Fluid flow induced calcium response in osteoblasts: Mathematical modeling

Journal of Biomechanics

Volumn 44, Issue 11, 2011, Pages 2040-2046

  Su, J H ^a   Xu, F ^a,b   Lu, X L ^c   Lu, T J ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF DELAWARE   (United States)

Author keywords

ATP; Calcium concentration; Ion channel; Mathematical model; Purinergic receptor; Shear stress

Indexed keywords

BONE REMODELING; CALCIUM CONCENTRATION; CALCIUM RESPONSE; CONTROL GROUPS; DEVELOPED MODEL; EXPERIMENTAL DATA; EXPERIMENTAL SETUP; EXTRACELLULAR; EXTRACELLULAR ATP; FLUID SHEAR STRESS; INTRACELLULAR CALCIUM CONCENTRATION; ION CHANNEL; MAJOR FACTORS; MATHEMATICAL MODELING; MECHANOTRANSDUCTION; PRE-TREATMENT; PURINERGIC RECEPTORS; RELEASE PROCESS; RESPONSE PROCESS; SIMULATION RESULT;

BONE; COMPUTER SIMULATION; CONCENTRATION (PROCESS); ENZYME ACTIVITY; FLOW OF FLUIDS; FLUIDS; MATHEMATICAL MODELS; SHEAR FLOW; SHEAR STRESS;

CALCIUM;

ADENOSINE TRIPHOSPHATE; CALCIUM ION; ION CHANNEL; PURINERGIC RECEPTOR;

ARTICLE; BIOMECHANICS; CALCIUM SIGNALING; CELL LEVEL; CONTROLLED STUDY; CULTURE MEDIUM; EXPERIMENTAL STUDY; EXTRACELLULAR SPACE; FLUID FLOW; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE STUDY; THEORETICAL MODEL;

ADENOSINE TRIPHOSPHATE; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; ION CHANNELS; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; OSTEOBLASTS; RECEPTORS, PURINERGIC; SHEAR STRENGTH;

EID: 79960211025     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2011.05.004     Document Type: Article

References (46)

