • (1982) Regul. Pept. , vol.3 , pp. 207-219
    • Jørgensen, K.H.1    Thim, L.2    Jacobsen, H.E.3
  • 17
    • 0031915586 scopus 로고    scopus 로고
    • Intestinal trefoil factor induces inactivation of extracellular signal-related protein kinases in intestinal epithelial cells
    • Kanai, M., and D. K. Podolsky. 1997. Intestinal trefoil factor induces inactivation of extracellular signal-related protein kinases in intestinal epithelial cells. Proc. Natl. Acad. Sci. USA 95:178-182.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 178-182
    • Kanai, M.1    Podolsky, D.K.2
  • 19
    • 0032563207 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway
    • Khwaja, A., K. Lehmann, B. M. Marte, and J. Downward. 1998. Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway. J. Biol. Chem. 273:18793-18801.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18793-18801
    • Khwaja, A.1    Lehmann, K.2    Marte, B.M.3    Downward, J.4
  • 20
    • 0029133784 scopus 로고
    • Trefoil peptide protection of intestinal epithelial barrier function: Cooperative interaction with mucin glycoprotein
    • Kindon, H., C. Pothoulakis, L. Thim, K. Lynch-Devaney, and D. K. Podolsky. 1995. Trefoil peptide protection of intestinal epithelial barrier function: cooperative interaction with mucin glycoprotein. Gastroenterology 109:516-523.
    • (1995) Gastroenterology , vol.109 , pp. 516-523
    • Kindon, H.1    Pothoulakis, C.2    Thim, L.3    Lynch-Devaney, K.4    Podolsky, D.K.5
  • 23
    • 0021256117 scopus 로고
    • Amplification and purification of plasmid-encoded thioredoxin from Escherichia coli K12
    • Lunn, C. A., S. Kathju, B. J. Wallace, S. R. Kushner, and V. Pigiet. 1984. Amplification and purification of plasmid-encoded thioredoxin from Escherichia coli K12. J. Biol. Chem. 259:10469-10474.
    • (1984) J. Biol. Chem. , vol.259 , pp. 10469-10474
    • Lunn, C.A.1    Kathju, S.2    Wallace, B.J.3    Kushner, S.R.4    Pigiet, V.5
  • 24
    • 0031813248 scopus 로고    scopus 로고
    • Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects
    • Marchbank, T., B. R. Westley, F. E. B. May, D. P. Calman, and R. J. Playford. 1998. Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects. J. Pathol. 185:153-158.
    • (1998) J. Pathol. , vol.185 , pp. 153-158
    • Marchbank, T.1    Westley, B.R.2    May, F.E.B.3    Calman, D.P.4    Playford, R.J.5
  • 25
    • 0029828745 scopus 로고    scopus 로고
    • Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor
    • Mashimo, H., D.-C. Wu, D. K. Podolsky, and M. C. Fishman. 1996. Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science 274:262-265.
    • (1996) Science , vol.274 , pp. 262-265
    • Mashimo, H.1    Wu, D.-C.2    Podolsky, D.K.3    Fishman, M.C.4
  • 26
    • 0025823006 scopus 로고
    • Radioautographic localization of epidermal growth factor receptors in human fetal gut
    • Menard, D., and P. Pothier. 1991. Radioautographic localization of epidermal growth factor receptors in human fetal gut. Gastroenterology 101:640-649.
    • (1991) Gastroenterology , vol.101 , pp. 640-649
    • Menard, D.1    Pothier, P.2
  • 27
    • 0032538798 scopus 로고    scopus 로고
    • Integrins induce activation of EGF receptor: Role in MAP kinase induction and adhesion-dependent cell survival
    • Moro, L., M. Venturino, C. Bozzo, L. Silengo, F. Altruda, L. Beguinot, G. Tarone, and P. Defilippi. 1998. Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival. EMBO. J. 17:6622-6633.
    • (1998) EMBO. J. , vol.17 , pp. 6622-6633
    • Moro, L.1    Venturino, M.2    Bozzo, C.3    Silengo, L.4    Altruda, F.5    Beguinot, L.6    Tarone, G.7    Defilippi, P.8
  • 28
    • 0033549558 scopus 로고    scopus 로고
    • Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner
    • Nguyen, D. H., A. D. Catling, D. J. Webb, M. Sankovie, L. A. Walker, A. V. Somlyo, M. J. Weber, and S. L. Gonias. 1999. Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner. J. Cell Biol. 146:149-164.
