ATPase pumps in osteoclasts and osteoblasts

International Journal of Biochemistry and Cell Biology

Volumn 34, Issue 5, 2002, Pages 459-476

  Francis, Martin J O ^a   Lees, Rita L ^b   Trujillo, Elisa ^c   Martín Vasallo, Pablo ^c   Heersche, Johan N M ^b   Mobasheri, Ali ^d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSIDAD DE LA LAGUNA   (Spain)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Bone; Ca ATPase; Gastric H,K ATPase; Na,K ATPase; Osteoblast; Osteoclast; Osteocyte; Vacuolar H ATPase

Indexed keywords

CALCIUM; PHOSPHATE;

BONE ATROPHY; BONE CELL; BONE MATRIX; CALCIUM CELL LEVEL; CELL MEMBRANE TRANSPORT; CELL SPECIFICITY; CELL SURFACE; CELL TYPE; HOMEOSTASIS; HUMAN; MECHANICAL STIMULATION; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; PH; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BIOLOGICAL TRANSPORT; HOMEOSTASIS; HUMANS; ION PUMPS; MODELS, BIOLOGICAL; OSTEOBLASTS; OSTEOCLASTS;

EID: 0036129345     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(01)00142-X     Document Type: Review

References (148)

1. Structure and function of the P-type ATPases
2. The plasma membrane proton-translocating ATPase
3. Role of band 3 in homeostasis and cell shape
4. Activation of ion transport systems during cell volume regulation
5. Activation of ion transport pathways by changes in cell volume
6. Regulation of cytoplasmic pH in phagocytic cell function and dysfunction
7. Regulation of intracellular pH in alveolar epithelial cells
8. The Croonian lecture, 1983. Voltage-gated ion channels in the nerve membrane
9. The neuron as a dynamic electrogenic machine: Modulation of sodium-channel expression as a basis for functional plasticity in neurons
10. Sodium channels and their genes: Dynamic expression in the normal nervous system, dysregulation in disease states (1)
11. Calcium signalling: A historical account, recent developments and future perspectives
12. Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: Hormonal control
13. Regulation of the sodium pump in excitable cells
14. Sorting of ion transport proteins in polarized cells
15. The Ca-ATPase of the sarcoplasmic reticulum in skeletal and cardiac muscle. An overview from the very beginning to more recent prospects
16. Progress in the culture method of bone cells
17. The isolation and culture of cells from explants of human trabecular bone
18. Human osteoclast-like cells in primary culture
19. Ionic and hormonal control of calcium homeostasis
20. The bisphosphonate tiludronate is a potent inhibitor of the osteoclast vacuolar H-ATPase
21. Antiarrhythmic drugs and cardiac ion channels: Mechanisms of action
22. Molecular properties of brain sodium channels: An important target for anticonvulsant drugs
23. Ion transport in chondrocytes: Membrane transporters involved in intracellular ion homeostasis and the regulation of cell volume, free [Ca] and pH, free [Ca] and pH
24. Expression of cation exchanger NHE and anion exchanger AE isoforms in primary human bone derived osteoblasts
25. Effects of acute metabolic acidosis on parathyroid hormone action and calcium mobilization
26. Acidosis inhibits osteoblastic and stimulates osteoclastic activity in vitro
27. Stimulated osteoclastic and suppressed osteoblastic activity in metabolic but not respiratory acidosis
28. Molecular mechanisms of bone resorption: Therapeutic implications
29. The relationship of monocytic cells to the differentiation and resorption of bone
30. Bone resorption by osteoclasts
31. Molecular mechanisms of bone resorption by the osteoclast
32. The ultrastructure of the osteoclast and its functional implications
33. Some morphological observations on osteoclasts
34. Extracellular protons acidify osteoclasts, reduce cytosolic calcium, and promote expression of cell-matrix attachment structures
35. Clear zone in osteoclast function: Role of podosomes in regulation of bone-resorbing activity
36. Trafficking of matrix collagens through bone-resorbing osteoclasts
37. Removal of osteoclast bone resorption products by transcytosis
38. Osteoclastic acid transport: Mechanism and implications for physiological and pharmacological regulation
39. The osteoclast as a unicellular proton-transporting epithelium
40. Kinetic and cytochemical identification of osteoclast precursors and their differentiation into multinucleated osteoclasts
41. Histochemical demonstration of adenosine triphosphatase in osteoclasts
