COMT Val158Met polymorphism modulates cognitive effects of dietary intervention

Frontiers in Aging Neuroscience

Volumn 2, Issue NOV, 2010, Pages

  Witte, Anja Veronica ^a   Jansen, Stefanie ^b   Schirmacher, Anja ^b   Young, Peter ^b   Flöel, Agnes ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Aging; Cognition; COMT; Diet; Genetic variation; Memory

Indexed keywords

EID: 79960715740     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2010.00146     Document Type: Article

References (46)

1. Backman, L., Ginovart, N., Dixon, R. A., Wahlin, T. B., Wahlin, A., Halldin, C., and Farde, L. (2000). Age-related cognitive deficits mediated by changes in the striatal dopamine system. Am. J. Psychiatry 157, 635-637.
2. Barnett, J. H., Scoriels, L., and Munafò, M. R. (2008). Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108met polymorphism. Biol. Psychiatry 64, 137-144.
3. Bertolino, A., Rubino, V., Sambataro, F., Blasi, G., Latorre, V., Fazio, L., Caforio, G., Petruzzella, V., Kolachana, B., Hariri, A., Meyer-Lindenberg, A., Nardini, M., Weinberger, D. R., and Scarabino, T. (2006). Prefrontal-hippocampal coupling during memory processing is modulated by COMT val158met genotype. Biol. Psychiatry 60, 1250-1258.
4. Corneveaux, J. J., Liang, W. S. , Reiman, E. M., Webster, J. A., Myers, A. J., Zismann, V. L., Joshipura, K. D., Pearson, J. V., Hu-Lince, D., Craig, D. W., Coon, K. D., Dunckley, T., Bandy, D., Lee, W., Chen, K., Beach, T. G., Mastroeni, D., Grover, A., Ravid, R., Sando, S. B., Aasly, J. O., Heun, R., Jessen, F., Kölsch, H., Rogers, J., Hutton, M. L., Melquist, S., Petersen, R. C., Alexander, G. E., Caselli, R. J., Papassotiropoulos, A., Stephan, D. A., and Huentelman, M. J. (2010). Evidence for an association between KIBRA and late-onset Alzheimer's disease. Neurobiol. Aging 31, 901-909.
5. de Frias, C. M., Annerbrink, K., Westberg, L., Eriksson, E., Adolfsson, R., and Nilsson, L.-G. (2004). COMT gene polymorphism is associated with declarative memory in adulthood and old age. Behav. Genet. 34, 533-539.
6. Diaz-Asper, C. M., Weinberger, D. R., and Goldberg, T. E. (2006). Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeutics. NeuroRx 3, 97-105.
7. Dore, G. A., Elias, M. F., Robbins, M. A., Elias, P. K., and Nagy, Z. (2009). Presence of the APOE epsilon4 allele modifies the relationship between type 2 diabetes and cognitive performance: the Maine-Syracuse Study. Diabetologia 52, 2551-2560.
8. Egan, M. F., Goldberg, T. E., Kolachana, B. S., Callicott, J. H., Mazzanti, C. M., Straub, R. E., Goldman, D., and Weinberger, D. R. (2001). Effect of COMT val108/158 met genotype on frontal lobe function and risk for schizophrenia. Proc. Natl. Acad. Sci. U.S.A. 98, 6917-6922.
9. Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D., Dean, M., Lu, B., and Weinberger, D. R. (2003). The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112, 257-269.
10. Enoch, M. A., Waheed, J. F., Harris, C. R., Albaugh, B., and Goldman, D. (2009). COMT val158met and cognition: main effects and interaction with educational attainment. Genes Brain Behav. 8, 36-42.
11. Erixon-Lindroth, N., Farde, L., Wahlin, T. B., Sovago, J., Halldin, C., and Backman, L. (2005). The role of the striatal dopamine transporter in cognitive aging. Psychiatry Res. 138, 1-12.
