Interaction between interleukin-1 receptor 2 and Toll-like receptor 4, and cervical cytokines

Journal of Reproductive Immunology

Volumn 90, Issue 2, 2011, Pages 220-226

  Ryckman, Kelli K ^a,b   Williams, Scott M ^a   Krohn, Marijane A ^c,d   Simhan, Hyagriv N ^b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d Division of Infectious Disease   (United States)

Author keywords

Bacterial vaginosis; Cytokine concentrations; Ethnic disparity

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR 2; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AFRICAN AMERICAN; ARTICLE; FEMALE; GARDNERELLA VAGINALIS; GENE FREQUENCY; GENE INTERACTION; GENE LOCUS; GENETIC VARIABILITY; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AFRICAN AMERICANS; CERVIX UTERI; CYTOKINES; EPISTASIS, GENETIC; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; RECEPTORS, INTERLEUKIN-1 TYPE II; TOLL-LIKE RECEPTOR 4; VAGINOSIS, BACTERIAL;

EID: 79960261807     PISSN: 01650378     EISSN: 18727603     Source Type: Journal    
DOI: 10.1016/j.jri.2011.03.007     Document Type: Article

References (41)

1. Akira S., Takeda K., Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2001, 2(8):675-680.
2. Barreiro L.B., Ben-Ali M., Quach H., Laval G., Patin E., Pickrell J.K., Bouchier C., Tichit M., Neyrolles O., Gicquel B., Kidd J.R., Kidd K.K., Alcais A., Ragimbeau J., Pellegrini S., Abel L., Casanova J.L., Quintana-Murci L. Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense. PLoS Genet. 2009, 5(7):e1000562.
3. Basso B., Gimenez F., Lopez C. IL-1beta, IL-6 and IL-8 levels in gyneco-obstetric infections. Infect. Dis. Obstet. Gynecol. 2005, 13(4):207-211.
4. Benjamini Y., Hochberg Y. Controlling the false discovery rate-a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B: Methodol. 1995, 57(1):289-300.
5. Blake G.J., Ridker P.M. C-reactive protein and other inflammatory risk markers in acute coronary syndromes. J. Am. Coll. Cardiol. 2003, 41(4 Suppl. S):37S-42S.
6. Cauci S., Guaschino S., De A.D., Driussi S., De S.D., Penacchioni P., Quadrifoglio F. Interrelationships of interleukin-8 with interleukin-1beta and neutrophils in vaginal fluid of healthy and bacterial vaginosis positive women. Mol. Hum. Reprod. 2003, 9(1):53-58.
7. Cauci S., Di S.M., Casabellata G., Ryckman K., Williams S.M., Guaschino S. Association of interleukin-1beta and interleukin-1 receptor antagonist polymorphisms with bacterial vaginosis in non-pregnant Italian women. Mol. Hum. Reprod. 2007, 13(4):243-250.
8. El-Bastawissi A.Y., Williams M.A., Riley D.E., Hitti J., Krieger J.N. Amniotic fluid interleukin-6 and preterm delivery: a review. Obstet. Gynecol. 2000, 95(6 Pt 2):1056-1064.
9. Engel S.A., Erichsen H.C., Savitz D.A., Thorp J., Chanock S.J., Olshan A.F. Risk of spontaneous preterm birth is associated with common proinflammatory cytokine polymorphisms. Epidemiology 2005, 16(4):469-477.
10. Fidel P.L. Immune regulation and its role in the pathogenesis of Candida vaginitis. Curr. Infect. Dis. Rep. 2003, 5(6):488-493.
11. Genc M.R., Onderdonk A.B., Vardhana S., Delaney M.L., Norwitz E.R., Tuomala R.E., Paraskevas L.R., Witkin S.S. Polymorphism in intron 2 of the interleukin-1 receptor antagonist gene, local midtrimester cytokine response to vaginal flora, and subsequent preterm birth. Am. J. Obstet. Gynecol. 2004, 191(4):1324-1330.