42. Localisation and distribution of adenosine triphosphatase activity in the femurs of young mice
43. Studies on the ultrastrucutral localization of adenosine triphosphatase activity in fracture callus
44. The locus of initial calcification in cartilage and bone
45. The cellular basis of bone remodelling: The quantum concept re-examined in light of recent advances in the cell biology of bone
46. Continuously growing bipotential and monopotential myogenic, adipogenic, and chondrogenic subclones isolated from the multipotential RCJ 3.1 clonal cell line
47. Isozymes of the Na,K-ATPase
48. Na,K-ATPase isozyme diversity: Comparative biochemistry and physiological implications of novel functional interactions
49. Evidence of a role for the Na,K-ATPase beta-subunit in active cation transport
50. An ultracytochemical investigation of ouabain-sensitive p-nitrophenylphosphatase in chick osteoclasts
51. +)ATPase in the plasma membrane of the osteoclast
52. + transport in urinary epithelia
53. + exchange in gastric glands as measured with a cytoplasmic-trapped, fluorescent pH indicator
54. Animal plasma membrane energization by proton-motive V-ATPases
55. Cell membrane amino acid transport processes in the domestic fowl (Gallus domesticus)
56. i) transport in Xenopus oocytes induced by mRNA from 1α,25-dihydroxyvitamin D3-treated rat osteoblast-like cells
57. Characteristics of phosphate transport into osteoblast-like cells
58. Direct effects of diphenylhydantoin (phenytoin) on the ion-transporting ATPases of cultured osteoblast-like cells
59. Human osteogenic sarcoma: Fine structural localization of adenosine triphosphatase
60. Expression of the neuronal α3 and α2 isoforms of the Na,K-ATPase in primary human bone derived osteoblasts
61. +-ATPase in primary human bone derived osteoblasts
62. Functional significance of the β-subunit for heterodimeric P-type ATPases
63. Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: Effect of dexamethasone
64. +)-ATPase alpha subunit isoforms in articular chondrocytes
65. The calcium pumping ATPase of the plasma membrane
66. Molecular cloning of a plasma membrane calcium pump from human osteoblasts
67. Osteoblasts express the PMCA1b isoform of the plasma membrane Ca-ATPase
68. Comparison of the substrate dependence properties of the rat Na,K-ATPase α1, α2, and α3 isoforms expressed in HeLa cells
69. Demonstration of sodium/calcium exchange in rodent osteoblasts
70. Na-Ca exchange in rat osteoblast-like UMR 106 cells
71. + exchanger in a rat bone cell line: Temperature dependence and activation pathways
72. +-ATPase by insulin: Why and how
73. + pump in clonal rat osteosarcoma cells
74. A prospective study of bone mass in patients with type I diabetes
75. Effects of diabetes mellitus on bone mass in juvenile and adult-onset diabetes
76. Characterization of the effect of insulin on collagen synthesis in fetal rat bone
77. Gastric adenosine triphosphatases: A review of their possible role in HCl secretion
78. +-ATPase in the kidney: Localization and function in the nephron
79. The mechanism and structure of the gastric H/K-ATPase
80. Does the colonic H,K-ATPase also act as an Na,K-ATPase
81. +-ATPase: Targeting signals in the regulation of physiologic function
82. Proton pump inhibitors and acid-related diseases
83. Humoral and ionic regulation of osteoclast acidity
84. Cell-mediated extracellular acidification and bone resorption: Evidence for a low pH in resorbing lacunae and localization of a 100 kDa lysosomal membrane protein at the osteoclast ruffled border
85. Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts
86. +-ATPase, inhibits bone resorption in vitro
87. +-ATPase, on bone resorption in humans
88. Inhibition of bone resorption by H,K-ATPase inhibitors
89. +-translocating ATPases
90. Osteoclastic bone resorption by a polarized vacuolar proton pump
91. +-ATPase type in the ruffled borders of osteoclasts
92. +)-ATPases
93. Vacuolar H-ATPases. Targets for drug discovery
94. Synthesis and structure-activity relationships of bafilomycin A1 derivatives as inhibitors of vacuolar H-ATPase
95. Characterization of ATP-dependent proton transport in medullary bone-derived microsomes
96. - anion exchanger (erythrocyte band-3 protein) in avian osteoclasts: Effect of calcium-deficient diet on polar expression of the H-ATPase pump
