Antidepressant-like effect of icariin and its possible mechanism in mice

Pharmacology Biochemistry and Behavior

Volumn 82, Issue 4, 2005, Pages 686-694

  Pan, Ying ^a   Kong, Lingdong ^a   Xia, Xing ^a   Zhang, Weiyun ^a   Xia, Zhonghao ^a   Jiang, Fuxin ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Corticotropin releasing factor; Forced swimming test; Icariin; Monoamine neurotransmitters; Monoamine oxidase; Tail suspension test

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; ANTIDEPRESSANT AGENT; CORTICOTROPIN RELEASING FACTOR; ICARIIN; NEUROTRANSMITTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; EPIMEDIUM; FORCED SWIMMING TEST; IMMOBILIZATION; MALE; MOUSE; NEUROCHEMISTRY; NEUROENDOCRINE SYSTEM; NONHUMAN; PRIORITY JOURNAL; STRESS;

ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN; FLAVONOIDS; MALE; MICE; MONOAMINE OXIDASE; NEUROTRANSMITTER AGENTS; STRESS; SWIMMING;

ANIMALIA; EPIMEDIUM; EPIMEDIUM BREVICORNUM;

EID: 31844440851     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2005.11.010     Document Type: Article

References (38)

1. M.E. Alburges, N. Narang, and J.K. Wamsley A sensitive and rapid HPLC-ECD method for the simultaneous analysis of norepinephrine, dopamine, serotonin and their primary metabolites in brain tissue Biomed Chromatogr 7 1993 306 310
2. L. Arborelius, M.J. Owens, P.M. Plotsky, and C.B. Nemeroff The role of corticotropin-releasing factor in depression and anxiety disorders J Endocrinol 160 1999 1 12
3. J.M. Aubry, G. Pozzoli, and W.W. Vale Chronic treatment with the antidepressant amitriptyline decreases CRF-R1 receptor mRNA levels in the rat amygdala Neurosci Lett 266 1999 197 200
4. N. Barden, J.M. Reul, and F. Holsboer Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system? Trends Neurosci 18 1995 6 11
5. Y. Chen, L.D. Kong, X. Xia, H.F. Kung, and L. Zhang Behavioral and biochemical studies of total furocoumarins from seeds of Psoralea corylifolia in the forced swimming test in mice J Ethnopharmacol 96 2005 451 459
6. T.J. Connor, J.P. Kelly, and B.E. Leonard Forced swim test-induced neurochemical endocrine, and immune changes in the rat Pharmacol Biochem Behav 58 1997 961 967
7. T.J. Connor, P. Kelliher, Y. Shen, A. Harkin, J.P. Kelly, and B.E. Leonard Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test Pharmacol Biochem Behav 65 2000 591 597
8. K.J. Damjanoska, L.D. Van de Kar, G.H. Kindel, Y. Zhang, D.N. D'Souza, and F. Garcia Chronic fluoxetine differentially affects 5-Hydroxytryptamine (2A) receptor signaling in frontal cortex, oxytocin- and corticotropin-releasing factor-containing neurons in rat paraventricular nucleus J Pharmacol Exp Ther 306 2003 563 571
9. N. De Pedro, M.J. Delgado, M.L. Pinillos, and M. Alonso-Bedate Alpha1-adrenergic and dopaminergic receptors are involved in the anoretic effect of corticotropin-releasing factor in goldfish Life Sci 62 1998 1801 1808
10. G. Drossopoulou, K. Antoniou, E. Kitraki, G. Papathanasiou, E. Papalexi, and C. Dalla Sex differences in behavioral, neurochemical and neuroendocrine effects induced by the forced swim test in rats Neuroscience 126 2004 849 857
11. C. Garcia-Lecumberri, and E. Ambrosio Differential effect of low doses of intracerebroventricular corticotropin-releasing factor in forced swimming test Pharmacol Biochem Behav 67 2000 519 525
12. R.J. Haier, M.S. Buchsbaum, E. DeMet, and J. Wu Biological vulnerability to depression: replication of MAO and evoked potentials as risk factors Neuropsychobiology 20 1988 62 66
13. L.G. Kirby, and I. Lucki Interaction between the forced swimming test and fluoxetine treatment on extracellular 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in the rat J Pharmacol Exp Ther 282 1997 967 976
14. M. Kuroda, Y. Mimaki, Y. Sashida, E. Umegaki, M. Yamazaki, and K. Chiba Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells Planta Med 66 2000 575 577
15. Z. Lai Clinical application of Epimedium brevicornum Journal of LiaoNing College of Traditional Chinese Medicine 3 2001 266
16. A.C. Linthorst, C. Flachskamm, S.J. Hopkins, M.E. Hoadley, M.S. Labeur, and F. Holsboer Long-term intracerebro ventricular infusion of corticotropin-releasing hormone alters neuroendo crine, neurochemical, autonomic, behavioral, and cytokine responses to a systemic inflammatory challenge J Neurosci 17 1997 4448 4460
