Role of caspase-8 activation in mediating vitamin E-induced apoptosis in murine mammary cancer cells

Nutrition and Cancer

Volumn 45, Issue 2, 2003, Pages 236-246

  Shah, Sumit ^a   Gapor, Abdul ^b   Sylvester, Paul W ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

^b MALAYSIAN PALM OIL BOARD   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOTRIENOL; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; DNA FRAGMENT; GAMMA TOCOTRIENOL; PALM OIL; TOCOPHEROL;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CELL ACTIVITY; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; MOUSE; NICK END LABELING; NONHUMAN; SIGNAL TRANSDUCTION; STAINING;

ANIMALIA; MURINAE;

EID: 0042512196     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/S15327914NC4502_14     Document Type: Article

References (46)

1. Packer L: Protective role of vitamin E in biological systems. Am J Clin Nutr 53, 1050S-1055S, 1991.
2. Brigelius-Flohe R and Traber MG: Vitamin E: function and metabolism. FASEB J 13, 1145-1155, 1999.
3. Kimmick GG, Bell RA, and Bostick RM: Vitamin E and breast cancer: a review. Nutr Cancer 27, 109-117, 1997.
4. Cottrell RC: Introduction: nutritional aspects of palm oil. Am J Clin Nutr 53, 989S-1009S, 1991.
5. Elson CE: Tropical oils: nutritional and scientific issues. Crit Rev Food Sci Nutr 31, 79-102, 1992.
6. Sylvester PW, Russell M, Ip MM, and Ip C: Comparative effects of different animal and vegetable fats fed before and during carcinogen administration on mammary tumorigenesis, sexual maturation, and endocrine function in rats. Cancer Res 46, 757-762, 1986.
7. McIntyre BS, Briski KP, Gapor A, and Sylvester PW: Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells. Proc Soc Exp Biol Med 224, 292-301, 2000.
8. McIntyre BS, Briski KP, Tirmenstein MA, Fariss MW, Gapor A, et al.: Antiproliferative and apoptotic effects of tocopherols and tocotrienols on normal mouse mammary epithelial cells. Lipids 35, 171-180, 2000.
9. Sylvester PW, McIntyre BS, Gapor A, and Briski KP: Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C (alpha) activation. Cell Prolif 34, 347-357, 2001.
10. Yu W, Simmons-Menchaca M, Gapor A, Sanders BG, and Kline K: Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. Nutr Cancer 33, 26-32, 1999.
11. Kumar R, Vadlamudi RK, and Adam L: Apoptosis in mammary gland and cancer. Endocr Relat Cancer 7, 257-269, 2000.
12. Kerr JF, Wyllie AH, and Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26, 239-257, 1972.
13. Earnshaw WC, Martins LM, and Kaufmann SH: Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 68, 383-424, 1999.
14. Slee EA, Adrain C, and Martin SJ: Serial killers: ordering caspase activation events in apoptosis. Cell Death Differ 6, 1067-1074, 1999.
15. Bratton SB, MacFarlane M, Cain K, and Cohen GM: Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis. Exp Cell Res 256, 27-33, 2000.
16. Sun XM, MacFarlane M, Zhuang J, Wolf BB, Green DR, et al.: Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem 274, 5053-5060, 1999.
17. Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S, and Peter ME: Apoptosis signaling by death receptors. Eur J Biochem 254, 439-459, 1998.
18. Walczak H and Krammer PH: The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 256, 58-66, 2000.
19. Green DR and Reed JC: Mitochondria and apoptosis. Science 281, 1309-1312, 1998.
20. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, et al.: Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489, 1997.
21. Antonsson B and Martinou JC: The Bcl-2 protein family. Exp Cell Res 256, 50-57, 2000.
22. Desagher S, Osen-Sand A, Nichols A, Eskes R, Montessuit S, et al.: Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J Cell Biol 144, 891-901, 1999.
23. Li H, Zhu H, Xu CJ, and Yuan J: Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94, 491-501, 1998.
24. Chen Q, Gong B, and Almasan A: Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop Iinking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis. Cell Death Differ 7, 227-233, 2000.