    • (1999) J. Cell Biol. , vol.146 , pp. 149-164
    • Nguyen, D.H.1    Catling, A.D.2    Webb, D.J.3    Sankovie, M.4    Walker, L.A.5    Somlyo, A.V.6    Weber, M.J.7    Gonias, S.L.8
  • 29
    • 0026254543 scopus 로고
    • Rapid and efficient cloning of Alu-PCR products using uracil DNA glycosylase
    • Nisson, P. E., A. Rashtchain, and P. C. Watkins. 1991. Rapid and efficient cloning of Alu-PCR products using uracil DNA glycosylase. PCR Methods Appl. 1:120-123.
    • (1991) PCR Methods Appl. , vol.1 , pp. 120-123
    • Nisson, P.E.1    Rashtchain, A.2    Watkins, P.C.3
  • 30
    • 0026691975 scopus 로고
    • Intestinal epithelial restitution: Characterization of a cell culture model and mapping of cytoskeletal elements in migrating cells
    • Nusrat, A., C. Delp, and J. L. Madara. 1992. Intestinal epithelial restitution: characterization of a cell culture model and mapping of cytoskeletal elements in migrating cells. J. Clin. Investig. 89:1501-1511.
    • (1992) J. Clin. Investig. , vol.89 , pp. 1501-1511
    • Nusrat, A.1    Delp, C.2    Madara, J.L.3
  • 31
    • 0028349254 scopus 로고
    • Hepatocyte growth factor/scatter factor effects on epithelial cells: Regulation of intercellular junctions in transformed and non-transformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and induction of rapid wound repair in a transformed model epithelium
    • Nusrat, A., C. Parkos, A. Bacarra, P. Godowski, C. Delp-Archer, C. Rosen, and J. Madara. 1994. Hepatocyte growth factor/scatter factor effects on epithelial cells: regulation of intercellular junctions in transformed and non-transformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and induction of rapid wound repair in a transformed model epithelium. J. Clin. Investig. 93:2056-2065.
    • (1994) J. Clin. Investig. , vol.93 , pp. 2056-2065
    • Nusrat, A.1    Parkos, C.2    Bacarra, A.3    Godowski, P.4    Delp-Archer, C.5    Rosen, C.6    Madara, J.7
  • 33
    • 0027415669 scopus 로고
    • Identification of human intestinal trefoil factor: Goblet cell-specific expression of a peptide targeted for apical secretion
    • Podolsky, D. K., K. Lynch-Devaney, J. L. Stow, P. Oates, B. Murgue, M. deBeaumont, B. E. Sands, and Y. R. Mahida. 1993. Identification of human intestinal trefoil factor: goblet cell-specific expression of a peptide targeted for apical secretion. J. Biol. Chem. 268:6694-6702.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6694-6702
    • Podolsky, D.K.1    Lynch-Devaney, K.2    Stow, J.L.3    Oates, P.4    Murgue, B.5    DeBeaumont, M.6    Sands, B.E.7    Mahida, Y.R.8
  • 34
    • 0028879818 scopus 로고
    • NMR-based structural studies of the pNR-2/pS2 single domain trefoil peptide. Similarities to porcine spasmolytic peptide and evidence for a monomeric structure
    • Polshakov, V. I., T. A. Frenkiel, B. Westley, M. Chadwick, F. May, M. D. Carr, and J. Feeney. 1995. NMR-based structural studies of the pNR-2/pS2 single domain trefoil peptide. Similarities to porcine spasmolytic peptide and evidence for a monomeric structure. Eur. J. Biochem. 233:847-855.
    • (1995) Eur. J. Biochem. , vol.233 , pp. 847-855
    • Polshakov, V.I.1    Frenkiel, T.A.2    Westley, B.3    Chadwick, M.4    May, F.5    Carr, M.D.6    Feeney, J.7
  • 36
    • 4244188311 scopus 로고
    • Trefoil peptides: A newly recognized family of epithelial mucin-associated molecules
    • Poulsom, R., and N. A. Wright. 1993. Trefoil peptides: a newly recognized family of epithelial mucin-associated molecules. Am. J. Physiol. 272:G1540-G1549.
    • (1993) Am. J. Physiol. , vol.272
    • Poulsom, R.1    Wright, N.A.2
  • 37
    • 85045496522 scopus 로고
    • A novel method for site-directed mutagenesis using PCR and uracil DNA glycosylase
    • Rashtchian, A., C. G. Thornton, and G. Heidecker. 1992. A novel method for site-directed mutagenesis using PCR and uracil DNA glycosylase. PCR Methods Appl. 2:124-130.
