Anxiolytic-like effects of 4-O-methylhonokiol isolated from magnolia officinalis through enhancement of GABAergic transmission and chloride influx

Journal of Medicinal Food

Volumn 14, Issue 7-8, 2011, Pages 724-731

  Han, Huishan ^a   Jung, Jae Kyung ^a   Han, Sang Bae ^a   Nam, Sang Yoon ^a   Oh, Ki Wan ^a   Hong, Jin Tae ^a  

^a Chungbuk National University   (South Korea)

Author keywords

4 Omethylhonokiol IN; anxiolytic like effect; chloride influx; elevated plus maze; GABAA subunits; hole board

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 O METHYLHONOKIOL; DIAZEPAM; FLUMAZENIL; HONOKIOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CHLORIDE TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; EMBRYO; EXPERIMENTAL TEST; GABAERGIC TRANSMISSION; GENE OVEREXPRESSION; HIPPOCAMPUS; HOLE BOARD TEST; LOCOMOTION; MAGNOLIA OFFICINALIS; MAGNOLIACEAE; MALE; MAZE TEST; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; TRANQUILIZING ACTIVITY; TREATMENT DURATION;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; BIOLOGICAL TRANSPORT; BIPHENYL COMPOUNDS; BRAIN; CHLORIDES; DISEASE MODELS, ANIMAL; GAMMA-AMINOBUTYRIC ACID; HUMANS; LIGNANS; MAGNOLIA; MALE; MAZE LEARNING; MICE; MICE, INBRED ICR; MOTOR ACTIVITY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A;

MAGNOLIA OFFICINALIS; MUS;

EID: 79960469399     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2010.1111     Document Type: Article

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