Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Penna Coutinho, Julia ^a,b   Cortopassi, Wilian Augusto ^c   Oliveira, Aline Alves ^c   França, Tanos Celmar Costa ^c   Krettli, Antoniana Ursine ^a,b  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c MILITARY INSTITUTE OF ENGINEERING   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ATORVASTATIN; BETANIDINE; CAPECITABINE; CEFALOTIN; CEFDITOREN; CEFIXIME; CEFMENOXIME; CEFMETAZOLE; CEFOTAXIME; CEFPIRAMIDE; CEFTRIAXONE; CEFUROXIME; CHLOROQUINE; DASATINIB; DICLOXACILLIN; DROPERIDOL; ENTECAVIR; EPROSARTAN; ERGOTAMINE; ITRACONAZOLE; LACTATE DEHYDROGENASE; MOXIFLOXACIN; NOVOBIOCIN; POSACONAZOLE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RESCINNAMINE; TOPOTECAN; UNINDEXED DRUG; VALACICLOVIR; ANTIMALARIAL AGENT; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PYRROLE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; CRYSTALLOGRAPHY; DRUG CONFORMATION; DRUG EFFICACY; DRUG SAFETY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; FEMALE; HYDROGEN BOND; IN VITRO STUDY; IN VIVO STUDY; MALARIA; MOLECULAR DOCKING; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; SCREENING; ANIMAL; CELL CULTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; HUMAN; METABOLISM;

MUS; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; CATALYTIC DOMAIN; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPTANOIC ACIDS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; ITRACONAZOLE; L-LACTATE DEHYDROGENASE; MALARIA; MICE; PLASMODIUM FALCIPARUM; PYRROLES; TRIAZOLES;

EID: 79960294141     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021237     Document Type: Article

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