12. Goepfert A.R., Varner M., Ward K., MacPherson C., Klebanoff M., Goldenberg R.L., Mercer B., Meis P., Iams J., Moawad A., Carey J.C., Leveno K., Wapner R., Caritis S.N., Miodovnik M., Sorokin Y., O'Sullivan M.J., Van Dorsten J.P., Langer O. Differences in inflammatory cytokine and Toll-like receptor genes and bacterial vaginosis in pregnancy. Am. J. Obstet. Gynecol. 2005, 193(4):1478-1485.
13. Hedges S.R., Barrientes F., Desmond R.A., Schwebke J.R. Local and systemic cytokine levels in relation to changes in vaginal flora. J. Infect. Dis. 2006, 193(4):556-562.
14. Hoffmann S.C., Stanley E.M., Cox E.D., DiMercurio B.S., Koziol D.E., Harlan D.M., Kirk A.D., Blair P.J. Ethnicity greatly influences cytokine gene polymorphism distribution. Am. J. Transplant. 2002, 2(6):560-567.
15. Imseis H.M., Greig P.C., Livengood C.H., Shunior E., Durda P., Erikson M. Characterization of the inflammatory cytokines in the vagina during pregnancy and labor and with bacterial vaginosis. J. Soc. Gynecol. Investig. 1997, 4(2):90-94.
16. Kramer M.S., Goulet L., Lydon J., Seguin L., McNamara H., Dassa C., Platt R.W., Chen M.F., Gauthier H., Genest J., Kahn S., Libman M., Rozen R., Masse A., Miner L., Asselin G., Benjamin A., Klein J., Koren G. Socio-economic disparities in preterm birth: causal pathways and mechanisms. Paediatr. Perinat. Epidemiol. 2001, 15(Suppl. 2):104-123.
17. Kurki T., Sivonen A., Renkonen O.V., Savia E., Ylikorkala O. Bacterial vaginosis in early pregnancy and pregnancy outcome. Obstet. Gynecol. 1992, 80(2):173-177. (Available from 1992).
18. Macones G.A., Parry S., Elkousy M., Clothier B., Ural S.H., Strauss J.F. A polymorphism in the promoter region of TNF and bacterial vaginosis: preliminary evidence of gene-environment interaction in the etiology of spontaneous preterm birth. Am. J. Obstet. Gynecol. 2004, 190(6):1504-1508.
19. Mattsby-Baltzer I., Platz-Christensen J.J., Hosseini N., Rosen P. IL-1beta, IL-6, TNFalpha, fetal fibronectin, and endotoxin in the lower genital tract of pregnant women with bacterial vaginosis. Acta Obstet. Gynecol. Scand. 1998, 77(7):701-706.
20. Menon R., Williams S.M., Fortunato S.J. Amniotic fluid interleukin-1beta and interleukin-8 concentrations: racial disparity in preterm birth. Reprod. Sci. 2007, 14(3):253-259.
21. Menon R., Camargo M.C., Thorsen P., Lombardi S.J., Fortunato S.J. Amniotic fluid interleukin-6 increase is an indicator of spontaneous preterm birth in white but not black Americans. Am. J. Obstet. Gynecol. 2008, 198(1):77.
22. Menon R., Thorsen P., Vogel I., Jacobsson B., Morgan N., Jiang L., Li C., Williams S.M., Fortunato S.J. Racial disparity in amniotic fluid concentrations of tumor necrosis factor (TNF)-alpha and soluble TNF receptors in spontaneous preterm birth. Am. J. Obstet. Gynecol. 2008, 198(5):510-533.
23. Menon R., Velez D.R., Morgan N., Lombardi S.J., Fortunato S.J., Williams S.M. Genetic regulation of amniotic fluid TNF-alpha and soluble TNF receptor concentrations affected by race and preterm birth. Hum. Genet. 2008, 124(3):243-253.
24. Myslobodsky M. Preterm delivery: on proxies and proximal factors. Paediatr. Perinat. Epidemiol. 2001, 15(4):381-383.
