-
1
-
-
40849140683
-
Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression
-
Sharp P.S., et al. Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression. Neurobiol Dis 2008, 30(1):42-55.
-
(2008)
Neurobiol Dis
, vol.30
, Issue.1
, pp. 42-55
-
-
Sharp, P.S.1
-
2
-
-
40849092480
-
Heat shock proteins, endothelin, and peripheral neuronal injury
-
Klass M.G., et al. Heat shock proteins, endothelin, and peripheral neuronal injury. Neurosci Lett 2008, 433(3):188-193.
-
(2008)
Neurosci Lett
, vol.433
, Issue.3
, pp. 188-193
-
-
Klass, M.G.1
-
3
-
-
70149124059
-
Induction of heat shock protein 70 reduces the alteration of striatal electrical activity caused by mitochondrial impairment
-
Tantucci M., et al. Induction of heat shock protein 70 reduces the alteration of striatal electrical activity caused by mitochondrial impairment. Neuroscience 2009, 163(3):735-740.
-
(2009)
Neuroscience
, vol.163
, Issue.3
, pp. 735-740
-
-
Tantucci, M.1
-
4
-
-
0035363805
-
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease
-
Sittler A., et al. Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease. Hum Mol Genet 2001, 10(12):1307-1315.
-
(2001)
Hum Mol Genet
, vol.10
, Issue.12
, pp. 1307-1315
-
-
Sittler, A.1
-
5
-
-
27744517366
-
Heat shock proteins as emerging therapeutic targets
-
Soti C., et al. Heat shock proteins as emerging therapeutic targets. Br J Pharmacol 2005, 146(6):769-780.
-
(2005)
Br J Pharmacol
, vol.146
, Issue.6
, pp. 769-780
-
-
Soti, C.1
-
6
-
-
70450216770
-
Heat shock proteins in glioblastomas
-
Yang I., Fang S., Parsa A.T. Heat shock proteins in glioblastomas. Neurosurg Clin N Am 2010, 21(1):111-123.
-
(2010)
Neurosurg Clin N Am
, vol.21
, Issue.1
, pp. 111-123
-
-
Yang, I.1
Fang, S.2
Parsa, A.T.3
-
7
-
-
21744445069
-
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications
-
Ciocca D.R., Calderwood S.K. Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones 2005, 10(2):86-103.
-
(2005)
Cell Stress Chaperones
, vol.10
, Issue.2
, pp. 86-103
-
-
Ciocca, D.R.1
Calderwood, S.K.2
-
8
-
-
77649118928
-
Recombinant Fv-Hsp70 protein mediates neuroprotection after focal cerebral ischemia in rats
-
Zhan X., et al. Recombinant Fv-Hsp70 protein mediates neuroprotection after focal cerebral ischemia in rats. Stroke 2010, 41(3):538-543.
-
(2010)
Stroke
, vol.41
, Issue.3
, pp. 538-543
-
-
Zhan, X.1
-
9
-
-
77953576838
-
Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?
-
Powers M.V., et al. Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?. Cell Cycle 2010, 9(8):1542-1550.
-
(2010)
Cell Cycle
, vol.9
, Issue.8
, pp. 1542-1550
-
-
Powers, M.V.1
-
11
-
-
33747512168
-
The distinctive role of small heat shock proteins in oncogenesis
-
Laudanski K., Wyczechowska D. The distinctive role of small heat shock proteins in oncogenesis. Arch Immunol Ther Exp (Warsz) 2006, 54(2):103-111.
-
(2006)
Arch Immunol Ther Exp (Warsz)
, vol.54
, Issue.2
, pp. 103-111
-
-
Laudanski, K.1
Wyczechowska, D.2
-
13
-
-
33644835965
-
Heat shock proteins in cancer: chaperones of tumorigenesis
-
Calderwood S.K., et al. Heat shock proteins in cancer: chaperones of tumorigenesis. Trends Biochem Sci 2006, 31(3):164-172.
