Scavenger receptor SR-BI in macrophage lipid metabolism

Atherosclerosis

Volumn 217, Issue 1, 2011, Pages 106-112

  Ji, Ailing ^b,c   Meyer, Jason M ^b,c   Cai, Lei ^b,c   Akinmusire, Akinwunmi ^c   de Beer, Maria C ^b,c   Webb, Nancy R ^b,c   van der Westhuyzen, Deneys R ^a,b,c  

^a LEXINGTON VA MEDICAL CENTER   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

ABCA1; ABCG1; Cholesterol efflux; HDL; Macrophage; SR BI

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; CD36 ANTIGEN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED HIGH DENSITY LIPOPROTEIN BINDING PROTEIN 1; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SCAVENGER RECEPTOR A; SCAVENGER RECEPTOR BI; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BONE MARROW CELL; CELL DIFFERENTIATION; CELL SURFACE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; LIPID METABOLISM; MACROPHAGE; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

ANIMALS; ANTIGENS, CD36; ATHEROSCLEROSIS; BIOTINYLATION; CHOLESTEROL; GLYCOSYLPHOSPHATIDYLINOSITOLS; HOMEOSTASIS; LIPID METABOLISM; LIPOPROTEINS; LIPOPROTEINS, HDL; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTORS, LIPOPROTEIN;

EID: 79960242055     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.03.017     Document Type: Article

References (44)