25. Kirsch DG, Doseff A, Chau BN, Lim DS, de Souza-Pinto NC, et al.: Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. J Biol Chem 274, 21155-21161, 1999.
26. Kline K, Yu W, and Sanders BG: Vitamin E: mechanisms of action as tumor cell growth inhibitors. J Nutr 131, 161S-163S, 2001.
27. Yu W, Liao QY, Hantash FM, Sanders BG, and Kline K: Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells. Cancer Res 61, 6569-6576, 2001.
28. Yamamoto S, Tamai H, Ishisaka R, Kanno T, Arita K, et al.: Mechanism of alpha-tocopheryl succinate-induced apoptosis of promyelocytic leukemia cells. Free Radic Res 33, 407-418, 2000.
29. Yu W, Israel K, Liao QY, Aldaz CM, Sanders BG, et al.: Vitamin E succinate (VES) induces Fas sensitivity in human breast cancer cells: role for Mr 43,000 Fas in VES-triggered apoptosis. Cancer Res 59, 953-961, 1999.
30. Neuzil J, Svensson I, Weber T, Weber C, and Brunk UT: alpha-tocopheryl succinate-induced apoptosis in Jurkat T cells involves caspase-3 activation, and both lysosomal and mitochondrial destabilisation. FEBS Lett 445, 295-300, 1999.
31. Turley JM, Ruscetti FW, Kim SJ, Fu T, Gou FV, et al.: Vitamin E succinate inhibits proliferation of BT-20 human breast cancer cells: increased binding of cyclin A negatively regulates E2F transactivation activity. Cancer Res 57, 2668-2675, 1997.
32. Yu W, Heim K, Qian M, Simmons-Menchaca M, Sanders BG, et al.: Evidence for role of transforming growth factor-beta in RRR-alpha-tocopheryl succinate-induced apoptosis of human MDA-MB-435 breast cancer cells. Nutr Cancer 27, 267-278, 1997.
33. Anderson LW, Danielson KG, and Hosick HL: Metastatic potential of hyperplastic alveolar nodule derived mouse mammary tumor cells following intravenous inoculation. Eur J Cancer Clin Oncol 17, 1001-1008, 1981.
34. Danielson KG, Anderson LW, and Hosick HL: Selection and characterization in culture of mammary tumor cells with distinctive growth properties in vivo. Cancer Res 40, 1812-1819, 1980.
35. McIntyre BS, Birkenfeld HP, and Sylvester PW: Relationship between epidermal growth factor receptor levels, autophosphorylation and mitogenic-responsiveness in normal mouse mammary epithelial cells in vitro. Cell Prolif 28, 45-56, 1995.
36. Sylvester PW, Birkenfeld HP, Hosick HL, and Briski KP: Fatty acid modulation of epidermal growth factor-induced mouse mammary epithelial cell proliferation in vitro. Exp Cell Res 214, 145-153, 1994.
37. Towbin H, Staehelin T, and Gordon J: Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76, 4350-4354, 1979.
38. Sigounas G, Anagnostou A, and Steiner M: dl-alpha-Tocopherol induces apoptosis in erythroleukemia, prostate, and breast cancer cells. Nutr Cancer 28, 30-35, 1997.
39. Schwartz J and Shklar G: The selective cytotoxic effect of carotenoids and alpha-tocopherol on human cancer cell lines in vitro. J Oral Maxillofac Surg 50, 367-373, 1992.
40. Martin DA, Siegel RM, Zheng L, and Lenardo MJ: Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal. J Biol Chem 273, 4345-4349, 1998.
41. Talanian RV, Quinlan C, Trautz, S, Hackett, MC, Mankovich, JA, et al.: Substrate specificities of caspase family proteases. J Biol Chem 272, 9677-9682, 1997.
42. Shen K and Novak RF: Fas-signaling and effects on receptor tyrosine kinase signal transduction in human breast epithelial cells. Biochem Biophys Res Commun 230, 89-93, 1997.
43. Keane MM, Ettenberg SA, Lowrey GA, Russell EK, and Lipkowitz S: Fas expression and function in normal and malignant breast cell lines. Cancer Res 56, 4791-4798, 1996.
44. Thornberry NA and Lazebnik Y: Caspases: enemies within. Science 281, 1312-1316, 1998.
45. Murphy KM, Streips UN, and Lock RB: Bax membrane insertion during Fas (CD95)-induced apoptosis precedes cytochrome c release and is inhibited by Bcl-2. Oncogene 18, 5991-5999, 1999.
46. Tang D, Lahti JM, and Kidd VJ: Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis. J Biol Chem 275, 9303-9307, 2000.