메뉴 건너뛰기




Volumn 290, Issue 1-2, 2010, Pages 123-130

Gene therapy using lactoferrin-modified nanoparticles in a rotenone-induced chronic Parkinson model

Author keywords

Brain gene therapy; Lactoferrin modified nanoparticles; Multiple dosing administration; Parkinson's disease; Rotenone

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LACTOFERRIN; NANOPARTICLE; NEUROTRANSMITTER; ROTENONE;

EID: 74849115546     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.09.032     Document Type: Article
Times cited : (139)

References (27)
  • 1
    • 33847261478 scopus 로고    scopus 로고
    • Controlled delivery of glial cell line-derived neurotrophic factor by a single tetracycline-inducible AAV vector
    • Chtarto A., Yang X., Bockstael O., Melas C., Blum D., Lehtonen E., et al. Controlled delivery of glial cell line-derived neurotrophic factor by a single tetracycline-inducible AAV vector. Exp Neurol 204 1 (2007) 387-399
    • (2007) Exp Neurol , vol.204 , Issue.1 , pp. 387-399
    • Chtarto, A.1    Yang, X.2    Bockstael, O.3    Melas, C.4    Blum, D.5    Lehtonen, E.6
  • 2
    • 1942506065 scopus 로고    scopus 로고
    • Gene therapy of the brain: the trans-vascular approach
    • Schlachetzki F., Zhang Y., Boado R., and Pardridge W.M. Gene therapy of the brain: the trans-vascular approach. Neurology 62 8 (2004) 1275-1281
    • (2004) Neurology , vol.62 , Issue.8 , pp. 1275-1281
    • Schlachetzki, F.1    Zhang, Y.2    Boado, R.3    Pardridge, W.M.4
  • 3
    • 1342332987 scopus 로고    scopus 로고
    • Gene targeting in vivo with pegylated immunoliposomes
    • Pardridge W.M. Gene targeting in vivo with pegylated immunoliposomes. Methods Enzymol 373 (2003) 507-528
    • (2003) Methods Enzymol , vol.373 , pp. 507-528
    • Pardridge, W.M.1
  • 4
    • 35548959221 scopus 로고    scopus 로고
    • The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain
    • Huang R.Q., Ke W.L., Liu Y., Jiang C., and Pei Y.Y. The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain. Biomaterials 29 2 (2008) 238-246
    • (2008) Biomaterials , vol.29 , Issue.2 , pp. 238-246
    • Huang, R.Q.1    Ke, W.L.2    Liu, Y.3    Jiang, C.4    Pei, Y.Y.5
  • 5
    • 0036283426 scopus 로고    scopus 로고
    • Modeling Parkinson′s disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway
    • Deumens R., Blokland A., and Prickaerts J. Modeling Parkinson′s disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway. Exp Neurol 175 2 (2002) 303-317
    • (2002) Exp Neurol , vol.175 , Issue.2 , pp. 303-317
    • Deumens, R.1    Blokland, A.2    Prickaerts, J.3
  • 6
    • 33847254416 scopus 로고    scopus 로고
    • Dopaminergic neuroprotection by neurturin-expressing c17.2 neural stem cells in a rat model of Parkinson′s disease
    • Liu W.G., Lu G.Q., Li B., and Chen S.D. Dopaminergic neuroprotection by neurturin-expressing c17.2 neural stem cells in a rat model of Parkinson′s disease. Parkinsonism Relat Disord 13 2 (2007) 77-88
    • (2007) Parkinsonism Relat Disord , vol.13 , Issue.2 , pp. 77-88
    • Liu, W.G.1    Lu, G.Q.2    Li, B.3    Chen, S.D.4
  • 7
    • 26944477762 scopus 로고    scopus 로고
    • A delivery strategy for rotenone microspheres in an animal model of Parkinson′s disease
    • Huang J., Liu H., Gu W., Yan Z., Xu Z., Yang Y., et al. A delivery strategy for rotenone microspheres in an animal model of Parkinson′s disease. Biomaterials 27 6 (2006) 937-946
    • (2006) Biomaterials , vol.27 , Issue.6 , pp. 937-946
    • Huang, J.1    Liu, H.2    Gu, W.3    Yan, Z.4    Xu, Z.5    Yang, Y.6
  • 8
    • 34247464677 scopus 로고    scopus 로고
    • The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats
    • Samantaray S., Knaryan V.H., Guyton M.K., Matzelle D.D., Ray S.K., and Banik N.L. The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats. Neuroscience 146 2 (2007) 741-755
    • (2007) Neuroscience , vol.146 , Issue.2 , pp. 741-755
