Down-regulation of the ubiquitin-proteasome proteolysis system by amino acids and insulin involves the adenosine monophosphate-activated protein kinase and mammalian target of rapamycin pathways in rat hepatocytes

Amino Acids

Volumn 41, Issue 2, 2011, Pages 457-468

  Chotechuang, Nattida ^a,b   Azzout Marniche, Dalila ^a,b   Bos, Cécile ^a,b   Chaumontet, Catherine ^a,b   Gaudichon, Claire ^a,b   Tomé, Daniel ^a,b  

^a AGROPARISTECH   (France)

^b INRA Institut National de la Recherche Agronomique   (France)

Author keywords

AMPK; High protein diet; Liver; mTOR; Protein degradation

Indexed keywords

AMINO ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEASOME; UBIQUITINATED PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DIET; PROTEIN EXPRESSION; PROTEIN INTAKE; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UBIQUITINATION;

AMINO ACIDS; AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DIETARY PROTEINS; DOWN-REGULATION; GENE EXPRESSION PROFILING; HEPATOCYTES; HYPOGLYCEMIC AGENTS; INSULIN; MALE; ORGAN SIZE; PHOSPHORYLATION; POSTPRANDIAL PERIOD; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, WISTAR; RIBONUCLEOTIDES; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES; UBIQUITIN; UBIQUITINATED PROTEINS; UBIQUITINATION;

MAMMALIA; RATTUS;

EID: 79960228945     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-010-0765-2     Document Type: Article

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