-
(2006)
Trends Biochem Sci
, vol.31
, Issue.3
, pp. 164-172
-
-
Calderwood, S.K.1
-
14
-
-
7444231693
-
Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets
-
Spiess C., et al. Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets. Trends Cell Biol 2004, 14(11):598-604.
-
(2004)
Trends Cell Biol
, vol.14
, Issue.11
, pp. 598-604
-
-
Spiess, C.1
-
15
-
-
44549085390
-
Chaperonins: the hunt for the Group II mechanism
-
Bigotti M.G., Clarke A.R. Chaperonins: the hunt for the Group II mechanism. Arch Biochem Biophys 2008, 474(2):331-339.
-
(2008)
Arch Biochem Biophys
, vol.474
, Issue.2
, pp. 331-339
-
-
Bigotti, M.G.1
Clarke, A.R.2
-
16
-
-
22144490883
-
[Heat shock proteins as molecular chaperones]
-
Arrigo A.P. [Heat shock proteins as molecular chaperones]. Med Sci (Paris) 2005, 21(6-7):619-625.
-
(2005)
Med Sci (Paris)
, vol.21
, Issue.6-7
, pp. 619-625
-
-
Arrigo, A.P.1
-
17
-
-
0037315208
-
Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery
-
Pratt W.B., Toft D.O. Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery. Exp Biol Med (Maywood) 2003, 228(2):111-133.
-
(2003)
Exp Biol Med (Maywood)
, vol.228
, Issue.2
, pp. 111-133
-
-
Pratt, W.B.1
Toft, D.O.2
-
18
-
-
0142186172
-
Aging and molecular chaperones
-
Soti C., Csermely P. Aging and molecular chaperones. Exp Gerontol 2003, 38(10):1037-1040.
-
(2003)
Exp Gerontol
, vol.38
, Issue.10
, pp. 1037-1040
-
-
Soti, C.1
Csermely, P.2
-
19
-
-
0033575998
-
Hot-tub therapy for type 2 diabetes mellitus
-
Hooper P.L. Hot-tub therapy for type 2 diabetes mellitus. N Engl J Med 1999, 341(12):924-925.
-
(1999)
N Engl J Med
, vol.341
, Issue.12
, pp. 924-925
-
-
Hooper, P.L.1
-
20
-
-
77950189338
-
Heat shock proteins, cell survival and drug resistance: the mitochondrial chaperone TRAP1, a potential novel target for ovarian cancer therapy
-
Landriscina M., et al. Heat shock proteins, cell survival and drug resistance: the mitochondrial chaperone TRAP1, a potential novel target for ovarian cancer therapy. Gynecol Oncol 2010, 117(2):177-182.
-
(2010)
Gynecol Oncol
, vol.117
, Issue.2
, pp. 177-182
-
-
Landriscina, M.1
-
21
-
-
13744256921
-
Membrane fluidization triggers membrane remodeling which affects the thermotolerance in Escherichia coli
-
Shigapova N., et al. Membrane fluidization triggers membrane remodeling which affects the thermotolerance in Escherichia coli. Biochem Biophys Res Commun 2005, 328(4):1216-1223.
-
(2005)
Biochem Biophys Res Commun
, vol.328
, Issue.4
, pp. 1216-1223
-
-
Shigapova, N.1
-
22
-
-
0037293568
-
Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning
-
Ferdinandy P., Schulz R. Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning. Br J Pharmacol 2003, 138(4):532-543.
-
(2003)
Br J Pharmacol
, vol.138
, Issue.4
, pp. 532-543
-
-
Ferdinandy, P.1
Schulz, R.2
-
23
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100(1):57-70.
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
24
-
-
77955088992
-
Multi-chaperone-peptide-rich mixture from colo-carcinoma cells elicits potent anticancer immunity
-
Huang C., et al. Multi-chaperone-peptide-rich mixture from colo-carcinoma cells elicits potent anticancer immunity. Cancer Epidemiol 2010.
