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Volumn 30, Issue 7, 2010, Pages 2869-2874

γ-tocotrienol controls proliferation, modulates expression of cell cycle regulatory proteins and up-regulates quinone reductase NQO2 in MCF-7 breast cancer cells

Author keywords

tocotrienol; Breast cancer; Cell cycle; Cyclin D1; MCF 7 cells; Quinone reductase NQO2; Retinoblastoma

Indexed keywords

CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 4; ESTROGEN RECEPTOR; GAMMA TOCOTRIENOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE) 2; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG;

EID: 77955787273     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (24)

References (17)
  • 2
    • 0036846230 scopus 로고    scopus 로고
    • Can lifestyle modification increase survival in women diagnosed with breast cancer?
    • Rock CL and Demark-Wahnefried W: Can lifestyle modification increase survival in women diagnosed with breast cancer? J Nutr 132: 3504S-3507S, 2002.
    • (2002) J Nutr , vol.132
    • Rock, C.L.1    Demark-Wahnefried, W.2
  • 3
    • 0242442493 scopus 로고    scopus 로고
    • Nutritional Approaches to Late Toxicities of Adjuvant Chemotherapy in Breast Cancer Survivors
    • Rock E and DeMichele A: Nutritional approaches to late toxicities of adjuvant chemotherapy in breast cancer survivors. J Nutr 133: 3785S-3793S, 2003. (Pubitemid 37392601)
    • (2003) Journal of Nutrition , vol.133 , Issue.11 SUPPL. 1
    • Rock, E.1    DeMichele, A.2
  • 5
    • 0034034058 scopus 로고    scopus 로고
    • Antiproliferative and apoptotic effects of tocopherols and tocotrienols on normal mouse mammary epithelial cells
    • McIntyre BS, Briski KP, Tirmenstein MA, Fariss MW, Gapor A and Sylvester PW: Antiproliferative and apoptotic effects of tocopherols and tocotrienols on normal mouse mammary epithelial cells. Lipids 35: 171-180, 2000. (Pubitemid 30183648)
    • (2000) Lipids , vol.35 , Issue.2 , pp. 171-180
    • McIntyre, B.S.1    Briski, K.P.2    Tirmenstein, M.A.3    Fariss, M.W.4    Gapor, A.5    Sylvester, P.W.6
  • 6
    • 0034799471 scopus 로고    scopus 로고
    • RRR-alpha-tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation
    • You H, Yu W, Sanders BG and Kline K: RRR-alpha-tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation. Cell Growth Differ 12: 471-480, 2001. (Pubitemid 32906092)
    • (2001) Cell Growth and Differentiation , vol.12 , Issue.9 , pp. 471-480
    • You, H.1    Yu, W.2    Sanders, B.G.3    Kline, K.4
  • 7
    • 51349168072 scopus 로고    scopus 로고
    • Multitargeted therapy of cancer by tocotrienols
    • Nesaretnam K: Multitargeted therapy of cancer by tocotrienols. Cancer Lett 269: 388-395, 2008.
    • (2008) Cancer Lett , vol.269 , pp. 388-395
    • Nesaretnam, K.1
  • 8
    • 0030897729 scopus 로고    scopus 로고
    • Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination
    • Guthrie N, Gapor A, Chambers AF and Carroll KK: Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination. J Nutr 127: 544S-548S, 1997. (Pubitemid 27120013)
    • (1997) Journal of Nutrition , vol.127 , Issue.3
    • Guthrie, N.1    Gapor, A.2    Chambers, A.F.3    Carroll, K.K.4
  • 9
    • 33644891347 scopus 로고    scopus 로고
    • Tocotrienols: Vitamin E beyond tocopherols
    • Sen CK, Khanna S and Roy S: Tocotrienols: Vitamin E beyond tocopherols. Life Sci 78: 2088-2098, 2006.
    • (2006) Life Sci , vol.78 , pp. 2088-2098