    • (1992) PCR Methods Appl. , vol.2 , pp. 124-130
    • Rashtchian, A.1    Thornton, C.G.2    Heidecker, G.3
  • 38
    • 0033516666 scopus 로고    scopus 로고
    • Protein kinase C δ is essential for etoposide-induced apoptosis in salivary gland acinar cells
    • Reyland, M. E., S. M. Anderson, A. A. Matassa, K. A. Barzen, and D. O. Quissell. 1999. Protein kinase C δ is essential for etoposide-induced apoptosis in salivary gland acinar cells. J. Biol. Chem. 274:19115-19123.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19115-19123
    • Reyland, M.E.1    Anderson, S.M.2    Matassa, A.A.3    Barzen, K.A.4    Quissell, D.O.5
  • 42
    • 0031921101 scopus 로고    scopus 로고
    • Multiple grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: Summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events
    • Schlaepfer, D. D., K. C. Jones, and T. Hunter. 1998. Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol. Cell. Biol. 18:2571-2585.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2571-2585
    • Schlaepfer, D.D.1    Jones, K.C.2    Hunter, T.3
  • 43
    • 0027522922 scopus 로고
    • Redistribution of epidermal growth factor receptor as a function of cell density, cell-cell adhesion and calcium in human (A-431) cells
    • Suarez-Quian, C. A., and S. W. Byers. 1993. Redistribution of epidermal growth factor receptor as a function of cell density, cell-cell adhesion and calcium in human (A-431) cells. Tissue Cell 25:1-17.
    • (1993) Tissue Cell , vol.25 , pp. 1-17
    • Suarez-Quian, C.A.1    Byers, S.W.2
  • 44
    • 0027391509 scopus 로고
    • Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility
    • Takaishi, K., A. Kikuchi, S. Kuroda, K. Kotani, T. Sasaki, and Y. Takai. 1993. Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility. Mol. Cell. Biol. 13:72-79.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 72-79
    • Takaishi, K.1    Kikuchi, A.2    Kuroda, S.3    Kotani, K.4    Sasaki, T.5    Takai, Y.6
  • 45
    • 0031589536 scopus 로고    scopus 로고
    • Characterization of a putative receptor for intestinal trefoil factor in rat small intestine: Identification by in situ binding and ligand blotting
    • Tan, X.-D., W. Hsueh, H. Chang, K.-R. Wei, and F. Gonzalez-Crussi. 1997. Characterization of a putative receptor for intestinal trefoil factor in rat small intestine: identification by in situ binding and ligand blotting. Biochem. Biophys. Res. Commun. 237:673-677.
    • (1997) Biochem. Biophys. Res. Commun. , vol.237 , pp. 673-677
    • Tan, X.-D.1    Hsueh, W.2    Chang, H.3    Wei, K.-R.4    Gonzalez-Crussi, F.5
  • 46
    • 0032960673 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation regulates intestinal epithelial differentiation
    • Taupin, D. R., and D. K. Podolsky. 1999. Mitogen-activated protein kinase activation regulates intestinal epithelial differentiation. Gastroenterology 116:1072-1080.
    • (1999) Gastroenterology , vol.116 , pp. 1072-1080
    • Taupin, D.R.1    Podolsky, D.K.2
  • 47
    • 0033134603 scopus 로고    scopus 로고
    • The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor- and MAP kinase-dependent interregulation
    • Taupin, D. R., D. C. Wu, W. K. Jeon, K. Devaney, T. C. Wang, and D. K. Podolsky. 1999. The trefoil gene family are coordinately expressed immediate-early genes: EGF receptor- and MAP kinase-dependent interregulation. J. Clin. Investig. 103:R31-R38.