25. Ness R.B. The consequences for human reproduction of a robust inflammatory response. Q. Rev. Biol. 2004, 79(4):383-393.
26. Ness R.B., Hillier S., Richter H.E., Soper D.E., Stamm C., Bass D.C., Sweet R.L., Rice P. Can known risk factors explain racial differences in the occurrence of bacterial vaginosis?. J. Natl. Med. Assoc. 2003, 95(3):201-212.
27. Nugent R.P., Krohn M.A., Hillier S.L. Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation. J. Clin. Microbiol. 1991, 29(2):297-301.
28. Platz-Christensen J.J., Mattsby-Baltzer I., Thomsen P., Wiqvist N. Endotoxin and interleukin-1 alpha in the cervical mucus and vaginal fluid of pregnant women with bacterial vaginosis. Am. J. Obstet. Gynecol. 1993, 169(5):1161-1166.
29. Pritchard J.K., Stephens M., Donnelly P. Inference of population structure using multilocus genotype data. Genetics 2000, 155(2):945-959.
30. Romero R., Avila C., Santhanam U., Sehgal P.B. Amniotic fluid interleukin 6 in preterm labor. Association with infection. J. Clin. Invest. 1990, 85(5):1392-1400.
31. Russell M., Sparling F., Morrison R. Mucosal immunology of sexually transmitted diseases. Mucosla Immunology 2004, Elsevier, Oxford. J. Mestecky, J. Bienenstock, M. Lamm (Eds.).
32. Ryckman K.K., Williams S.M., Kalinka J. Correlations of selected vaginal cytokine levels with pregnancy-related traits in women with bacterial vaginosis and mycoplasmas. J. Reprod. Immunol. 2008, 78(2):172-180.
33. Ryckman K.K., Williams S.M., Krohn M.A., Simhan H.N. Racial differences in cervical cytokine concentrations between pregnant women with and without bacterial vaginosis. J. Reprod. Immunol. 2008, 78(2):166-171.
34. Ryckman K.K., Williams S.M., Krohn M.A., Simhan H.N. Genetic association of Toll-like receptor 4 with cervical cytokine concentrations during pregnancy. Genes Immun. 2009, 10(7):636-640.
35. Silver H.M., Sperling R.S., St Clair P.J., Gibbs R.S. Evidence relating bacterial vaginosis to intraamniotic infection. Am. J. Obstet. Gynecol. 1989, 161(3):808-812.
36. Simhan H.N., Caritis S.N., Krohn M.A., Martinez de T.B., Landers D.V., Hillier S.L. Decreased cervical proinflammatory cytokines permit subsequent upper genital tract infection during pregnancy. Am. J. Obstet. Gynecol. 2003, 189(2):560-567.
37. Velez D.R., Menon R., Thorsen P., Jiang L., Simhan H., Morgan N., Fortunato S.J., Williams S.M. Ethnic differences in interleukin 6 (IL-6) and IL6 receptor genes in spontaneous preterm birth and effects on amniotic fluid protein levels. Ann. Hum. Genet. 2007, 71(Pt 5):586-600.
38. Velez D.R., Fortunato S.J., Williams S.M., Menon R. Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth. Hum. Mol. Genet. 2008, 17(11):1619-1630.
39. Wang Z.C., Hill J.A., Yunis E.J., Xiao L., Anderson D.J. Maternal CD46H 2 and IL1B-511 1 homozygosity in T helper 1-type immunity to trophoblast antigens in recurrent pregnancy loss. Hum. Reprod. 2006, 21(3):818-822.
40. Wasiela M., Krzeminski Z., Kalinka J., Brzezinska-Blaszczyk E. Correlation between levels of selected cytokines in cervico-vaginal fluid of women with abnormal vaginal bacterial flora. Med. Dosw. Mikrobiol. 2005, 57(3):327-333.
41. Williams S.M., Velez D.R., Menon R. Geographic ancestry and markers of preterm birth. Expert Rev. Mol. Diagn. 2010, 10(1):27-32.