IL-1β, IL-6, TNFα, fetal fibronectin and endotoxin in the lower genital tract of pregnant women with bacterial vaginosis

Acta Obstetricia et Gynecologica Scandinavica

Volumn 77, Issue 7, 1998, Pages 701-706

  Mattsby Baltzer, Inger ^a   Platz Christensen, Jens J ^a   Hosseini, Nosrat ^a   Rosén, Petra ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Bacterial vaginosis; Endotoxin; Fetal fibronectin; Interleukin 1 ; Interleukin 6; Tumor necrosis factor

Indexed keywords

CYTOKINE; ENDOTOXIN; FIBRONECTIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; INTERLEUKIN 1;

ABORTION; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME IMMUNOASSAY; FEMALE; FEMALE GENITAL SYSTEM; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN TISSUE; MONOCYTE; PREVOTELLA; PRIORITY JOURNAL; UTERINE CERVIX MUCUS; VAGINA DISCHARGE; VAGINITIS; BACTERIAL INFECTION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PREGNANCY; PREGNANCY COMPLICATION;

ADULT; BACTEROIDACEAE INFECTIONS; CERVIX MUCUS; ENDOTOXINS; FEMALE; FIBRONECTINS; GENITALIA, FEMALE; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREGNANCY TRIMESTER, FIRST; PREVOTELLA; TUMOR NECROSIS FACTOR-ALPHA; VAGINOSIS, BACTERIAL;

EID: 0031596065     PISSN: 00016349     EISSN: None     Source Type: Journal    
DOI: 10.1080/j.1600-0412.1998.770701.x     Document Type: Article

References (25)

1. Holst E, Rossel Goffeng A, Andersch B. Bacterial vaginosis and vaginal microorganisms in idiopathic premature labor and association with pregnancy outcome. J Clin Microbiol 1994; 32: 176-86.
2. Martius J, Eschenbach DA. The role of bacterial vaginosis as a cause of amniotic fluid infection, chorioamnionitis and prematurity - a review. Arch Gynecol Obstet 1990; 247: 1-13.
3. Hillier SL, Nugent RP, Eschenbach DA, Krohn MA, Gibbs RS, Martin DH et al. Association between bacterial vaginosis and preterm delivery of a lowbirth-weight infant. N Eng J Med 1995; 333: 1737-42.
4. Kurki T, Sivonen A, Renkonen O-V, Savia E, Ylikorkala O. Bacterial vaginosis in early pregnancy and pregnancy outcome. Obstet Gynecol 1992; 80: 173-7.
5. Sjöberg I, Håkansson S. Endotoxin in vaginal fluid of women with bacterial vaginosis. Obstet Gynecol 1991; 77: 265-6.
6. Krohn M, Hillier SL, Lee ML, Rabe LK, Eschenbach DA. Vaginal bacteroides species are associated with an increased rate of preterm delivery among women in preterm labor. J Infect Dis 1991; 164: 88-93.
7. Platz-Christensen JJ, Mattsby-Baltzer I, Thomsen P, Wiqvist N. Endotoxin and interleukin-1 in the cervical mucus and vaginal fluid of pregnant women with bacterial vaginosis. Am J Obstet Gynecol 1993; 169: 1161-6.
8. Morrison DC, Ryan JL. Endotoxins and disease mechanisms. Ann Rev Med 1987; 38: 417-32.
9. Amsel R, Totten PA, Spiegel CA, Chen KCS, Eschenbach D, Holmes KK. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med 1983; 74: 14-22.
10. Mattsby-Baltzer I, Roseanu A, Motas C, Elverfors J, Engberg I, Hanson LA. Lactoferrin or a fragment thereof inhibits the endotoxin-induced IL-6 response in human monocytic cells. Pediatr Res 1996; 40: 257-62.
11. Golenbock DT, Lynn WA, Hampton RY, Millham FH, Liu Y. Characterization of LPS signaling pathways with the LPS inhibitors lipid IVa (IA, LA-14-pp) and Rhodobacter sphaeroides lipid A. In: Levin J, Alving CR, Munford RS, Stutz PL, editors. Bacterial endotoxin: Recognition and effector mechanisms. Amsterdam, Elsevier Science Publishers BV, 1993: 349-59.
12. Strittmatter W, Weckesser J, Salimath PV, Galanos C. Non-toxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023. J Bacteriol 1983; 155: 153-8.
13. Westphal O, Jann K. Bacterial lipopolysaccharides. Extraction with phenol-water and further applications of the procedure. In: Whistler RL, ed. Methods in carbohydrate chemistry. AP. Inc., London. Chemistry Vol. 5, 1965: 83-91.
14. Tabibzadeh S, Sun XZ. Cytokine expression in human endometrium throughout the menstrual cycle. Hum Reprod 1992; 7: 1214-21.
15. Tamatani T, Tsunoda H, Iwasaki H, Kaneko M, Hashimoto T, Onozaki K. Existence of both IL-1α and β in normal human amniotic fluid: Unique high molecular weight form of IL-1β. Immunology 1988; 65: 337-42.
16. Romero R, Brody DT, Oyarzun E, Mazor M, Wu YK, Hobbins JC et al. Infection and labor. III. Interleukin-1: a signal for the onset of parturition. Am J Obstet Gynecol 1989; 160: 1117-23.
17. Kauma S, Dennis M, Strom S, Eierman D, Turner BS. Interleukin-1β, human leukocyte antigen HLA-DR and transforming growth factor-β expression in endometrium, placenta and placental membranes. Am J Obstet Gynecol 1990; 163: 1430-7.
18. Mitchell MD, Edwin S, Romero RJ. Prostaglandin biosynthesis by human decidual cells: effects of inflammatory mediators. Prostaglandins leukotrienes and essential fatty acids. 1990; 41: 35-8.
19. Romero R, Wu YK, Brody DT, Oyarzun E, Duff GW Durum SK. Human decidua: a source of interleukin-1. Obstet Gynecol 1989; 73: 31-4.
20. Hay PE, Lamont RF, Taylor-Robinson D, Morgan DJ, Ison C, Pearson J. Abnormal bacterial colonization of the genital tract and subsequent preterm delivery and late miscarriage. BMJ 1994; 308: 295-8.
21. Inglis ST, Jeremias J, Kuno K, Lescale K, Peeper Q, Chervenak FA et al. Detection of tumor necrosis factor-α, interleukin-6, and fetal fibronectin in the lower genital tract during pregnancy: Relation to outcome. Am J Obstet Gynecol 1994; 171: 5-10.
22. Mattsby-Baltzer I, Hosseini N. The IL-6 response in human cervix epithelial and monocytic cell lines stimulated by bacteria associated with bacterial vaginosis and Escherichia coli. Inter J STD & AIDS 1997; 8 (suppl 1): 34.
23. Lockwood CJ, Senyei AE, Dische R, Casal D, Shah KD, Thung SU et al. Fetal fibronectin in cervical and vaginal secretions as a predictor of preterm delivery. N Eng J Med 1991; 325: 669-74.
24. Goldenberg R, Thom E, Moawad A, Johnson F, Roberts J, Caritis S. The preterm prediction study: fetal fibronectin, bacterial vaginosis, and peripartum infection. Obstet Gynecol 1996; 87: 656-60.
25. Rossel Goffeng A, Holst E, Milsom I, Lindstedt G, Lundberg P-A, Andersch B. Fetal fibronectin and microrganisms in vaginal fluid of healthy pregnant women. Acta Obstet Gynecol Scand 1996; 75: 520-5.