    • (1999) J. Clin. Investig. , vol.103
    • Taupin, D.R.1    Wu, D.C.2    Jeon, W.K.3    Devaney, K.4    Wang, T.C.5    Podolsky, D.K.6
  • 48
    • 0034681162 scopus 로고    scopus 로고
    • Intestinal trefoil factor confers colonic epithelial resistance to apoptosis
    • Taupin, D. R., K. Kinoshita, and D. K. Podolsky. 2000. Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. Proc. Natl. Acad. Sci. USA 97:799-804.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 799-804
    • Taupin, D.R.1    Kinoshita, K.2    Podolsky, D.K.3
  • 49
    • 0024349761 scopus 로고
    • A new family of growth factor-like peptides. 'Trefoil' disulfide loop structures as a common feature in breast cancer associated peptide (pS2), pancreatic spasmolytic polypeptide (PSP), and frog skin peptides (spasmolysins)
    • Thim, L. 1989. A new family of growth factor-like peptides. 'Trefoil' disulfide loop structures as a common feature in breast cancer associated peptide (pS2), pancreatic spasmolytic polypeptide (PSP), and frog skin peptides (spasmolysins). FEBS. Lett. 250:85-90.
    • (1989) FEBS. Lett. , vol.250 , pp. 85-90
    • Thim, L.1
  • 52
    • 0002934088 scopus 로고    scopus 로고
    • Trefoil peptide TFF2 (spasmolytic polypeptide) potently accelerates healing and reduces inflammation in a rat model of colitis
    • Tran, C. P., G. A. Cook, N. D. Yeomans, L. Thim, and A. S. Giraud. 1999. Trefoil peptide TFF2 (spasmolytic polypeptide) potently accelerates healing and reduces inflammation in a rat model of colitis. Gut 44:636-642.
    • (1999) Gut , vol.44 , pp. 636-642
    • Tran, C.P.1    Cook, G.A.2    Yeomans, N.D.3    Thim, L.4    Giraud, A.S.5
  • 53
    • 0030483560 scopus 로고    scopus 로고
    • Expression of a truncated EGF receptor is associated with inhibition of pancreatic cell growth and enhanced sensitivity to cisplatinum
    • Wagner, M., T. Cao, M. E. Lopez, C. Hope, K. van Nostrand, M. S. Kobrin, H. U. Fan, M. W. Buchler, and M. Korc. 1996. Expression of a truncated EGF receptor is associated with inhibition of pancreatic cell growth and enhanced sensitivity to cisplatinum. Int. J. Cancer 68:782-787.
    • (1996) Int. J. Cancer , vol.68 , pp. 782-787
    • Wagner, M.1    Cao, T.2    Lopez, M.E.3    Hope, C.4    Van Nostrand, K.5    Kobrin, M.S.6    Fan, H.U.7    Buchler, M.W.8    Korc, M.9
  • 54
    • 0031782321 scopus 로고    scopus 로고
    • Activation of Ras/Mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation
    • Walker, F., A. Kato, L. J. Gonez, M. L. Hibbs, N. Pouliot, A. Levitzki, and A. W. Burgess. 1998. Activation of Ras/Mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation. Mol. Cell. Biol. 18:7192-7204.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7192-7204
    • Walker, F.1    Kato, A.2    Gonez, L.J.3    Hibbs, M.L.4    Pouliot, N.5    Levitzki, A.6    Burgess, A.W.7
  • 55
    • 0022467933 scopus 로고
    • Location of epidermal growth factor receptors on porcine thyroid follicle cells and receptor regulation by thyrotropin
    • Westermark, K., B. Westermark, F. A. Karlsson, and L. E. Ericson. 1986. Location of epidermal growth factor receptors on porcine thyroid follicle cells and receptor regulation by thyrotropin. Endocrinology 118:1040-1046.
    • (1986) Endocrinology , vol.118 , pp. 1040-1046
    • Westermark, K.1    Westermark, B.2    Karlsson, F.A.3    Ericson, L.E.4
  • 56
    • 0030949116 scopus 로고    scopus 로고
    • Rolling in the clover: Trefoil factor family (TFF)-domain peptides, cell migration and cancer
    • Wright, N. A., W. Hoffmann, W. R. Otto, M. C. Rio, and L. Thim. 1997. Rolling in the clover: trefoil factor family (TFF)-domain peptides, cell migration and cancer. FEBS Lett. 408:121-123.
    • (1997) FEBS Lett. , vol.408 , pp. 121-123
    • Wright, N.A.1    Hoffmann, W.2    Otto, W.R.3    Rio, M.C.4    Thim, L.5
  • 59
    • 0032990608 scopus 로고    scopus 로고
    • Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes
    • Zeigler, M. E., Y. Chi, T. Schmidt, and J. Varani. 1999. Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes. J. Cell. Physiol. 180:271-284.
    • (1999) J. Cell. Physiol. , vol.180 , pp. 271-284
    • Zeigler, M.E.1    Chi, Y.2    Schmidt, T.3    Varani, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.