-
(2010)
Cancer Epidemiol
-
-
Huang, C.1
-
25
-
-
77149141379
-
Hsp90 as a therapeutic target in patients with oesophageal carcinoma
-
Ekman S., et al. Hsp90 as a therapeutic target in patients with oesophageal carcinoma. Expert Opin Ther Targets 2010, 14(3):317-328.
-
(2010)
Expert Opin Ther Targets
, vol.14
, Issue.3
, pp. 317-328
-
-
Ekman, S.1
-
26
-
-
77950615028
-
Mitochondrial Hsp90 chaperones as novel molecular targets in prostate cancer
-
Altieri D.C. Mitochondrial Hsp90 chaperones as novel molecular targets in prostate cancer. Future Oncol 2010, 6(4):487-489.
-
(2010)
Future Oncol
, vol.6
, Issue.4
, pp. 487-489
-
-
Altieri, D.C.1
-
27
-
-
77649147755
-
Heat shock cognate protein 70 is essential for Akt signaling in endothelial function
-
Shiota M., et al. Heat shock cognate protein 70 is essential for Akt signaling in endothelial function. Arterioscler Thromb Vasc Biol 2010, 30(3):491-497.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, Issue.3
, pp. 491-497
-
-
Shiota, M.1
-
28
-
-
65549085219
-
Heat shock protein inhibitors and vaccines as new agents in cancer treatment
-
Karapanagiotou E.M., Syrigos K., Saif M.W. Heat shock protein inhibitors and vaccines as new agents in cancer treatment. Expert Opin Investig Drugs 2009, 18(2):161-174.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, Issue.2
, pp. 161-174
-
-
Karapanagiotou, E.M.1
Syrigos, K.2
Saif, M.W.3
-
29
-
-
34548189523
-
Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis
-
Tsutsumi S., Neckers L. Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis. Cancer Sci 2007, 98(10):1536-1539.
-
(2007)
Cancer Sci
, vol.98
, Issue.10
, pp. 1536-1539
-
-
Tsutsumi, S.1
Neckers, L.2
-
30
-
-
4744371115
-
The heat-shock protein receptors: some answers and more questions
-
Binder R.J., Vatner R., Srivastava P. The heat-shock protein receptors: some answers and more questions. Tissue Antigens 2004, 64(4):442-451.
-
(2004)
Tissue Antigens
, vol.64
, Issue.4
, pp. 442-451
-
-
Binder, R.J.1
Vatner, R.2
Srivastava, P.3
-
31
-
-
2942716692
-
Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness
-
Eustace B.K., et al. Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness. Nat Cell Biol 2004, 6(6):507-514.
-
(2004)
Nat Cell Biol
, vol.6
, Issue.6
, pp. 507-514
-
-
Eustace, B.K.1
-
32
-
-
42049084486
-
A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion
-
Tsutsumi S., et al. A small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion. Oncogene 2008, 27(17):2478-2487.
-
(2008)
Oncogene
, vol.27
, Issue.17
, pp. 2478-2487
-
-
Tsutsumi, S.1
-
33
-
-
0141484615
-
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
-
Kamal A., et al. A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 2003, 425(6956):407-410.
-
(2003)
Nature
, vol.425
, Issue.6956
, pp. 407-410
-
-
Kamal, A.1
-
34
-
-
0038069088
-
Geldanamycin and its 17-allylamino-17-demethoxy analogue antagonize the action of cisplatin in human colon adenocarcinoma cells: differential caspase activation as a basis for interaction
-
Vasilevskaya I.A., Rakitina T.V., O'Dwyer P.J. Geldanamycin and its 17-allylamino-17-demethoxy analogue antagonize the action of cisplatin in human colon adenocarcinoma cells: differential caspase activation as a basis for interaction. Cancer Res 2003, 63(12):3241-3246.
