The use of novel C-methylated spermidine derivatives to investigate the regulation of polyamine metabolism

Journal of Medicinal Chemistry

Volumn 54, Issue 13, 2011, Pages 4611-4618

  Hyvönen, Mervi T ^a   Keinänen, Tuomo A ^a   Khomutov, Maxim ^b   Simonian, Alina ^b   Weisell, Janne ^a   Kochetkov, Sergey N ^b   Vepsäläinen, Jouko ^a   Alhonen, Leena ^a   Khomutov, Alex R ^b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLSPERMIDINE; 2 METHYLSPERMIDINE; 3 METHYLSPERMIDINE; 8 METHYLSPERMIDINE; ACETYLPOLYAMINE OXIDASE; ACYLTRANSFERASE; EFLORNITHINE; MESSENGER RNA; ORNITHINE DECARBOXYLASE; OXIDOREDUCTASE; POLYAMINE; SPERMIDINE DERIVATIVE; SPERMINE N 1 ACETYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATABOLISM; CELL CYCLE ARREST; CELL GROWTH; CYTOTOXICITY; DOWN REGULATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; METHYLATION; MOUSE; NONHUMAN; POLYAMINE METABOLISM;

ACETYLTRANSFERASES; ALTERNATIVE SPLICING; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; EFLORNITHINE; HUMANS; MICE; ORNITHINE DECARBOXYLASE; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYAMINES; RECOMBINANT PROTEINS; RNA PRECURSORS; RNA, MESSENGER; SPERMIDINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960181862     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200293r     Document Type: Article

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