    • Sen, C.K.1    Khanna, S.2    Roy, S.3
  • 10
    • 0031744718 scopus 로고    scopus 로고
    • Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status
    • DOI 10.1007/s11745-998-0229-3
    • Nesaretnam K, Stephen R, Dils R and Darbre P: Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status. Lipids 33: 461-469, 1998. (Pubitemid 28261949)
    • (1998) Lipids , vol.33 , Issue.5 , pp. 461-469
    • Nesaretnam, K.1    Stephen, R.2    Dils, R.3    Darbre, P.4
  • 11
    • 0033043778 scopus 로고    scopus 로고
    • Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols
    • Yu W, Simmons-Menchaca M, Gapor A, Sanders BG and Kline K: Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. Nutr Cancer 33: 26-32, 1999. (Pubitemid 29196119)
    • (1999) Nutrition and Cancer , vol.33 , Issue.1 , pp. 26-32
    • Yu, W.1    Simmons-Menchaca, M.2    Gapor, A.3    Sanders, B.G.4    Kline, K.5
  • 12
    • 3042551365 scopus 로고    scopus 로고
    • Pro-apoptotic mechanisms of action of a novel vitamin e analog (alpha-TEA) and a naturally occurring form of vitamin e (delta-Tocotrienol) in MDA-MB-435 human breast cancer cells
    • Shun MC, Yu W, Gapor A, Parsons R, Atkinson J, Sanders BG and Kline K: Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells. Nutr Cancer 48: 95-105, 2004. (Pubitemid 38823551)
    • (2004) Nutrition and Cancer , vol.48 , Issue.1 , pp. 95-105
    • Shun, M.-C.1    Yu, W.2    Gapor, A.3    Parsons, R.4    Atkinson, J.5    Sanders, B.G.6    Kline, K.7
  • 14
    • 58049109067 scopus 로고    scopus 로고
    • Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones
    • Gaikwad NW, Yang L, Rogan EG and Cavalieri EL: Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones. Free Radic Biol Med 46: 253-262, 2009.
    • (2009) Free Radic Biol Med , vol.46 , pp. 253-262
    • Gaikwad, N.W.1    Yang, L.2    Rogan, E.G.3    Cavalieri, E.L.4
  • 15
    • 25844511169 scopus 로고    scopus 로고
    • Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the Chinese herb Rabdosia rubescens
    • Hsieh TC, Wijeratne EK, Liang JY, Gunatilaka AL and Wu JM: Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the Chinese herb Rabdosia rubescens. Biochem Biophys Res Commun 337: 224-231, 2005.
    • (2005) Biochem Biophys Res Commun , vol.337 , pp. 224-231
    • Hsieh, T.C.1    Wijeratne, E.K.2    Liang, J.Y.3    Gunatilaka, A.L.4    Wu, J.M.5
  • 16
    • 67249150968 scopus 로고    scopus 로고
    • Functional polymorphisms, altered gene expression and genetic association link NRH:Quinone oxidoreductase 2 to breast cancer with wild-type p53
    • Yu KD, Di GH, Yuan WT, Fan L, Wu J, Hu Z, Shen ZZ, Zheng Y, Huang W and Shao ZM: Functional polymorphisms, altered gene expression and genetic association link NRH:quinone oxidoreductase 2 to breast cancer with wild-type p53. Hum Mol Genet 18: 2502-2517, 2009.
    • (2009) Hum Mol Genet , vol.18 , pp. 2502-2517
    • Yu, K.D.1    Di, G.H.2    Yuan, W.T.3    Fan, L.4    Wu, J.5    Hu, Z.6    Shen, Z.Z.7    Zheng, Y.8    Huang, W.9    Shao, Z.M.10
  • 17
    • 55749115443 scopus 로고    scopus 로고
    • Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product
    • Elangovan S, Hsieh TC and Wu JM: Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product. Anticancer Res 28: 2641-2647, 2008.
    • (2008) Anticancer Res , vol.28 , pp. 2641-2647
    • Elangovan, S.1    Hsieh, T.C.2    Wu, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.