-
(2003)
Cancer Res
, vol.63
, Issue.12
, pp. 3241-3246
-
-
Vasilevskaya, I.A.1
Rakitina, T.V.2
O'Dwyer, P.J.3
-
35
-
-
20244367890
-
Bimoclomol: a non-toxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects
-
Vigh L., et al. Bimoclomol: a non-toxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects. Nat Med 1997, 3(10):1150-1154.
-
(1997)
Nat Med
, vol.3
, Issue.10
, pp. 1150-1154
-
-
Vigh, L.1
-
36
-
-
28044469532
-
Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease
-
Katsuno M., et al. Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease. Proc Natl Acad Sci U S A 2005, 102(46):16801-16806.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.46
, pp. 16801-16806
-
-
Katsuno, M.1
-
37
-
-
33746724745
-
Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein
-
Waza M., et al. Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein. J Mol Med 2006, 84(8):635-646.
-
(2006)
J Mol Med
, vol.84
, Issue.8
, pp. 635-646
-
-
Waza, M.1
-
38
-
-
33845874433
-
Brain CHIP: removing the culprits in neurodegenerative disease
-
Dickey C.A., et al. Brain CHIP: removing the culprits in neurodegenerative disease. Trends Mol Med 2007, 13(1):32-38.
-
(2007)
Trends Mol Med
, vol.13
, Issue.1
, pp. 32-38
-
-
Dickey, C.A.1
-
39
-
-
0842342532
-
The effect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fibers of the rat following peripheral nerve injury
-
Kalmar B., et al. The effect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fibers of the rat following peripheral nerve injury. Exp Neurol 2003, 184(2):636-647.
-
(2003)
Exp Neurol
, vol.184
, Issue.2
, pp. 636-647
-
-
Kalmar, B.1
-
40
-
-
58149402446
-
Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling
-
Stetler R.A., et al. Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling. J Neurosci 2008, 28(49):13038-13055.
-
(2008)
J Neurosci
, vol.28
, Issue.49
, pp. 13038-13055
-
-
Stetler, R.A.1
-
41
-
-
33646681219
-
Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity
-
Calabrese V., et al. Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity. Antioxid Redox Signal 2006, 8(3-4):444-477.
-
(2006)
Antioxid Redox Signal
, vol.8
, Issue.3-4
, pp. 444-477
-
-
Calabrese, V.1
-
42
-
-
36849005504
-
Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis
-
Gifondorwa D.J., et al. Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis. J Neurosci 2007, 27(48):13173-13180.
-
(2007)
J Neurosci
, vol.27
, Issue.48
, pp. 13173-13180
-
-
Gifondorwa, D.J.1
-
43
-
-
1942486792
-
Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
-
Kieran D., et al. Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat Med 2004, 10(4):402-405.
-
(2004)
Nat Med
, vol.10
, Issue.4
, pp. 402-405
-
-
Kieran, D.1
-
44
-
-
4143152789
-
Radicicol activates heat shock protein expression and cardioprotection in neonatal rat cardiomyocytes
-
Griffin T.M., Valdez T.V., Mestril R. Radicicol activates heat shock protein expression and cardioprotection in neonatal rat cardiomyocytes. Am J Physiol Heart Circ Physiol 2004, 287(3):H1081-H1088.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
, Issue.3
-
-
Griffin, T.M.1
Valdez, T.V.2
Mestril, R.3
-
45
-
-
3943054801
-
Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation
-
Kupatt C., et al. Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation. Arterioscler Thromb Vasc Biol 2004, 24(8):1435-1441.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, Issue.8
, pp. 1435-1441
-
-
Kupatt, C.1
-
46
-
-
58149381759
-
Rescuing cardiac malfunction: the roles of the chaperone-like small heat shock proteins
-
Chung E., Leinwand L.A. Rescuing cardiac malfunction: the roles of the chaperone-like small heat shock proteins. Circ Res 2008, 103(12):1351-1353.
