Differences in inflammatory cytokine and Toll-like receptor genes and bacterial vaginosis in pregnancy

American Journal of Obstetrics and Gynecology

Volumn 193, Issue 4, 2005, Pages 1478-1485

  Goepfert, Alice R ^a   Varner, Michael ^b   Ward, Kenneth ^b   Macpherson, Cora ^c   Klebanoff, Mark ^d   Goldenberg, Robert L ^a   Mercer, Brian ^e   Meis, Paul ^f   Iams, Jay ^g   Moawad, Atef ^h   Carey, J Chris ⁱ   Leveno, Kenneth ^j   Wapner, Ronald ^k   Caritis, Steve N ^l   Miodovnik, Menachem ^m   Sorokin, Yoram ⁿ   O'Sullivan, Mary J ^o   Van Dorsten, J Peter ^p   Langer, Oded ^q  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^e UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^f WAKE FOREST UNIVERSITY   (United States)

^g OHIO STATE UNIVERSITY   (United States)

^h UNIVERSITY OF CHICAGO   (United States)

ⁱ UNIVERSITY OF OKLAHOMA   (United States)

^j UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^k THOMAS JEFFERSON UNIVERSITY   (United States)

^l UNIVERSITY OF PITTSBURGH   (United States)

^m UNIVERSITY OF CINCINNATI   (United States)

ⁿ WAYNE STATE UNIVERSITY   (United States)

^o UNIVERSITY OF MIAMI   (United States)

^p MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^q UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

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Author keywords

Bacterial vaginosis; Cytokine gene polymorphism; Pregnancy; Toll like receptor gene polymorphism

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANALYTIC METHOD; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DETERMINATION; DNA EXTRACTION; EXON; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC POLYMORPHISM; GENOTYPE; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; PREGNANCY; PRIORITY JOURNAL; RISK ASSESSMENT; VAGINITIS;

ADULT; BACTERIAL INFECTIONS; FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RECEPTORS, CYTOKINE; TOLL-LIKE RECEPTORS; VAGINA; VAGINAL DISEASES;

EID: 25844486051     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2005.03.053     Document Type: Article

References (26)

