GSTM1 and GSTT1 polymorphisms as modifiers of age at diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) in a homogeneous cohort of individuals carrying a single predisposing mutation

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 602, Issue 1-2, 2006, Pages 175-181

  Felix, Rebecca ^a   Bodmer, Walter ^b   Fearnhead, Nicola S ^b   van der Merwe, Lize ^a   Goldberg, Paul ^c   Ramesar, Rajkumar S ^a  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Glutathione S transferases (GSTT1, GSTM1); Hereditary nonpolyposis colorectal cancer (HNPCC); Modifier genes

Indexed keywords

GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; PROTEIN MLH1;

ADULT; ARTICLE; CANCER RISK; CANCER SCREENING; CANCER SURVIVAL; CANCER SUSCEPTIBILITY; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE PREDISPOSITION; FAMILIAL CANCER; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; NONSENSE MUTATION; NULL ALLELE; ONSET AGE; PRIORITY JOURNAL; SCREENING TEST;

ADOLESCENT; ADULT; AGED; CHILD; COHORT STUDIES; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; MIDDLE AGED; POINT MUTATION; POLYMORPHISM, GENETIC;

EID: 33751078059     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2006.09.004     Document Type: Article

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