The crystal structure of spermidine/spermine N1- acetyltransferase in complex with spermine provides insights into substrate binding and catalysis

Biochemistry

Volumn 47, Issue 35, 2008, Pages 9145-9153

  Montemayor, Eric J ^a   Hoffman, David W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE;

ASPARAGINE DERIVATIVE; COENZYME A; GLUTAMINE DERIVATIVE; SPERMIDINE; SPERMINE DERIVATIVE; SPERMINE N1 ACETYLTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SUBSTRATE COMPLEX; MOLECULE; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS;

ACETYL COENZYME A; ACETYLTRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HYDROGEN-ION CONCENTRATION; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SPERMIDINE; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 50849141905     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8009357     Document Type: Article

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