97. Proton channel part of vacuolar H-ATPase and carbonic anhydrase II expression is stimulated in resorbing osteoclasts
98. Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts
99. Isolation and reconstitution of a vacuolar-type proton pump of osteoclast membranes
100. Osteoclast molecular phenotyping by random cDNA sequencing
101. Passive chloride permeability charge coupled to H-ATPase of avian osteoclast ruffled membrane
102. Inhibition of bone resorption in vitro by antisense RNA and DNA molecules targeted against carbonic anhydrase II or two subunits of vacuolar H-ATPase
103. Inhibition of osteoclast proton transport by bafilomycin A1 abolishes bone resorption
104. +-ATPses
105. + ATPases
106. Molecular cloning and characterization of a putative novel human osteoclast-specific 116 kDa vacuolar proton pump subunit
107. The putative 116 kDa osteoclast specific vacuolar proton pump subunit has ubiquitous tissue distribution
108. Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification
109. Regulation of sodium-dependent phosphate transport in osteoclasts
110. + pumps in intracellular pH regulation in neonatal rat osteoclasts
111. The regulation of pHi in osteoclasts is dependent on the culture substrate and on the stage of the resorption cycle
112. Regulation of cytoplasmic pH in osteoclasts. Contribution of proton pumps and a proton-selective conductance
113. + ATPase activity in osteoclasts
114. Effect of pH on bone resorption by rat osteoclasts in vitro
115. Effect of medium pH on osteoclast activity and osteoclast formation in cultures of dispersed rabbit osteoclasts
116. Differences in regulation of pH(i) in large (≥10 nuclei) and small (≤5 nuclei) osteoclasts
117. Acid extrusion is induced by osteoclast attachment to bone. Inhibition by alendronate and calcitonin
118. Mutations in the a3 subunit of the vacuolar H(+)-ATPase cause infantile malignant osteopetrosis
119. Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man
120. Cytotoxicity of vacuolar H(+)-ATPase inhibitors to UMR-106 rat osteoblasts: An effect on iron uptake into cells
121. Inositol triphosphate and calcium signalling
122. 2+ adenosine triphosphatase pump recognize an epitope in the basolateral membrane of human kidney distal tubule cells
123. Plasma membrane calcium pump and 28 kDa calcium binding protein in cells of rat kidney distal tubules
124. 2+)-ATPase in isolated bone cells
125. 2+)-ATPase system in the osteoblast plasma membrane
126. 2+-ATPase pump in human osteoblast-like cell plasma membranes
127. Widespread distribution of calcium pump in calcium transporting tissues. Immunohistochemical studies
128. Plasma membrane Ca-pumping ATPases
129. +-Ca exchange in osteoblast-like cells
130. 2+-ATPase) in chick tibia
131. Characterization of a Ca-ATPase in osteoclast plasma membrane
132. Demonstration of calmodulin-sensitive calcium translocation by isolated osteoclast plasma membrane vesicles
133. An Arg-Gly-Asp peptide stimulates Ca efflux from osteoclast precursors through a novel mechanism
134. Identification of avian sarcoplasmic reticulum Ca-ATPase (SERCA3) as a novel 1,25(OH)2D3 target gene in the monocytic lineage
135. Ca-ATPase inhibitors and Ca-ionophore induce osteoclast-like cell formation in the co-cultures of mouse bone marrow cells and calvarial cells
136. Characterization of the functional stages of osteoclasts by enzyme histochemistry and electron microscopy
137. Characterization of calcium translocation across the plasma membrane of primary osteoblasts using a lipophilic calcium-sensitive fluorescent dye, calcium green C18
138. Asymmetric distribution of functional sodium-calcium exchanger in primary osteoblasts
139. Characterization of calcium efflux by osteoblasts derived from long bone periosteum
140. Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor
141. Evidence for P2-purinoceptors on human osteoblast-like cells
142. 2+ mobilization is strongly potentiated by a parathyroid hormone/cAMP-dependent protein kinase pathway independently of mitogen-activated protein kinase
143. Osteoblastic differentiation and p-glycoprotein multidrug resistance in a murine osteosarcoma model
144. p-Glycoprotein is expressed in the mineralizing regions of the skeleton
145. Identification of two subunit A isoforms of the vacuolar H(+)-ATPase in human osteoclastoma
146. Specific inhibitors of vacuolar H(+)-ATPase trigger apoptotic cell death of osteoclasts