17. A.C. Linthorst, R.G. Penalva, C. Flachskamm, F. Holsboer, and J.M. Reul Forced swim stress activates rat hippocampal serotonergic neurotransmission involving a corticotropin-releasing hormone receptor-dependent mechanism Eur J Neurosci 16 2002 2441 2452
18. J. Liu, H. Ye, and Y. Lou Determination of rat urinary metabolites of icariin in vivo and estrogenic activities of its metabolites on MCF-7 cells Pharmazie 60 2005 120 125
19. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R. Randall Protein measurement with folin phenol reagent J Biol Chem 193 1951 265 275
20. X.L. Meng, and N. Zeng The research of the effect of active principle of Epimedium on monoamine neurotransmitters in hypothalamus and other function of brain of aging male rats Zhongguo Zhong Yao Za Zhi 21 1996 683 685
21. H. Miura, M. Naoi, D. Nakahara, T. Ohta, and T. Nagatsu Effects of moclobemide on forced-swimming stress and brain monoamine levels in mice Pharmacol Biochem Behav 53 1996 469 475
22. C.B. Nemeroff, and M.J. Owens Pharmacologic differences among the SSRIs: focus on monoamine transporters and the HPA axis CNS Spectr 9 2004 23 31
23. E. O'Shea, B. Esteban, J. Camarero, A.R. Green, and M.I. Colado Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ('ecstasy') on the 5-HT and dopamine concentrations in mouse brain Neuropharmacology 40 2001 65 74
24. G.N. Pandey, R.P. Sharma, P.G. Janicak, and J.M. Davis Monoamine oxidase and cortisol response in depression and schizophrenia Psychiatry Res 44 1992 1 8
25. B. Petit-Demouliere, F. Chenu, and M. Bourin Forced swimming test in mice: a review of antidepressant activity Psychopharmacology (Berl) 177 2005 245 255
26. R.D. Porsolt, A. Bertin, and M. Jalfre Behavioural despair in mice: a primary screening test for antidepressant Arch Int Pharmacodyn Ther 229 1977 327 336
27. M.L. Price, L.G. Kirby, R.J. Valentino, and I. Lucki Evidence for corticotropin-releasing factor regulation of serotonin in the lateral septum during acute swim stress: adaptation produced by repeated swimming Psychopharmacology (Berl) 162 2002 406 414
28. A. Schurr, and A. Livne Different inhibition of mitochondrial monoamine oxidase from brain by hashish components Biochem Pharmacol 25 1976 1201 1203
29. Z.Y. Shen, Y. Chen, J.H. Huang, and Z.W. Hu The gene expression profile in hypothalamus-pituitary-adrenal-thymus (HPAT) axis from EF-treated old rats Chin J Immunol 20 2004 59 62
30. M. Smialowska, M. Bajkowska, M. Heilig, E. Obuchowicz, J. Turchan, and M. Maj Pharmacological studies on the monoaminergic influence on the synthesis and expression of neuropeptide Y and corticotropin releasing factor in rat brain amygdala Neuropeptides 35 2001 82 91
31. C. Stenfors, and S.B. Ross Evidence for involvement of 5-Hydroxytryptamine(1B) autoreceptors in the enhancement of serotonin turnover in the mouse brain following repeated treatment with fluoxetine Life Sci 71 2002 2867 2880
32. L. Steru, R. Chermat, B. Thierry, and P. Simon The tail suspension test: a new method for screening antidepressants in mice Psychopharmacology (Berl) 85 1985 367 370
33. S.C. Stout, M.J. Owens, and C.B. Nemeroff Regulation of corticotropin-releasing factor neuronal systems and hypothalamic-pituitary- adrenal axis activity by stress and chronic antidepressant treatment J Pharmacol Exp Ther 300 2002 1085 1092
34. Z.Q. Wang, and Y.J. Lou Proliferation-stimulating effects of icaritin and desmethylicaritin in MCF-7 cells Eur J Pharmacol 504 2004 147 153
35. M.Q. Wang, Z.M. Bi, P. Li, H. Ji, and F.L. Cheng Determination of epimedin C and icariin in Herba Epimedii by HPLC Zhongguo Zhong Yao Za Zhi 28 2003 1025 1027
36. H. Wu, E.J. Lien, and L.L. Lien Chemical and pharmacological investigations of Epimedium species: a survey Prog Drug Res 60 2003 1 57
37. H.Y. Ye, J. Liu, and Y.J. Lou Preparation of two derivatives from icariin and investigation of their estrogen-like effects Zhejiang Da Xue Xue Bao Yi Xue Ban 34 2005 131 136
38. Z.F. Yu, L.D. Kong, and Y. Chen Antidepressant activity of aqueous extracts of Curcuma longa J Ethnopharmacol 83 2002 161 165