1. Allen F.D., Hung C.T., Pollack S.R., Brighton C.T. Serum modulates the intracellular calcium response of primary cultured bone cells to shear flow. Journal of Biomechanics 2000, 33:1585-1591.
2. Batra N., Li Y., Yellowley C., You L., Malone A., Kim C., Jacobs C. Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells. Journal of Biomechanics 2005, 38:1909-1917.
3. Bodin P., Burnstock G. Purinergic signalling: ATP release. Neurochemical Research 2001, 26:959-969.
4. Burnstock G. Purinergic signalling. British Journal of Pharmacology 2006, 147:S172-S181.
5. Baird Cheryl, L., Harkins Timothy, T., Morris Shayne, K., Lindsley Janet, E. Toppisomerase II drives DNA transport by hydrolyzing one ATP. Proceedings of the National Academy of Sciences 1999, 96:13685-13690.
6. David T. Wall shear stress modulation of ATP/ADP concentration at the endothelium. Annals of Biomedical Engineering 2003, 31:1231-1237.
7. Donahue S.W., Donahue H.J., Jacobs C.R. Osteoblastic cells have refractory periods for fluid-flow-induced intracellular calcium oscillations for short bouts of flow and display multiple low-magnitude oscillations during long-term flow. Journal of Biomechanics 2003, 36:35-43.
8. Donahue T., Haut T., Yellowley C., Donahue H., Jacobs C. Mechanosensitivity of bone cells to oscillating fluid flow induced shear stress may be modulated by chemotransport. Journal of Biomechanics 2003, 36:1363-1371.
9. Erb L., Liao Z.J., Seye C.I., Weisman G.A. P2 receptors: intracellular signaling. Pflugers Archiv-European Journal of Physiology 2006, 452:552-562.
10. Ferraro J., Daneshmand M., Bizios R., Rizzo V. Depletion of plasma membrane cholesterol dampens hydrostatic pressure and shear stress-induced mechanotransduction pathways in osteoblast cultures. American Journal of Physiology-Cell Physiology 2004, 286:831-839.
11. Francis M.J.O., Lees R.L., Trujillo E., Martin-Vasallo P., Heersche J.N.M., Mobasheri A. ATPase pumps in osteoclasts and osteoblasts. International Journal of Biochemistry and Cell Biology 2002, 34:459-476.
12. Frixione E., Porter R.M. Volume and surface changes of smooth endoplasmic-reticulum in crayfish retinula cells upon light-adaptation and dark-adaptation. Journal of Comparative Physiology A-Sensory Neural and Behavioral Physiology 1986, 159:667-674.
13. Gallagher J.A., Buckley K.A. Expression and function of P2 receptors in bone. Journal of Musculoskeletal Neuronal Interactions 2002, 2:432-439.
14. Genetos D.C., Geist D.J., Liu D.W., Donahue H.J., Duncan R.L. Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts. Journal of Bone and Mineral Research 2005, 20:41-49.
15. Geoffrey B., Timothy R.A. Nucleotides and regulation of bone cell function 2006, CRC Press, Boca Raton.
16. Hoebertz A., Mahendran S., Burnstock G., Arnett T.R. ATP and UTP at low concentrations strongly inhibit bone formation by osteoblasts: A novel role for the P2Y(2) receptor in bone remodeling. Journal of Cellular Biochemistry 2002, 86:413-419.
17. Hu X.Q., Xiang C., Cao L.L., Zhe X., Qin K.R. A mathematical model for ATP-mediated calcium, dynamics in vascular endothelial cells induced by fluid shear stress. Applied Mathematics and Mechanics-English Edition 2008, 29:1291-1298.
18. Hung C.T., Allen F.D., Pollack S.R., Brighton C.T. Intracellular Ca2+ stores and extracellular Ca2+ are required in the real-time Ca2+ response of bone cells experiencing fluid flow. Journal of Biomechanics 1996, 29:1411-1417.
19. Hung C.T., Pollack S.R., Reilly T.M., Brighton C.T. Real-time calcium response of cultured bone cell to fluid flow. Clinical Orthopaedics and Related Research 1995, 313:256-269.
20. Huo B., Lu X.L., Hung C.T., Costa D., Xu Q., Whitesides G.M., Guo X.E. Calcium responses in bone cell network induced by fluid flow. Biorheology 2008, 45. 107-107.
21. Jørgensen N.R., Henriksen Z., Sørensen O.H., Eriksen E.F., Civitelli R., Steinberg T.H. Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2×7 receptors. Journal of Biological Chemistry 2002, 277:7574-7580.
22. Jaramillo-Juarez F., Rodriguez-Vazquez M.L., Munoz-Martinez J., Quezada-Tristan T., Posadas del Rio F.A., Llamas-Viramontes J., Ortiz G.G., Feria-Velasco A., Reyes J.L. The ATP levels in kidneys and blood are mainly decreased by acute ingestion of tullidora (Karwinskia humboldtiana). Toxicon 2005, 46:99-103.
23. Kapela A., Bezerianos A., Tsoukias N.M. A mathematical model of Ca2+ dynamics in rat mesenteric smooth muscle cell: agonist and NO stimulation. Journal of Theoretical Biology 2008, 253:238-260.
