A profile of NSAID-targeted arachidonic acid metabolisms in human embryonic stem cells (hESCs): Implication of the negative effects of NSAIDs on heart tissue regeneration

International Journal of Cardiology

Volumn 150, Issue 3, 2011, Pages 253-259

  Chillar, Annirudha ^a   So, Shui Ping ^a   Ruan, Cheng Huai ^b   Shelat, Harnath ^c,d   Geng, Yong Jian ^c,d   Ruan, Ke He ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d TEXAS HEART INSTITUTE   (United States)

Author keywords

Arachidonic acid; COX 2 inhibitor; Cyclooxygenase; Human embryonic stem cells; NSAIDs; Prostacyclin

Indexed keywords

ACETYLSALICYLIC ACID; ARACHIDONIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; PROSTANOID;

ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; EMBRYONIC STEM CELL; ENZYME ACTIVITY; ENZYME METABOLISM; FIBROBLAST; HEART INFARCTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MASS SPECTROMETRY; PRIORITY JOURNAL; TISSUE REGENERATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONIC ACID; CELL DIFFERENTIATION; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; EMBRYONIC STEM CELLS; FEEDER CELLS; GROWTH INHIBITORS; HEART; HUMANS; PROSTAGLANDINS; REGENERATION;

EID: 79960558699     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2010.04.015     Document Type: Article

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