12. Giakoumaki, S. G., Roussos, P., and Bitsios, P. (2008). Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism. Neuropsychopharmacology 33, 3058-3068.
13. Goldberg, T. E., and Weinberger, D. R. (2004). Genes and the parsing of cognitive processes. Trends Cogn. Sci. (Regul. Ed.) 8, 325-335.
14. Goldman, D., Weinberger, D. R., Malhotra, A. K., and Goldberg, T. E. (2009). The role of COMT val158met in cognition. Biol. Psychiatry 65, e3-e4.
15. Gomez-Pinilla, F. (2008). The influences of diet and exercise on mental health through hormesis. Ageing Res. Rev. 7, 49-62.
16. Helmstaedter, C., and Kurthen, M. (2001). Memory and epilepsy: characteristics, course, and influence of drugs and surgery. Curr. Opin. Neurol. 14, 211-216.
17. Hochhaus, L. (1972). A table for the calculation of d' and beta. Psychol. Bull. 77, 375-376.
18. Hong, C. C., Thompson, H. J., Jiang, C., Hammond, G. L., Tritchler, D., Yaffe, M., and Boyd, N. F. (2003). Val158met Polymorphism in catechol-O-methyltransferase gene associated with risk factors for breast cancer. Cancer Epidemiol. Biomarkers Prev. 12, 838-847.
19. Hong, J., Shu-Leong, H., Tao, X., and Lap-Ping, Y. (1998). Distribution of catechol-O-methyltransferase expression in human central nervous system. Neuroreport 9, 2861-2864.
20. Krach, S., Jansen, A., Krug, A., Markov, V., Thimm, M., Sheldrick, A. J., Eggermann, T., Zerres, K., Stöcker, T., Shah, N. J., and Kircher, T. (2010). COMT genotype and its role on hippocampal-prefrontal regions in declarative memory. Neuroimage 53, 978-984.
21. Lewis, D. A., Melchitzky, D. S., Sesack, S. R., Whitehead, R. E., Auh, S., and Sampson, A. (2001). Dopamine transporter immunoreactivity in monkey cerebral cortex: regional, laminar, and ultrastructural localization. J. Comp. Neurol. 432, 119-136.
22. Lindenberger, U., Nagel, I. E., Chicherio, C., Li, S. C., Heekeren, H. R., and Backman, L. (2008). Age-related decline in brain resources modulates genetic effects on cognitive functioning. Front. Neurosci. 2, 234-244. doi: 10.3389/neuro.01.039.2008.
23. Lotta, T., Vidgren, J., Tilgmann, C., Ulmanen, I., Melén, K., Julkunen, I., and Taskinen, J. (1995). Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 34, 4202-4210.
24. Loughead, J., Wileyto, E. P., Valdez, J. N., Sanborn, P., Tang, K., Strasser, A. A., Ruparel, K., Ray, R., Gur, R. C., and Lerman, C. (2009). Effect of abstinence challenge on brain function and cognition in smokers differs by COMT genotype. Mol. Psychiatry 14, 820-826.
25. Markowitsch, H. J., and Härting, C. (1996). Interdependence of priming performance and brain-damage. Int. J. Neurosci. 85, 291-300.
26. Mata, J., Thompson, R. J., and Gotlib, I. H. (2010). BDNF genotype moderates the relation between physical activity and depressive symptoms. Health Psychol. 29, 130-133.
27. Mattay, V. S., Goldberg, T. E., Fera, F., Hariri, A. R., Tessitore, A., Egan, M. F., Kolachana, B., Callicott, J. H., and Weinberger, D. R. (2003). Catechol O-methyltransferase val158-Met genotype and individual variation in the brain response to amphetamine. Proc. Natl. Acad. Sci. U.S.A. 100, 6186-6191.
28. Mattson, M. P., Maudsley, S., and Martin, B. (2004a). A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin. Ageing Res. Rev. 3, 445-464.