    • Samantaray, S.1    Knaryan, V.H.2    Guyton, M.K.3    Matzelle, D.D.4    Ray, S.K.5    Banik, N.L.6
  • 9
    • 0037126181 scopus 로고    scopus 로고
    • Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats
    • Alam M., and Schmidt W.J. Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats. Behav Brain Res 136 1 (2002) 317-324
    • (2002) Behav Brain Res , vol.136 , Issue.1 , pp. 317-324
    • Alam, M.1    Schmidt, W.J.2
  • 10
    • 0037402801 scopus 로고    scopus 로고
    • Selective microglial activation in the rat rotenone model of Parkinson′s disease
    • Sherer T.B., Betarbet R., Kim J.H., and Greenamyre J.T. Selective microglial activation in the rat rotenone model of Parkinson′s disease. Neurosci Lett 341 2 (2003) 87-90
    • (2003) Neurosci Lett , vol.341 , Issue.2 , pp. 87-90
    • Sherer, T.B.1    Betarbet, R.2    Kim, J.H.3    Greenamyre, J.T.4
  • 12
    • 22144431587 scopus 로고    scopus 로고
    • Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion
    • Sindhu K.M., Saravanan K.S., and Mohanakumar K.P. Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion. Brain Res 1051 1-2 (2005) 25-34
    • (2005) Brain Res , vol.1051 , Issue.1-2 , pp. 25-34
    • Sindhu, K.M.1    Saravanan, K.S.2    Mohanakumar, K.P.3
  • 14
    • 46949110191 scopus 로고    scopus 로고
    • GDNF therapy for Parkinson′s disease
    • Hong M., Mukhida K., and Mendez I. GDNF therapy for Parkinson′s disease. Expert Rev Neurother 8 7 (2008) 1125-1139
    • (2008) Expert Rev Neurother , vol.8 , Issue.7 , pp. 1125-1139
    • Hong, M.1    Mukhida, K.2    Mendez, I.3
  • 15
    • 41249095549 scopus 로고    scopus 로고
    • Advances in gene therapy for movement disorders
    • Mochizuki H., Yasuda T., and Mouradian M.M. Advances in gene therapy for movement disorders. Neurotherapeutics 5 2 (2008) 260-269
    • (2008) Neurotherapeutics , vol.5 , Issue.2 , pp. 260-269
    • Mochizuki, H.1    Yasuda, T.2    Mouradian, M.M.3
  • 16
    • 0034721690 scopus 로고    scopus 로고
    • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson′s disease
    • Kordower J.H., Emborg M.E., Bloch J., Ma S.Y., Chu Y., Leventhal L., et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson′s disease. Science 290 5492 (2000) 767-773
    • (2000) Science , vol.290 , Issue.5492 , pp. 767-773
    • Kordower, J.H.1    Emborg, M.E.2    Bloch, J.3    Ma, S.Y.4    Chu, Y.5    Leventhal, L.6
  • 17
    • 33947625559 scopus 로고    scopus 로고
    • Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer
    • Huang R.Q., Qu Y.H., Ke W.L., Zhu J.H., Pei Y.Y., and Jiang C. Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. FASEB J 21 4 (2007) 1117-1125
    • (2007) FASEB J , vol.21 , Issue.4 , pp. 1117-1125
    • Huang, R.Q.1    Qu, Y.H.2    Ke, W.L.3    Zhu, J.H.4    Pei, Y.Y.5    Jiang, C.6
  • 18
    • 0037382337 scopus 로고    scopus 로고
    • Nicotine protects rat brain mitochondria against experimental injuries
    • Cormier A., Morin C., Zini R., Tillement J.P., and Lagrue G. Nicotine protects rat brain mitochondria against experimental injuries. Neuropharmacology 44 5 (2003) 642-652
    • (2003) Neuropharmacology , vol.44 , Issue.5 , pp. 642-652
    • Cormier, A.1    Morin, C.2    Zini, R.3    Tillement, J.P.4    Lagrue, G.5
  • 19
    • 33847675291 scopus 로고    scopus 로고
    • Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model
    • Saravanan K.S., Sindhu K.M., and Mohanakumar K.P. Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model. J Pineal Res 42 3 (2007) 247-253
    • (2007) J Pineal Res , vol.42 , Issue.3 , pp. 247-253
    • Saravanan, K.S.1    Sindhu, K.M.2    Mohanakumar, K.P.3
  • 20
    • 39049085707 scopus 로고    scopus 로고
    • Protection by the NDI1 gene against neurodegeneration in a rotenone rat model of Parkinson′s disease
