메뉴 건너뛰기




Volumn 63, Issue 5, 2011, Pages 763-770

Induction of apoptosis by α-Tocotrienol in human cancer cell lines and leukemic blasts from patients: Dependency on bid, cytochrome c, and caspase pathway

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOTRIENOL; CASPASE; CYTOCHROME C; DELTA TOCOTRIENOL; GAMMA TOCOTRIENOL; PROTEIN BID; TOCOPHEROL DERIVATIVE; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; BID PROTEIN, HUMAN; CHROMAN DERIVATIVE; DRUG DERIVATIVE; PLASTOCHROMANOL 8; TUMOR PROTEIN;

EID: 79960617315     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2011.563030     Document Type: Article
Times cited : (23)

References (23)
  • 1
    • 0030015296 scopus 로고    scopus 로고
    • Appelqvist L.A
    • Kamal-Eldin A: Appelqvist L.A. Lipids 31, 671-701, 1996.
    • (1996) Lipids , vol.31 , pp. 671-701
    • Kamal-Eldin, A.1
  • 2
    • 0033037413 scopus 로고    scopus 로고
    • Vitamin E: Function and metabolism
    • Brigelius-Flohe R and Traber MG: Vitamin E: function and metabolism. FASEB J 13, 1145-1155, 1999. (Pubitemid 29300361)
    • (1999) FASEB Journal , vol.13 , Issue.10 , pp. 1145-1155
    • Brigelius-Flohe, R.1    Traber, M.G.2
  • 3
    • 77951210231 scopus 로고    scopus 로고
    • Gamma- and deltatocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression
    • Pierpaoli E, Viola V, Pilolli F, Piroddi M, Galli F, et al.: Gamma- and deltatocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression. Life Sci 24, 668-675, 2010.
    • (2010) Life Sci , vol.24 , pp. 668-675
    • Pierpaoli, E.1    Viola, V.2    Pilolli, F.3    Piroddi, M.4    Galli, F.5
  • 4
    • 77958468408 scopus 로고    scopus 로고
    • Gamma-tocotrienol but not gamma-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents
    • Kannappan R, Yadav VR, and Aggarwal BB: Gamma-tocotrienol but not gamma-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents. J Biol Chem 22, 33520-33528, 2010.
    • (2010) J Biol Chem , vol.22 , pp. 33520-33528
    • Kannappan, R.1    Yadav, V.R.2    Aggarwal, B.B.3
  • 5
    • 33644891347 scopus 로고    scopus 로고
    • Tocotrienols: Vitamin e beyond tocopherols
    • Sen CK, Khanna S, and Roy S: Tocotrienols: vitamin E beyond tocopherols. Life Sci 27, 2088-2098, 2006.
    • (2006) Life Sci , vol.27 , pp. 2088-2098
    • Sen, C.K.1    Khanna, S.2    Roy, S.3
  • 6
    • 33748634627 scopus 로고    scopus 로고
    • Apoptosis induction by γ-tocotrienol in human hepatoma Hep3B cells
    • DOI 10.1016/j.jnutbio.2005.11.001, PII S0955286305002913
    • Sakai M, Okabe M, Tachibana H, and Yamada K: Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. J Nutr Biochem 17, 672-676, 2006. (Pubitemid 44380370)
    • (2006) Journal of Nutritional Biochemistry , vol.17 , Issue.10 , pp. 672-676
    • Sakai, M.1    Okabe, M.2    Tachibana, H.3    Yamada, K.4
  • 7
    • 78449309277 scopus 로고    scopus 로고
    • Gamma-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment
    • Kunnumakkara AB, Sung B, Ravindran J, Diagaradjane P, Deorukhkar A, et al.: Gamma-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment. Cancer Res 70, 8695-8705, 2010.
    • (2010) Cancer Res , vol.70 , pp. 8695-8705
    • Kunnumakkara, A.B.1    Sung, B.2    Ravindran, J.3    Diagaradjane, P.4    Deorukhkar, A.5
  • 8
    • 77955787273 scopus 로고    scopus 로고
    • AndWu JM: Gamma-tocotrienol controls proliferation, modulates expression of cell cycle regulatory proteins and upregulates quinone reductase NQO2 in MCF-7 breast cancer cells
    • Hsieh TC, Elangovan S, andWu JM: Gamma-tocotrienol controls proliferation, modulates expression of cell cycle regulatory proteins and upregulates quinone reductase NQO2 in MCF-7 breast cancer cells. Anticancer Res 30, 2869-2874, 2010.
