Antitumor activity of (-)-α-bisabolol-based thiosemicarbazones against human tumor cell lines

European Journal of Medicinal Chemistry

Volumn 45, Issue 7, 2010, Pages 2987-2993

  Da Silva, Alan P ^a   Martini, Manuele V ^a   De Oliveira, Cecília M A ^b   Cunha, Silvio ^c   De Carvalho, João E ^d   Ruiz, Ana L T G ^d   Da Silva, Cleuza C ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^c FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^d Unicamp   (Brazil)

Author keywords

Bisabolol; Antitumoral activity; Thiosemicarbazones

Indexed keywords

6 METHYL 2 (4 METHYLCYCLOHEX 3 ENYL) 6 ISOTHIOCYANO HEPTAN 2 OL; BISABOLOL; DOXORUBICIN; N (1) 2 CHLORO BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 2 NITRO BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 3 CHLORO BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 3 NITRO BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 4 CHLORO BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 4 DIMETHYLAMINO BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 4 HYDROXY BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 4 METHOXY BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZON; N (1) 4 METHOXY BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 4 METHYLBENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) 4 NITRO BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) BENZALDEHYDE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) DIPHENYLKETONE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (1) METHYLPHENYL KETONE N (4-6) [2 2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZONE; N (4-6) [2 (2 HYDROXYL 6 METHYL 2 (1 4 METHYLCYCLOHEX 3 ENYL)HEPTANYL]THIOSEMICARBAZIDE; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL STRAIN K 562; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LC 50; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; SESQUITERPENES; THIOSEMICARBAZONES;

EID: 77954348843     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.03.026     Document Type: Article

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