-
(2008)
Circ Res
, vol.103
, Issue.12
, pp. 1351-1353
-
-
Chung, E.1
Leinwand, L.A.2
-
47
-
-
65549134708
-
HSP 70 and atherosclerosis - protector or activator?
-
Bielecka-Dabrowa A., et al. HSP 70 and atherosclerosis - protector or activator?. Expert Opin Ther Targets 2009, 13(3):307-317.
-
(2009)
Expert Opin Ther Targets
, vol.13
, Issue.3
, pp. 307-317
-
-
Bielecka-Dabrowa, A.1
-
48
-
-
0027407468
-
Heat shock and recovery protects renal allografts from warm ischemic injury and enhances HSP72 production
-
Perdrizet G.A., et al. Heat shock and recovery protects renal allografts from warm ischemic injury and enhances HSP72 production. Transplant Proc 1993, 25(1 Pt 2):1670-1673.
-
(1993)
Transplant Proc
, vol.25
, Issue.1 PART 2
, pp. 1670-1673
-
-
Perdrizet, G.A.1
-
49
-
-
76149134396
-
Immunomodulation with heat shock protein DiaPep277 to preserve beta cell function in type 1 diabetes - an update
-
Fischer B., et al. Immunomodulation with heat shock protein DiaPep277 to preserve beta cell function in type 1 diabetes - an update. Expert Opin Biol Ther 2010, 10(2):265-272.
-
(2010)
Expert Opin Biol Ther
, vol.10
, Issue.2
, pp. 265-272
-
-
Fischer, B.1
-
50
-
-
33750364777
-
Heat shock proteins induce T cell regulation of chronic inflammation
-
Hauet-Broere F., et al. Heat shock proteins induce T cell regulation of chronic inflammation. Ann Rheum Dis 2006, 65(Suppl.3):piii65-piii68.
-
(2006)
Ann Rheum Dis
, vol.65
, Issue.SUPPL. 3
-
-
Hauet-Broere, F.1
-
51
-
-
20944432903
-
Heat shock protein 27 expression in patients with chronic liver damage
-
Federico A., et al. Heat shock protein 27 expression in patients with chronic liver damage. Immunobiology 2005, 209(10):729-735.
-
(2005)
Immunobiology
, vol.209
, Issue.10
, pp. 729-735
-
-
Federico, A.1
-
52
-
-
77955199612
-
Heat shock proteins: cellular and molecular mechanisms in the central nervous system
-
Stetler R.A., et al. Heat shock proteins: cellular and molecular mechanisms in the central nervous system. Prog Neurobiol 2010, 92(2):184-211.
-
(2010)
Prog Neurobiol
, vol.92
, Issue.2
, pp. 184-211
-
-
Stetler, R.A.1
-
53
-
-
58149168845
-
Subcellular stress response and induction of molecular chaperones and folding proteins after transient global ischemia in rats
-
Truettner J.S., et al. Subcellular stress response and induction of molecular chaperones and folding proteins after transient global ischemia in rats. Brain Res 2009, 1249:9-18.
-
(2009)
Brain Res
, vol.1249
, pp. 9-18
-
-
Truettner, J.S.1
-
54
-
-
34047274469
-
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer
-
Daugaard M., et al. Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer. Cancer Res 2007, 67(6):2559-2567.
-
(2007)
Cancer Res
, vol.67
, Issue.6
, pp. 2559-2567
-
-
Daugaard, M.1
-
55
-
-
33746364784
-
Structure and mechanism of the Hsp90 molecular chaperone machinery
-
Pearl L.H., Prodromou C. Structure and mechanism of the Hsp90 molecular chaperone machinery. Annu Rev Biochem 2006, 75:271-294.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 271-294
-
-
Pearl, L.H.1
Prodromou, C.2
|