    • (2010) Anticancer Res , vol.30 , pp. 2869-2874
    • Hsieh, T.C.1    Elangovan, S.2
  • 9
    • 74049089011 scopus 로고    scopus 로고
    • Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells
    • Yang Z, Xiao H, Jin H, Koo PT, Tsang DJ, et al.: Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. Int J Cancer 15, 852-863, 2010.
    • (2010) Int J Cancer , vol.15 , pp. 852-863
    • Yang, Z.1    Xiao, H.2    Jin, H.3    Koo, P.T.4    Tsang, D.J.5
  • 10
    • 67649399439 scopus 로고    scopus 로고
    • Evidence of gamma-tocotrienol as an apoptosis-inducing, invasion-suppressing, and chemotherapy drug-sensitizing agent in human melanoma cells
    • Chang PN, Yap WN, Lee DT, Ling MT, Wong YC, et al.: Evidence of gamma-tocotrienol as an apoptosis-inducing, invasion-suppressing, and chemotherapy drug-sensitizing agent in human melanoma cells. Nutr Cancer 61, 357-366, 2009.
    • (2009) Nutr Cancer , vol.61 , pp. 357-366
    • Chang, P.N.1    Yap, W.N.2    Lee, D.T.3    Ling, M.T.4    Wong, Y.C.5
  • 11
    • 77049086006 scopus 로고    scopus 로고
    • Inhibitory effects of gammatocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells
    • Liu HK, Wang Q, Li Y, SunWG, Liu JR, et al.: Inhibitory effects of gammatocotrienol on invasion and metastasis of human gastric adenocarcinoma SGC-7901 cells. J Nutr Biochem 21, 206-213, 2009.
    • (2009) J Nutr Biochem , vol.21 , pp. 206-213
    • Liu, H.K.1    Wang, Q.2    Li, Y.3    Sunwg Liu, J.R.4
  • 12
    • 26444439065 scopus 로고    scopus 로고
    • Tumor suppressive effects of tocotrienol in vivo and in vitro
    • DOI 10.1016/j.canlet.2005.06.036, PII S030438350500621X
    • Wada S, Satomi Y, Murakoshi M, Noguchi N, Yoshikawa T, et al.: Tumor suppressive effects of tocotrienol in vivo and in vitro. Cancer Lett 229, 181-191, 2005. (Pubitemid 41429357)
    • (2005) Cancer Letters , vol.229 , Issue.2 , pp. 181-191
    • Wada, S.1    Satomi, Y.2    Murakoshi, M.3    Noguchi, N.4    Yoshikawa, T.5    Nishino, H.6
  • 13
    • 0030950694 scopus 로고    scopus 로고
    • Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo
    • He L, MoH, Hadisusilo S, Qureshi AA, and Elson CE: Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo. J Nutr 127, 668-674, 1997. (Pubitemid 27200738)
    • (1997) Journal of Nutrition , vol.127 , Issue.5 , pp. 668-674
    • He, L.1    Mo, H.2    Hadisusilo, S.3    Qureshi, A.A.4    Elson, C.E.5
  • 14
    • 77950327415 scopus 로고    scopus 로고
    • In vivo evidence of gamma-tocotrienol as a chemosensitizer in the treatment of hormonerefractory prostate cancer
    • Yap WN, Zaiden N, Luk SY, Lee DT, Ling MT, et al.: In vivo evidence of gamma-tocotrienol as a chemosensitizer in the treatment of hormonerefractory prostate cancer. Pharmacology 85, 248-258, 2010.
    • (2010) Pharmacology , vol.85 , pp. 248-258
    • Yap, W.N.1    Zaiden, N.2    Luk, S.Y.3    Lee, D.T.4    Ling, M.T.5
  • 15
    • 0032924755 scopus 로고    scopus 로고
    • Resistance to nitric oxide-mediated apoptosis in HL-60 variant cells is associated with increased activities of Cu,Zn-superoxide dismutase and catalase
    • DOI 10.1016/S0891-5849(98)00203-2, PII S0891584998002032
    • Yabuki M, Kariya S, Ishisaka R, Yasuda T, Yoshioka T, et al.: Resistance to nitric oxide-mediated apoptosis in HL-60 variant cells is associated with increased activities of Cu, Zn-super oxide dismutase and catalase. Free Radic Biol Med 26, 325-332, 1999. (Pubitemid 29013463)
    • (1999) Free Radical Biology and Medicine , vol.26 , Issue.3-4 , pp. 325-332
    • Yabuki, M.1    Kariya, S.2    Ishisaka, R.3    Yasuda, T.4    Yoshioka, T.5    Horton, A.A.6    Utsumi, K.7
  • 16
    • 0030782177 scopus 로고    scopus 로고