24. Karaki H., Ozaki H., Hori M., Mitsui-Saito M., Amano K.-I., Harada K.-I., Miyamoto S., Nakazawa H., Won K.-J., Sato K. Calcium movements, distribution, and functions in smooth muscle. Pharmacological Reviews 1997, 49:157-230.
25. Katz S., Boland R., Santillán G. Modulation of ERK 1/2 and p38 MAPK signaling pathways by ATP in osteoblasts: involvement of mechanical stress-activated calcium influx, PKC, and Src activation. The International Journal of Biochemistry and Cell Biology 2006, 38:2082-2091.
26. Kizer N., Guo X.L., Hruska K. Reconstitution of stretch-activated cation channels by expression of the alpha-subunit of the epithelial sodium channel cloned from osteoblasts. Proceedings of the National Academy of Sciences of the United States of America 1997, 94:1013-1018.
27. Liu D.W., Genetos D.C., Shao Y., Geist D.J., Li J.L., Ke H.Z., Turner C.H., Duncan R.L. Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca2+- and ATP-dependent in MC3T3-E1 osteoblasts. Bone 2008, 42:644-652.
28. Mentaverri R., Kamel S., Brazier M. Involvement of capacitive calcium entry and calcium store refilling in osteoclastic survival and bone resorption process. Cell Calcium 2003, 34:169-175.
29. Nakano Y., Beertsen W., VanDenbos T., Kawamoto T., Oda K., Takano Y. Site-specific localization of two distinct phosphatases along the osteoblast plasma membrane: tissue non-specific alkaline phosphatase and plasma membrane calcium ATPase. Bone 2004, 35:1077-1085.
30. Nelson D.L., Cox M.M., Lehninger A.L. Principles of Biochemistry 2004, Freeman, New York.
31. Plank M.J., Wall D.J.N., David T. Atherosclerosis and calcium signalling in endothelial cells. Progress in Biophysics and Molecular Biology 2006, 91:287-313.
32. Plank M.J., Wall D.J.N., David T. The role of endothelial calcium and nitric oxide in the localisation of atherosclerosis. Mathematical Biosciences 2007, 207:26-39.
33. Ponik S.M., Triplett J.W., Pavalko F.M. Osteoblasts and osteocytes respond differently to oscillatory and unidirectional fluid flow profiles. Journal of Cellular Biochemistry 2007, 100:794-807.
34. Qin K.R., Xiang C., Xu Z., Cao L.L., Ge S.S., Jiang Z.L. Dynamic modeling for shear stress induced ATP release from vascular endothelial cells. Biomechanics and Modeling in Mechanobiology 2008, 7:345-353.
35. Riddle R.C., Taylor A.F., Rogers J.R., Donahue H.J. ATP release mediates fluid flow-induced proliferation of human bone marrow stromal cells. Journal of Bone and Mineral Research 2007, 22:589-600.
36. Romanello M., Pani B., Bicego M., DAndrea P. Mechanically induced ATP release from human osteoblastic cells. Biochemical and Biophysical Research Communications 2001, 289:1275-1281.
37. Riddle Ryan C, Jennifer A.F.T., Rogers R., Donahue Henry J ATP release mediates fluid flow-induced proliferation of human bone marrow stromal cells. Journal of Bone and Mineral Research 2007, 22:589-600.
38. Silva H.S., Kapela A., Tsoukias N.M. A mathematical model of plasma membrane electrophysiology and calcium dynamics in vascular endothelial cells. American Journal of Physiology-Cell Physiology 2007, 293:C277-C293.
39. Wang Jinhui, Xudong Huang, Weidong Huang A quantitative kinetic model for ATP-induced intracellular Ca2t oscillations. Journal of Theoretical Biology 2007, 245:510-519.
40. Wiesner T.F., Berk B.C., Nerem R.M. A mathematical model of the cytosolic-free calcium response in endothelial cells to fluid shear stress. Proceedings of the National Academy of Sciences of the United States of America 1997, 94:3726-3731.
41. Wong A.Y.K., Klassen G.A. A model of electrical-activity and cytosolic calcium dynamics in vascular endothelial-cells in response to fluid shear-stress. Annals of Biomedical Engineering 1995, 23:822-832.
42. Xu F., Lu T.J. Introduction to Skin Biothermomechanics and Thermal Pain. Springer/Science Press 2010.
43. Xu F., Lu T.J., Seffen K.A. Skin thermal pain modeling - a holistic method. J. Thermal Bio. 2008, 33:223-237.
44. Xu F., Wen T., Lu T.J., Seffen K.A. Modeling of nociceptor transduction in skin thermal pain sensation. J. Biomech. Eng. 2008, 130:041013.
45. You J., Jacobs C.R., Steinberg T.H., Donahue H.J. P2Y purinoceptors are responsible for oscillatory fluid flow-induced intracellular calcium mobilization in osteoblastic cells. Journal of Biological Chemistry 2002, 277:48724-48729.
46. Youm J.B., Han J., Kim N., Zhang Y.H., Kim E., Joo H., Leem C.H., Kim S.J., Cha K.A., Earm Y.E. Role of stretch-activated channels on the stretch-induced changes of rat atrial myocytes. Progress in Biophysics and Molecular Biology 2006, 90:186-206.