-
1
-
-
0033516320
-
Colorectal cancer: Molecules and populations
-
Potter JD. (1999) Colorectal cancer: molecules and populations. J. Natl. Cancer Inst. 91:916-32.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 916-932
-
-
Potter, J.D.1
-
2
-
-
0024536654
-
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
-
Baker SJ, et al. (1989) Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science. 244:217-21.
-
(1989)
Science
, vol.244
, pp. 217-221
-
-
Baker, S.J.1
-
3
-
-
0023256456
-
Prevalence of ras gene mutations in human colorectal cancers
-
Bos JL, et al. (1987) Prevalence of ras gene mutations in human colorectal cancers. Nature. 327:293-7.
-
(1987)
Nature
, vol.327
, pp. 293-297
-
-
Bos, J.L.1
-
4
-
-
0025056930
-
Identification of a chromosome 18q gene that is altered in colorectal cancers
-
Fearon ER, et al. (1990) Identification of a chromosome 18q gene that is altered in colorectal cancers. Science. 247:49-56.
-
(1990)
Science
, vol.247
, pp. 49-56
-
-
Fearon, E.R.1
-
5
-
-
0025909734
-
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers
-
Kinzler KW, et al. (1991) Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science. 251:1366-70.
-
(1991)
Science
, vol.251
, pp. 1366-1370
-
-
Kinzler, K.W.1
-
6
-
-
4944240144
-
Genetic predisposition to colorectal cancer
-
de la Chapelle A. (2004) Genetic predisposition to colorectal cancer. Nat. Rev. Cancer. 4:769-80.
-
(2004)
Nat. Rev. Cancer.
, vol.4
, pp. 769-780
-
-
de la Chapelle, A.1
-
7
-
-
0034909923
-
Polymorphisms and colorectal tumor risk
-
Houlston RS, Tomlinson IP. (2001) Polymorphisms and colorectal tumor risk. Gastroenterology. 121:282-301.
-
(2001)
Gastroenterology
, vol.121
, pp. 282-301
-
-
Houlston, R.S.1
Tomlinson, I.P.2
-
8
-
-
0033799531
-
Modifier genes convert "simple" Mendelian disorders to complex traits
-
Dipple KM, McCabe ER. (2000) Modifier genes convert "simple" Mendelian disorders to complex traits. Mol. Genet. Metab. 71:43-50.
-
(2000)
Mol. Genet. Metab.
, vol.71
, pp. 43-50
-
-
Dipple, K.M.1
McCabe, E.R.2
-
9
-
-
0035173781
-
Explaining differences in the severity of familial adenomatous polyposis and the search for modifier genes
-
Houlston R, Crabtree M, Phillips R, Tomlinson I. (2001) Explaining differences in the severity of familial adenomatous polyposis and the search for modifier genes. Gut. 48:1-5.
-
(2001)
Gut
, vol.48
, pp. 1-5
-
-
Houlston, R.1
Crabtree, M.2
Phillips, R.3
Tomlinson, I.4
-
10
-
-
0023886544
-
Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II)
-
Lynch HT, et al. (1988) Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II). Dis. Colon Rectum. 31:439-44.
-
(1988)
Dis. Colon Rectum.
, vol.31
, pp. 439-444
-
-
Lynch, H.T.1
-
11
-
-
0035162347
-
Hereditary nonpolyposis colorectal cancer in 95 families: Differences and similarities between mutation-positive and mutationnegative kindreds
-
Scott RJ, et al. (2001) Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutationnegative kindreds. Am. J. Hum. Genet. 68:118-27.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 118-127
-
-
Scott, R.J.1
-
12
-
-
33751078059
-
GSTM1 and GSTT1 polymorphisms as modifiers of age at diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) in a homogeneous cohort of individuals carrying a single predisposing mutation
-
Felix R, et al. (2006) GSTM1 and GSTT1 polymorphisms as modifiers of age at diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) in a homogeneous cohort of individuals carrying a single predisposing mutation. Mutat. Res. 602:175-81.
-
(2006)
Mutat. Res.
, vol.602
, pp. 175-181
-
-
Felix, R.1
-
13
-
-
0033168092
-
N-acetyltransferase 2 influences cancer prevalence in hMLH1/hMSH2 mutation carriers
-
Heinimann K, et al. (1999) N-acetyltransferase 2 influences cancer prevalence in hMLH1/hMSH2 mutation carriers. Cancer Res. 59:3038-40.
