Synthesis and biological characterization of novel charge-deficient spermine analogues

Journal of Medicinal Chemistry

Volumn 53, Issue 15, 2010, Pages 5738-5748

  Weisell, Janne ^a   Hyvönen, Mervi T ^a   Häkkinen, Merja R ^a   Grigorenko, Nikolay A ^b   Pietilä, Marko ^a   Lampinen, Anita ^a   Kochetkov, Sergey N ^c   Alhonen, Leena ^a   Vepsäläinen, Jouko ^a   Keinänen, Tuomo A ^a   Khomutov, Alex R ^c  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b CIBA GEIGY LTD   (Switzerland)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

1,12 DIAMINO 3,6,9 TRIAZADODECANE; N1 ACETYL 1,12 DIAMINO 3,6,9 TRIAZADODECANE; N1,N11 DIETHYLNORSPERMINE; N1,N12 DIETHYL 1,12 DIAMINO 3,6,9 TRIAZADODECANE; N12 ACETYL 1,12 DIAMINO 3,6,9 TRIAZADODECANE; ORNITHINE DECARBOXYLASE; POLYAMINE DERIVATIVE; PUTRESCINE; SPERMIDINE; SPERMINE; SPERMINE DERIVATIVE; TRIENTINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG INDICATION; DRUG SYNTHESIS; ENZYME REGULATION; HUMAN; HUMAN CELL; WILSON DISEASE;

ACETYLTRANSFERASES; ALTERNATIVE SPLICING; ANIMALS; BIOGENIC POLYAMINES; CELL LINE, TUMOR; CELL PROLIFERATION; FIBROBLASTS; HUMANS; KINETICS; MICE; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; RECOMBINANT PROTEINS; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 77955358041     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100439p     Document Type: Article

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