    • Marella M., Seo B.B., Nakamaru-Ogiso E., Greenamyre J.T., Matsuno-Yagi A., and Yagi T. Protection by the NDI1 gene against neurodegeneration in a rotenone rat model of Parkinson′s disease. PLoS ONE 3 1 (2008) e1433
    • (2008) PLoS ONE , vol.3 , Issue.1
    • Marella, M.1    Seo, B.B.2    Nakamaru-Ogiso, E.3    Greenamyre, J.T.4    Matsuno-Yagi, A.5    Yagi, T.6
  • 21
    • 23944465946 scopus 로고    scopus 로고
    • Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury
    • da Cruz M.T., Cardoso A.L., de Almeida L.P., Simões S., and de Lima M.C. Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury. Gene Ther 12 16 (2005) 1242-1252
    • (2005) Gene Ther , vol.12 , Issue.16 , pp. 1242-1252
    • da Cruz, M.T.1    Cardoso, A.L.2    de Almeida, L.P.3    Simões, S.4    de Lima, M.C.5
  • 22
    • 40549111959 scopus 로고    scopus 로고
    • Intravenous glial-derived neurotrophic factor gene therapy of experimental Parkinson′s disease with Trojan horse liposomes and a tyrosine hydroxylase promoter
    • Xia C.F., Boado R.J., Zhang Y., Chu C., and Pardridge W.M. Intravenous glial-derived neurotrophic factor gene therapy of experimental Parkinson′s disease with Trojan horse liposomes and a tyrosine hydroxylase promoter. J Gene Med 10 3 (2008) 306-315
    • (2008) J Gene Med , vol.10 , Issue.3 , pp. 306-315
    • Xia, C.F.1    Boado, R.J.2    Zhang, Y.3    Chu, C.4    Pardridge, W.M.5
  • 23
    • 0028786932 scopus 로고
    • Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson disease
    • Faucheux B.A., Nillesse N., Damier P., Spik G., Mouatt-Prigent A., Pierce A., et al. Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson disease. Proc Natl Acad Sci U S A 92 21 (1995) 9603-9607
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.21 , pp. 9603-9607
    • Faucheux, B.A.1    Nillesse, N.2    Damier, P.3    Spik, G.4    Mouatt-Prigent, A.5    Pierce, A.6
  • 24
    • 70349501374 scopus 로고    scopus 로고
    • Neuroprotection in a 6-OHDA-lesioned Parkinson model using lactoferrin-modified nanoparticles
    • Huang R.Q., Han L., Li J.H., Ren F.L., Ke W.L., Jiang C., and Pei Y.Y. Neuroprotection in a 6-OHDA-lesioned Parkinson model using lactoferrin-modified nanoparticles. J Gene Med 11 9 (2009) 754-763
    • (2009) J Gene Med , vol.11 , Issue.9 , pp. 754-763
    • Huang, R.Q.1    Han, L.2    Li, J.H.3    Ren, F.L.4    Ke, W.L.5    Jiang, C.6    Pei, Y.Y.7
  • 25
    • 0141788689 scopus 로고    scopus 로고
    • Protective effects of intracerebral adenoviral-mediated GDNF gene transfer in a rat model of Parkinson′s disease
    • Chen X., Liu W., Guoyuan Y., Liu Z., Smith S., Calne D.B., et al. Protective effects of intracerebral adenoviral-mediated GDNF gene transfer in a rat model of Parkinson′s disease. Parkinsonism Relat Disord 10 1 (2003) 1-7
    • (2003) Parkinsonism Relat Disord , vol.10 , Issue.1 , pp. 1-7
    • Chen, X.1    Liu, W.2    Guoyuan, Y.3    Liu, Z.4    Smith, S.5    Calne, D.B.6
  • 26
    • 63949084137 scopus 로고    scopus 로고
    • Near complete rescue of experimental Parkinson′s disease with intravenous, non-viral GDNF gene therapy
    • Zhang Y., and Pardridge W.M. Near complete rescue of experimental Parkinson′s disease with intravenous, non-viral GDNF gene therapy. Pharm Res 26 5 (2009) 1059-1063
    • (2009) Pharm Res , vol.26 , Issue.5 , pp. 1059-1063
    • Zhang, Y.1    Pardridge, W.M.2
  • 27
    • 77049097886 scopus 로고    scopus 로고
    • Pedersen LM, Jacobsen LM, Mollerup S, G jerstad J. Spinal cord long-termpotentiation (LTP) is associated with increased dorsal horn gene expression of IL-1beta, GDNF and iNOS. Eur J Pain in press, doi:10.1016/j.ejpain.2009.05.016.
    • Pedersen LM, Jacobsen LM, Mollerup S, G jerstad J. Spinal cord long-termpotentiation (LTP) is associated with increased dorsal horn gene expression of IL-1beta, GDNF and iNOS. Eur J Pain in press, doi:10.1016/j.ejpain.2009.05.016.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.