Sodium phenylbutyrate ameliorates focal cerebral ischemic/reperfusion injury associated with comorbid type 2 diabetes by reducing endoplasmic reticulum stress and DNA fragmentation

Behavioural Brain Research

Volumn 225, Issue 1, 2011, Pages 110-116

  Srinivasan, Krishnamoorthy ^a   Sharma, Shyam S ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Caspase 12; CHOP GADD153; DNA fragmentation; ER stress; Focal cerebral ischemia; GRP78; Sodium 4 phenylbutyrate; Type 2 diabetes

Indexed keywords

4 PHENYLBUTYRIC ACID; CASPASE 12; CCAAT ENHANCER BINDING PROTEIN EPSILON; DNA; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN BLOOD FLOW; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; COMORBIDITY; CONTROLLED STUDY; CONVALESCENCE; DISEASE ASSOCIATION; DISEASE MODEL; DNA FRAGMENTATION; DRUG DOSE COMPARISON; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GLUCOSE BLOOD LEVEL; GRIP STRENGTH; MALE; NEUROPROTECTION; NICK END LABELING; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; ROTAROD TEST; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; BODY WEIGHT; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DNA FRAGMENTATION; ENDOPLASMIC RETICULUM STRESS; HAND STRENGTH; HEAT-SHOCK PROTEINS; MALE; MOTOR ACTIVITY; NERVOUS SYSTEM DISEASES; PHENYLBUTYRATES; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; REPERFUSION INJURY; TRANSCRIPTION FACTOR CHOP; TREATMENT OUTCOME;

EID: 79960664588     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.07.004     Document Type: Article

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