8-Aminoquinolines active against blood stage Plasmodium falciparum in vitro inhibit hematin polymerization

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 3, 1999, Pages 598-602

  Vennerstrom, Jonathan L ^a   Nuzum, Edwin O ^b   Miller, Robert E ^b   Dorn, Arnulf ^c   Gerena, Lucia ^b   Dande, Prasad A ^a   Ellis, William Y ^b   Ridley, Robert G ^c   Milhous, Wilbur K ^b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

8 (4 AMINO 1 METHYLBUTYLAMINO) 5 HEXYLOXY 6 METHOXY 4 METHYLQUINOLINE; 8 AMINOQUINOLINE DERIVATIVE; CHLOROQUINE; HEMATIN; MEFLOQUINE; PRIMAQUINE; TAFENOQUINE; UNCLASSIFIED DRUG; WR 249420; WR 251855; WR 254715; WR 255740; WR 255821; WR 259841; WR 266848; WR 268379; WR 268499; WR 268648; WR 268658; WR 55821; WR 59841;

ANTIMALARIAL ACTIVITY; ARTICLE; CROSS RESISTANCE; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; MALARIA; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN POLYMERIZATION;

EID: 0032982103     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.3.598     Document Type: Article

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