-
(1999)
Cancer Res
, vol.59
, pp. 3038-3040
-
-
Heinimann, K.1
-
14
-
-
33144460815
-
Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status
-
Menin C, et al. (2006) Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status. J. Natl. Cancer Inst. 98:285-8.
-
(2006)
J. Natl. Cancer Inst.
, vol.98
, pp. 285-288
-
-
Menin, C.1
-
15
-
-
39649101283
-
Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer
-
Talseth BA, et al. (2008) Aurora-A and Cyclin D1 polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer. Int. J. Cancer. 122:1273-7.
-
(2008)
Int. J. Cancer.
, vol.122
, pp. 1273-1277
-
-
Talseth, B.A.1
-
16
-
-
33845326134
-
Genetic polymorphisms in xenobiotic clearance genes and their influence on disease expression in hereditary nonpolyposis colorectal cancer patients
-
Talseth BA, et al. (2006) Genetic polymorphisms in xenobiotic clearance genes and their influence on disease expression in hereditary nonpolyposis colorectal cancer patients. Cancer Epidemiol. Biomarkers Prev. 15:2307-10.
-
(2006)
Cancer Epidemiol. Biomarkers Prev.
, vol.15
, pp. 2307-2310
-
-
Talseth, B.A.1
-
17
-
-
31544479522
-
IGF1 gene polymorphism and risk for hereditary nonpolyposis colorectal cancer
-
Zecevic M, et al. (2006) IGF1 gene polymorphism and risk for hereditary nonpolyposis colorectal cancer. J. Natl. Cancer Inst. 98:139-43.
-
(2006)
J. Natl. Cancer Inst.
, vol.98
, pp. 139-143
-
-
Zecevic, M.1
-
18
-
-
14844354250
-
Accumulation of miR-155 and BIC RNA in human B cell lymphomas
-
Eis PS, et al. (2005) Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc. Natl. Acad. Sci. U. S. A. 102:3627-32.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 3627-3632
-
-
Eis, P.S.1
-
19
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature. 435:834-8.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
-
20
-
-
0142120587
-
Reduced accumulation of specific microRNAs in colorectal neoplasia
-
Michael MZ, O'Connor SM, van Holst Pellekaan NG, Young GP, James RJ. (2003) Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol. Cancer Res. 1:882-91.
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 882-891
-
-
Michael, M.Z.1
O'Connor, S.M.2
van Holst Pellekaan, N.G.3
Young, G.P.4
James, R.J.5
-
21
-
-
33751520430
-
Natural selection on human microRNA binding sites inferred from SNP data
-
Chen K, Rajewsky N. (2006) Natural selection on human microRNA binding sites inferred from SNP data. Nat. Genet. 38:1452-6.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1452-1456
-
-
Chen, K.1
Rajewsky, N.2
-
22
-
-
0036290051
-
A novel gene IC53 stimulates ECV304 cell proliferation and is upregulated in failing heart
-
Chen J, Liu B, Liu Y, et al. (2002) A novel gene IC53 stimulates ECV304 cell proliferation and is upregulated in failing heart. Biochem. Biophys. Res. Commun. 294:161-6.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.294
, pp. 161-166
-
-
Chen, J.1
Liu, B.2
Liu, Y.3
-
23
-
-
34447301769
-
Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma
-
Stav D, Bar I, Sandbank J. (2007) Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma. Int. J. Biol. Markers. 22:108-13.
-
(2007)
Int. J. Biol. Markers.
, vol.22
, pp. 108-113
-
-
Stav, D.1
Bar, I.2
Sandbank, J.3
-
24
-
-
20144383299
-
Cdk5 activatorbinding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint
-
Jiang H, Luo S, Li H. (2005) Cdk5 activatorbinding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint. J. Biol. Chem. 280:20651-9.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20651-20659
-
-
Jiang, H.1
Luo, S.2
Li, H.3
-
25
-
-
34548236254
-
LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB
-
Wang J, An H, Mayo MW, Baldwin AS, Yarbrough WG. (2007) LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB. Cancer Cell. 12:239-51.
-
(2007)
Cancer Cell
, vol.12
, pp. 239-251
-
-
Wang, J.1
An, H.2
Mayo, M.W.3
Baldwin, A.S.4
Yarbrough, W.G.5
-
26
-
-
30744456521
-
A novel ARF-binding protein (LZAP) alters ARF regulation of HDM2
-
Wang J, He X, Luo Y, Yarbrough WG. (2006) A novel ARF-binding protein (LZAP) alters ARF regulation of HDM2. Biochem. J. 393:489-501.