1. D.A. Eschenbach Bacterial vaginosis and anaerobes in obstetric- gynecologic infection Clin Infect Dis 16 1993 S282 S287
2. J.C. Hauth, R.L. Goldenberg, W.W. Andrews, M.B. DuBard, and R.L. Copper Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis N Engl J Med 333 1995 1732 1736
3. G.B. Hill The microbiology of bacterial vaginosis Am J Obstet Gynecol 169 1993 450 454
4. R.P. Nugent, M.A. Krohn, and S.L. Hillier Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation J Clin Microbiol 29 1991 297 301
5. H. Leitich, B. Bodner-Adler, M. Brunbauer, A. Kaider, C. Egarter, and P. Husslein Bacterial vaginosis as a risk factor for preterm delivery: a meta-analysis Am J Obstet Gynecol 189 2003 139 147
6. R.L. Goldenberg, J.C. Hauth, and W.W. Andrews Intrauterine infection and preterm delivery N Engl J Med 342 2000 1500 1507
7. J. Schwebke Gynecologic consequences of bacterial vaginosis Obstet Gynecol Clin N Am 30 2003 685 694
8. R.L. Goldenberg, S.P. Cliver, F.X. Mulvihill, C.A. Hickey, H.J. Hoffman, and L.V. Klerman Medical, psychosocial, and behavioral risk factors do not explain the increased risk for low birth weight among black women Am J Obstet Gynecol 175 1996 1317 1324
9. S.J. Ventura, J.A. Martin, S.C. Curtin, T.J. Mathews, and M.M. Park Births: final data for 1998 Nat Vital Stat Rep 48 2000 1 100
10. R.L. Goldenberg, J.D. Iams, B.M. Mercer, P.J. Meis, A.H. Moawad, and R.L. Copper The preterm prediction study: the value of new vs standard risk factors in predicting early and all spontaneous preterm births. NICHD MFMU Network [see comment] Am J Public Health 88 1998 233 238
11. R.L. Goldenberg, M.A. Klebanoff, R. Nugent, M.A. Krohn, S. Hillier, and W.W. Andrews Bacterial colonization of the vagina during pregnancy in four ethnic groups: vaginal Infections and Prematurity Study Group Am J Obstet Gynecol 174 1996 1618 1621
12. P.J. Meis, R.L. Goldenberg, B.M. Mercer, J.D. Iams, A.H. Moawad, and M. Miodovnik Preterm prediction study: is socioeconomic status a risk factor for bacterial vaginosis in black or in white women? Am J Perinatol 17 2000 41 45
13. S. Cauci, J. Hitti, C. Noonan, K. Agnew, F. Quadrifoglio, and S.L. Hillier Vaginal hydrolytic enzymes, immunoglobulin A against Gardnerella vaginalis toxin, and risk of early preterm birth among women in preterm labor with bacterial vaginosis or intermediate flora Am J Obstet Gynecol 187 2002 877 881
14. J.C. Hauth, C. Macpherson, J.C. Carey, M.A. Klebanoff, S.L. Hillier, and J.M. Ernest Early pregnancy threshold vaginal pH and Gram stain scores predictive of subsequent preterm birth in asymptomatic women Am J Obstet Gynecol 188 2003 831 835
15. M.H. Yudin, D.V. Landers, L. Meyn, and S.L. Hillier Clinical and cervical cytokine response to treatment with oral or vaginal metronidazole for bacterial vaginosis during pregnancy: a randomized trial Obstet Gynecol 102 2003 527 534
16. J. Bidwell, L. Keen, G. Gallagher, R. Kimberly, T. Huizinga, and M.F. McDermott Cytokine gene polymorphism in human disease: on-line databases Genes Immun 1 1999 3 19
17. J. Bidwell, L. Keen, G. Gallagher, R. Kimberly, T. Huizinga, and M.F. McDermott Cytokine gene polymorphism in human disease: on-line databases, supplement 1 [see comment] Genes Immun 2 2001 61 70
18. N. Haukim, J.L. Bidwell, A.J. Smith, L.J. Keen, G. Gallagher, and R. Kimberly Cytokine gene polymorphism in human disease: on-line databases, supplement 2 Genes Immun 3 2002 313 330
19. R. Medzhitov Toll-like receptors and innate immunity Nat Rev Immunol 1 2001 135 145
20. S.R. Krutzik, P.A. Sieling, and R.L. Modlin The role of Toll-like receptors in host defense against microbial infection Curr Opin Immunol 13 2001 104 108
21. N.C. Arbour, E. Lorenz, B.C. Schutte, J. Zabner, J.N. Kline, and M. Jones TLR4 mutations are associated with endotoxin hyporesponsiveness in humans Nat Genet 25 2000 187 191
22. O. Michel, T.D. LeVan, D. Stern, M. Dentener, J. Thom, and D. Gnat Systemic responsiveness to lipopolysaccharide and polymorphisms in the Toll-like receptor 4 gene in human beings J Allergy Clin Immunol 112 2003 923 929
23. R.L. Goldenberg, B.M. Mercer, P.J. Meis, R.L. Copper, A. Das, and D. McNellis The preterm prediction study: fetal fibronectin testing and spontaneous preterm birth. NICHD Maternal Fetal Medicine Units Network Obstet Gynecol 87 1996 643 648
24. J.C. Carey, M.A. Klebanoff, J.C. Hauth, S.L. Hillier, E.A. Thom, and J.M. Ernest Metronidazole to prevent preterm delivery in pregnant women with asymptomatic bacterial vaginosis. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units N Engl J Med 342 2000 532 540
25. M. Varner The NICHD MFMU Network. The association of inflammatory cytokine and Toll-like receptor gene polymorphisms with spontaneous preterm birth J Soc Gynecol Investig 11 2004 310A
26. D.A. Eschenbach History and review of bacterial vaginosis Am J Obstet Gynecol 169 1993 441 445