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Volumn 48, Issue 1, 2001, Pages 1-5

Explaining differences in the severity of familial adenomatous polyposis and the search for modifier genes

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; GENE PRODUCT;

EID: 0035173781     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.48.1.1     Document Type: Review
Times cited : (56)

References (48)
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    • Rozen, P.1    Samuel, Z.2    Shomrat, R.3
  • 21
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    • Attenuated familial adenomatous polyposis due to a mutation in the 3′ part of the APC gene. A clue for understanding the function of the APC protein
    • (1996) Hum Genet , vol.97 , pp. 579-584
    • Friedl, W.1    Meuschel, S.2    Caspari, R.3
  • 24
    • 0031980296 scopus 로고    scopus 로고
    • A family with attenuated familial adenomatous polyposis due to a mutation in the alternatively spliced region of APC exon 9
    • (1998) Hum Mutat , vol.11 , pp. 450-455
    • Young, J.1    Simms, L.2    Tarish, J.3
  • 25
    • 0030880792 scopus 로고    scopus 로고
    • Severe upper gastrointestinal polyposis associated with sparse colonic polyposis in a familial adenomatous polyposis family with an APC mutation at codon 1520
    • (1997) Gut , vol.41 , pp. 518-521
    • Leggett, B.1    Young, J.2    Biden, K.3
  • 28
    • 0033561521 scopus 로고    scopus 로고
    • Dominant negative effect of the APC1309 mutation: A possible explanation for genotype-phenotype correlations in familial adenomatous polyposis
    • (1999) Cancer Res , vol.59 , pp. 1857-1860
    • Dihlmann, S.1    Gebert, J.2    Siermann, A.3
  • 30
    • 0032823133 scopus 로고    scopus 로고
    • The type of somatic mutation at APC in FAP is determined by the site of the germline mutation: A new facet to Knudson's 'two-hit' hypothesis
    • (1999) Nat Med , vol.5 , pp. 1071-1075
    • Lamlum, H.1    Ilyas, M.2    Rowan, A.3
  • 39
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    • Secretory phospholipase A2 does not appear to be associated with phenotypic variation in familial adenomatous polyposis
    • (1996) Hum Genet , vol.98 , pp. 386-390
    • Dobbie, Z.1    Muller, H.2    Scott, R.3
  • 40
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    • Variants at the secretory phospholipase A2 (PLA2G2A) locus: Analysis of associations with familial adenomatous polyposis and sporadic colorectal tumours
    • (1996) Ann Hum Genet , vol.60 , pp. 369-376
    • Tomlinson, I.1    Beck, N.2    Neale, K.3
  • 45
  • 48
    • 6844257555 scopus 로고    scopus 로고
    • Transcript dosage effect in familial adenomatous polyposis: Model offered by two kindreds with exon 9 APC gene mutations
    • (1998) Hum Mutat , vol.11 , pp. 197-201
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.