1. Acton S., Rigotti A., Landschulz K.T., Xu S., Hobbs H.H., Krieger M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 1996, 271:518-520.
2. Rigotti A., Miettinen H.E., Krieger M. The role of the high-density lipoprotein receptor SR-BI in the lipid metabolism of endocrine and other tissues. Endocr Rev 2003, 24:357-387.
3. Cai L., Ji A., de Beer F.C., Tannock L.R., van der Westhuyzen D.R. SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance. J Clin Invest 2008, 118:364-375.
4. Rigotti A., Trigatti B.L., Penman M., Rayburn H., Herz J., Krieger M. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proc Natl Acad Sci USA 1997, 94:12610-12615.
5. Ji Y., Jian B., Wang N., et al. Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux. J Biol Chem 1997, 272:20982-20985.
6. Dole V.S., Matuskova J., Vasile E., et al. Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol 2008, 28:1111-1116.
7. Van Eck M., Hoekstra M., Hildebrand R.B., et al. Increased oxidative stress in scavenger receptor BI knockout mice with dysfunctional HDL. Arterioscler Thromb Vasc Biol 2007, 27:2413-2419.
8. Yuhanna I.S., Zhu Y., Cox B.E., et al. High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase. Nat Med 2001, 7:853-857.
9. Li X.A., Guo L., Dressman J.L., Asmis R., Smart E.J. A novel ligand-independent apoptotic pathway induced by scavenger receptor class B, type I and suppressed by endothelial nitric-oxide synthase and high density lipoprotein. J Biol Chem 2005, 280:19087-19096.
10. Varban M.L, Rinninger F., Wang N., et al. Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol. Proc Natl Acad Sci USA 1998, 95:4619-4624.
11. Zhang Y., Da Silva J.R., Reilly M., Billheimer J.T., Rothblat G.H., Rader D.J. Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo. J Clin Invest 2005, 115:2870-2874.
12. Braun A., Trigatti B.L., Post M.J., et al. Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice. Circ Res 2002, 90:270-276.
13. Huszar D, Varban M.L., Rinninger F., et al. Increased LDL, cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1. Arterioscler Thromb Vasc Biol 2000, 20:1068-1073.
14. Kozarsky K.F., Donahee M.H., Glick J.M., Krieger M., Rader D.J. Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse. Arterioscler Thromb Vasc Biol 2000, 20:721-727.
15. Huby T., Doucet C., Dachet C., et al. Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues. J Clin Invest 2006, 116:2767-2776.
16. Hirano K., Yamashita S., Nakagawa Y., et al. Expression of human scavenger receptor class B type I in cultured human monocyte-derived macrophages and atherosclerotic lesions. Circ Res 1999, 85:108-116.
17. Zhang W., Yancey P.G., Su Y.R., et al. Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice. Circulation 2003, 108:2258-2263.
18. Covey S.D., Krieger M., Wang W., Penman M., Trigatti B.L. Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptor-negative mice involves its expression in bone marrow-derived cells. Arterioscler Thromb Vasc Biol 2003, 23:1589-1594.
19. Van Eck M., Bos I.S., Hildebrand R.B., Van Rij B.T., Van Berkel T.J. Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development. Am J Pathol 2004, 165:785-794.
20. Adorni M.P, Zimetti F., Billheimer J.T., et al. The roles of different pathways in the release of cholesterol from macrophages. J Lipid Res 2007, 48:2453-2462.
21. de la Llera-Moya M., Rothblat G.H., Connelly M.A., et al. Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface. J Lipid Res 1999, 40:575-580.
22. Yona S., Heinsbroek S.E., Peiser L., Gordon S., Perretti M., Flower R.J. Impaired phagocytic mechanism in annexin 1 null macrophages. Br J Pharmacol 2006, 148:469-477.
23. de Villiers W.J., Cai L., Webb N.R., de Beer M.C., van der Westhuyzen D.R., de Beer F.C. CD36 does not play a direct role in HDL or LDL metabolism. J Lipid Res 2001, 42:1231-1238.
24. Carr T.P., Andresen C.J., Rudel L.L. Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts. Clin Biochem 1993, 26:39-42.
25. Eckhardt E.R, Cai L., Sun B., Webb N.R., van der Westhuyzen D.R. High density lipoprotein uptake by scavenger receptor SR-BII. J Biol Chem 2004, 279:14372-14381.
26. Coetzee G.A., Strachan A.F., van der Westhuyzen D.R., Hoppe H.C., Jeenah M.S., de Beer F.C. Serum amyloid A-containing human high density lipoprotein 3. Density, size, and apolipoprotein composition. J Biol Chem 1986, 261:9644-9651.
27. Lowry O.H, Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 1951, 193:265-275.
28. Traenkel-Conrat H. Methods for investigating the essential groups for enzymatic activity. Methods Enzymol 1957, 4:247-269.
29. van der Westhuyzen D.R., Cai L., de Beer M.C., de Beer F.C. Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I. J Biol Chem 2005, 280:35890-35895.
30. Yancey P.G., de la Llera-Moya M., Swarnakar S., et al. High density lipoprotein phospholipid composition is a major determinant of the bi-directional flux and net movement of cellular free cholesterol mediated by scavenger receptor BI. J Biol Chem 2000, 275:36596-36604.
31. Hirsch S., Austyn J.M., Gordon S. Expression of the macrophage-specific antigen F4/80 during differentiation of mouse bone marrow cells in culture. J Exp Med 1981, 154:713-725.
32. Murray P.J., Wynn T.A. Obstacles and opportunities for understanding macrophage polarization. J Leukoc Biol 2011.
33. Venkateswaran A., Laffitte B.A., Joseph S.B., et al. Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. Proc Natl Acad Sci USA 2000, 97:12097-12102.
34. Ioka R.X., Kang M.J., Kamiyama S., et al. Expression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1. J Biol Chem 2003, 278:7344-7349.
35. Favari E., Calabresi L., Adorni M.P., et al. Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1. Biochemistry 2009, 48:11067-11074.
36. Trogan E., Feig J.E., Dogan S., et al. Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. Proc Natl Acad Sci USA 2006, 103:3781-3786.
37. Yu L., Cao G., Repa J., Stangl H. Sterol regulation of scavenger receptor class B type I in macrophages. J Lipid Res 2004, 45:889-899.
38. Brundert M., Heeren J., Bahar-Bayansar M., Ewert A., Moore K.J., Rinninger F. Selective uptake of HDL cholesteryl esters and cholesterol efflux from mouse peritoneal macrophages independent of SR-BI. J Lipid Res 2006, 47:2408-2421.
39. Shetty S., Eckhardt E.R., Post S.R., van der Westhuyzen D.R. Phosphatidylinositol-3-kinase regulates scavenger receptor class B type I subcellular localization and selective lipid uptake in hepatocytes. Arterioscler Thromb Vasc Biol 2006, 26:2125-2131.
40. Yvan-Charvet L., Bobard A., Bossard P., et al. In vivo evidence for a role of adipose tissue SR-BI in the nutritional and hormonal regulation of adiposity and cholesterol homeostasis. Arterioscler Thromb Vasc Biol 2007, 27:1340-1345.
41. Bultel S., Helin L., Clavey V., et al. Liver X receptor activation induces the uptake of cholesteryl esters from high density lipoproteins in primary human macrophages. Arterioscler Thromb Vasc Biol 2008, 28:2288-2295.
42. Wang X., Collins H.L., Ranalletta M., et al. Macrophage ABCA1 and ABCG1, but not SR-BI promote macrophage reverse cholesterol transport in vivo. J Clin Invest 2007, 117:2216-2224.
43. Yvan-Charvet L., Pagler T.A., Wang N., et al. SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL. J Lipid Res 2008, 49:107-114.
44. Zhao Y., Pennings M., Hildebrand R.B., et al. Enhanced foam cell formation, atherosclerotic lesion development, and inflammation by combined deletion of abca1 and sr-bi in bone marrow-derived cells in ldl receptor knockout mice on western-type diet. Circ Res 2010.