LC-MS/MS sensitivity enhancement using 2D-SCX/RPLC and its application in the assessment of pharmacokinetics of clonidine in dried blood spots

Bioanalysis

Volumn 3, Issue 14, 2011, Pages 1577-1586

  Li, Fumin ^a   McMahon, Carrie ^a   Li, Fengxia ^a   Zulkoski, John ^a  

^a Late Stage Developmental Services Covance Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM ACETATE; CLONIDINE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRIED BLOOD SPOT; FLOW RATE; HEART RATE; HEMODYNAMICS; HYDROPHILICITY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; NEWBORN SCREENING; NONHUMAN; SENSITIVITY ANALYSIS; SIGNAL NOISE RATIO; TANDEM MASS SPECTROMETRY; TELEMETRY; THIN LAYER CHROMATOGRAPHY; TOXICOKINETICS; TWO DIMENSIONAL STRONG CATION EXCHANGE REVERSED PHASE LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, LIQUID; CLONIDINE; DRIED BLOOD SPOT TESTING; HUMANS; MACACA FASCICULARIS; TANDEM MASS SPECTROMETRY;

EID: 79960490471     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.119     Document Type: Article

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