    • Cytochrome c: Can't live with it - Can't live without it
    • Reed JC: Cytochrome c: cant live with it-cant live without it. Cell 91, 559-562, 1997. (Pubitemid 27513646)
    • (1997) Cell , vol.91 , Issue.5 , pp. 559-562
    • Reed, J.C.1
  • 17
    • 0033571045 scopus 로고    scopus 로고
    • The proapoptotic proteins, Bid, and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol
    • Kluck RM, Esposti MD, Perkins G, Renken C, Kuwana T, et al.: The proapoptotic proteins, Bid, and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol. J Cell Biol 147, 809-822, 1999.
    • (1999) J Cell Biol , vol.147 , pp. 809-822
    • Kluck, R.M.1    Esposti, M.D.2    Perkins, G.3    Renken, C.4    Kuwana, T.5
  • 18
    • 3042551365 scopus 로고    scopus 로고
    • Proapoptotic mechanisms of action of a novel vitamin e analog (alpha-TEA) and a naturally occurring from vitamin e (delta-tocotrienol) in MDA-MB-435 human breast cancer cells
    • Shun MC, Yu W, Gpor A, Parsons R, Parsons, AJ, et al.: Proapoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring from vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells. Nutr Cancer 48, 205-211, 2004.
    • (2004) Nutr Cancer , vol.48 , pp. 205-211
    • Shun, M.C.1    Yu, W.2    Gpor, A.3    Parsons, R.4    Parsons, A.J.5
  • 19
    • 3843146442 scopus 로고    scopus 로고
    • Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association
    • Agarwal MK, Agarwal ML, Agarwal AM, and Gupta S: Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association. Cell Cycle 3, 205-211, 2004. (Pubitemid 40268698)
    • (2004) Cell Cycle , vol.3 , Issue.2 , pp. 205-211
    • Agarwal, M.K.1    Agarwal, M.L.2    Athar, M.3    Gupta, S.4
  • 20
    • 0042512196 scopus 로고    scopus 로고
    • Role of caspase-8 activation in mediating vitamin E-induced apoptosis in murine mammary cancer cells
    • Shah S, Gaspor A, and Sylvester PW: Role of caspase-8 activation in mediating vitamine E-induced apoptosis in murine mammary cancer cells. Nutr Cancer 45, 236-246, 2003. (Pubitemid 37022798)
    • (2003) Nutrition and Cancer , vol.45 , Issue.2 , pp. 236-246
    • Shah, S.1    Gapor, A.2    Sylvester, P.W.3
  • 21
    • 1642579535 scopus 로고    scopus 로고
    • Disruption of mitochondria during tocotrienol-induced apoptosis in MDA-MB-231 human breast cancer cells
    • DOI 10.1016/j.bcp.2003.07.015
    • Takahashi K and Loo G: Disruption of mitochondria during tocotrienolinduced apoptosis in MDA-MB231 human breast cancer cells. Biochem Pharmacol 67, 315-324, 2004. (Pubitemid 38112762)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.2 , pp. 315-324
    • Takahashi, K.1    Loo, G.2
  • 22
    • 45549083517 scopus 로고    scopus 로고
    • Β-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling
    • SunW, Wang Q, Chen B, Liu J, Liu H, et al.: Β-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling. Br J Nutr 99, 1247-1254, 2008.
    • (2008) Br J Nutr , vol.99 , pp. 1247-1254
    • Sunw Wang, Q.1    Chen, B.2    Liu, J.3    Liu, H.4
  • 23
    • 4644265799 scopus 로고    scopus 로고
    • Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: Dependency on reactive oxygen species, Akt, Bid, cytochrome c, and caspase pathway
    • DOI 10.1016/j.freeradbiomed.2004.07.003, PII S0891584904005428
    • Inoue A, Muranaka S, Fujita H, Kanno T, Tamai H, et al.: Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: dependency on reactive oxygen species, Akt, Bid, cytochrome c and caspase pathway. Free Radic Biol Med 37, 1290-1299, 2004. (Pubitemid 39302541)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.8 , pp. 1290-1299
    • Inoue, A.1    Muranaka, S.2    Fujita, H.3    Kanno, T.4    Tamai, H.5    Utsumi, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.