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Volumn 6, Issue 8, 2011, Pages 1485-1494

Synthesis, Structural Characterization, and Pro-apoptotic Activity of 1-Indanone Thiosemicarbazone Platinum(II) and Palladium(II) Complexes: Potential as Antileukemic Agents

(11) Gómez, Natalia a Santos, Diego b Vázquez, Ramiro a Suescun, Leopoldo c Mombrú, Álvaro c Vermeulen, Monica e Finkielsztein, Liliana a Shayo, Carina d Moglioni, Albertina a Gambino, Dinorah b Davio, Carlos a

a UNIVERSIDAD DE BUENOS AIRES (Argentina)

b UNIVERSIDAD DE LA REPÚBLICA (Uruguay)

c UNIVERSIDAD DE LA REPÚBLICA (Uruguay)

d Universidad Nacional de Río Cuarto Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina)

e INST DE INVEST HEMATOLOGICAS (Argentina)

Author keywords

Apoptosis; Drug discovery; Leukemia; Metal complexes; Thiosemicarbazones

Indexed keywords

1 INDANONE THIOSEMICARBAZONE PALLADIUM; 1 INDANONE THIOSEMICARBAZONE PLATINUM; ANTILEUKEMIC AGENT; CASPASE 3; LACTATE DEHYDROGENASE; LIPOCORTIN 5; PALLADIUM; PLATINUM; THIOSEMICARBAZIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRAIN U937; CONTROLLED STUDY; DNA BINDING; DRUG ACTIVITY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; INHIBITION KINETICS; LIVER TOXICITY; PRIORITY JOURNAL; X RAY DIFFRACTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; HUMANS; INDANS; LEUKEMIA; MOLECULAR CONFORMATION; PALLADIUM; PLATINUM; THIOSEMICARBAZONES; U937 CELLS;

EID: 79960695772 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201100060 Document Type: Article

Times cited : (22)

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