-
(2006)
Biochem. J.
, vol.393
, pp. 489-501
-
-
Wang, J.1
He, X.2
Luo, Y.3
Yarbrough, W.G.4
-
27
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G, Milstein C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 256:495-7.
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
28
-
-
14444288522
-
The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
-
Huang HS, et al. (1997) The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J Biol. Chem. 272:2927-35.
-
(1997)
J Biol. Chem.
, vol.272
, pp. 2927-2935
-
-
Huang, H.S.1
-
29
-
-
0036117920
-
Integrins in invasive growth
-
Brakebusch C, Bouvard D, Stanchi F, Sakai T, Fassler R. (2002) Integrins in invasive growth. J. Clin. Invest. 109:999-1006.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 999-1006
-
-
Brakebusch, C.1
Bouvard, D.2
Stanchi, F.3
Sakai, T.4
Fassler, R.5
-
30
-
-
0034201965
-
Alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway
-
Lee JW, Juliano RL. (2000) Alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway. Mol. Biol. Cell. 11:1973-87.
-
(2000)
Mol. Biol. Cell.
, vol.11
, pp. 1973-1987
-
-
Lee, J.W.1
Juliano, R.L.2
-
31
-
-
0034721853
-
Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells
-
Shao J, Sheng H, Inoue H, Morrow JD, DuBois RN. (2000) Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J Biol. Chem. 275:33951-6.
-
(2000)
J Biol. Chem.
, vol.275
, pp. 33951-33956
-
-
Shao, J.1
Sheng, H.2
Inoue, H.3
Morrow, J.D.4
Dubois, R.N.5
-
32
-
-
0035947586
-
Prostaglandin E2 increases growth and motility of colorectal carcinoma cells
-
Sheng H, Shao J, Washington MK, DuBois RN. (2001) Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J. Biol. Chem. 276:18075-81.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18075-18081
-
-
Sheng, H.1
Shao, J.2
Washington, M.K.3
Dubois, R.N.4
-
33
-
-
0037063999
-
Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway
-
Ghatak S, Misra S, Toole BP. (2002) Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. J. Biol. Chem. 277:38013-20.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38013-38020
-
-
Ghatak, S.1
Misra, S.2
Toole, B.P.3
-
34
-
-
0034194714
-
Matrix survival signaling: From fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase
-
Almeida EA, et al. (2000) Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase. J. Cell Biol. 149:741-54.
-
(2000)
J. Cell Biol.
, vol.149
, pp. 741-754
-
-
Almeida, E.A.1
-
35
-
-
0035907390
-
Akt participation in the Wnt signaling pathway through Dishevelled
-
Fukumoto S, et al. (2001) Akt participation in the Wnt signaling pathway through Dishevelled. J. Biol. Chem. 276:17479-83.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17479-17483
-
-
Fukumoto, S.1
-
36
-
-
0034020459
-
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
-
Holland EC, et al. (2000) Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat. Genet. 25:55-7.
-
(2000)
Nat. Genet.
, vol.25
, pp. 55-57
-
-
Holland, E.C.1
-
37
-
-
0033607633
-
Phosphorylation and regulation of Raf by Akt (protein kinase B)
-
Zimmermann S, Moelling K. (1999) Phosphorylation and regulation of Raf by Akt (protein kinase B). Science. 286:1741-4.
-
(1999)
Science
, vol.286
, pp. 1741-1744
-
-
Zimmermann, S.1
Moelling, K.2
-
38
-
-
0033964878
-
Cloning of three novel neuronal Cdk5 activator binding proteins
-
Ching YP, Qi Z, Wang JH. (2000) Cloning of three novel neuronal Cdk5 activator binding proteins. Gene. 242:285-94.
-
(2000)
Gene
, vol.242
, pp. 285-294
-
-
Ching, Y.P.1
Qi, Z.2
Wang, J.H.3
-
39
-
-
33644809309
-
CDK5 is a novel regulatory protein in PPARgamma ligand-induced antiproliferation
-
Kim E, Chen F, Wang CC, Harrison LE. (2006) CDK5 is a novel regulatory protein in PPARgamma ligand-induced antiproliferation. Int. J. Oncol. 28:191-4.
-
(2006)
Int. J. Oncol.
, vol.28
, pp. 191-194
-
-
Kim, E.1
Chen, F.2
Wang, C.C.3
Harrison, L.E.4
|