29. Mattson, M. P., Duan, W., Wan, R., and Guo, Z. (2004b). Prophylactic activation of neuroprotective stress response pathways by dietary and behavioral manipulations. NeuroRx 1, 111-116.
30. Mayor, S. (2007). Fitting the drug to the patient. BMJ 334, 452-453.
31. Mazei, M. S., Pluto, C. P., Kirkbride, B., and Pehek, E. A. (2002). Effects of catecholamine uptake blockers in the caudate-putamen and subregions of the medial prefrontal cortex of the rat. Brain Res. 936, 58-67.
32. Meyer-Lindenberg, A., Nichols, T., Callicott, J. H., Ding, J., Kolachana, B., Buckholtz, J., Mattay, V. S., Egan, M., and Weinberger, D. R. (2006). Impact of complex genetic variation in COMT on human brain function. Mol. Psychiatry 11, 867-877.
33. Mier, D., Kirsch, P., and Meyer-Lindenberg, A. (2009). Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis. Mol. Psychiatry. 15, 918-927.
34. Morón, J. A., Brockington, A., Wise, R. A., Rocha, B. A., and Hope, B. T. (2002). Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines. J. Neurosci. 22, 389-395.
35. Nagel, I. E., Chicherio, C., Li, S.-C., von Oertzen, T., Sander, T., Villringer, A., Heekeren, H. R., Bäckman, L., and Lindenberger, U. (2008). Human aging magnifies genetic effects on executive functioning and working memory. Front. Hum. Neurosci. 2, 1. doi: 10.3389/neuro.09.001.2008.
36. Potter, G. G., Taylor, W. D., McQuoid, D. R., Steffens, D. C., Welsh-Bohmer, K. A., and Krishnan, K. R. R. (2009). The COMT Val158Met polymorphism and cognition in depressed and non-depressed older adults. Int. J. Ger. Psychiatry 24, 1127-1133.
37. Raz, N., Rodrigue, K. M., Kennedy, K. M., and Land, S. (2009). Genetic and vascular modifiers of age-sensitive cognitive skills: effects of COMT, BDNF, ApoE, and hypertension. Neuropsychology 23, 105-116.
38. Reitan, R. M., and Herring, S. (1985). A short screening device for identification of cerebral dysfunction in children. J. Clin. Psychol. 41, 643-650.
39. Ritter, S., Dinh, T. T., and Li, A. J. (2006). Hindbrain catecholamine neurons control multiple glucoregulatory responses. Physiol. Behav. 89, 490-500.
40. Shing, Y. L., Werkle-Bergner, M., Brehmer, Y., Muller, V., Li, S. C., and Lindenberger, U. (2010). Episodic memory across the lifespan: the contributions of associative and strategic components. Neurosci. Biobehav. Rev. 34, 1080-1091.
41. Stranahan, A. M., and Mattson, M. P. (2008). Impact of energy intake and expenditure on neuronal plasticity. Neuromolecular Med. 10, 209-218.
42. Strauss, E., Sherman, E. M., and Spreen, O. (2006). A Compendium of Neuropsychological Tests. Administration, Norms, and Commentary. Oxford: Oxford University Press.
43. Volkow, N. D., Gur, R. C., Wang, G. J., Fowler, J. S., Moberg, P. J., Ding, Y. S., Hitzemann, R., Smith, G., and Logan, J. (1998). Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals. Am. J. Psychiatry 155, 344-349.
44. Witte, A. V., Fobker, M., Gellner, R., Knecht, S., and Floel, A. (2009). Caloric restriction improves memory in elderly humans. Proc. Natl. Acad. Sci. U.S.A. 106, 1255-1260.
45. Zhang, H., Kranzler, H. R., Poling, J., Gruen, J. R., and Gelernter, J. (2009). Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use. Neuropsychopharmacology 34, 2508-2516.
46. Zhao, W. Q., Chen, H., Quon, M. J., and Alkon, D. L. (2004). Insulin and the insulin receptor in experimental models of learning and memory. Eur. J. Pharmacol. 490, 71-81.