A MyD88-dependent IFNγR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge

Cell Research

Volumn 21, Issue 7, 2011, Pages 1068-1079

  Pietras, Eric M ^a   Miller, Lloyd S ^a   Johnson, Carl T ^a   O'Connell, Ryan M ^a   Dempsey, Paul W ^a,c   Cheng, Genhong ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CytomX LLC   (United States)

Author keywords

bacteria; chemokine; infection; interferon; monocyte

Indexed keywords

CCL2 PROTEIN, MOUSE; CCR2 PROTEIN, MOUSE; CHEMOKINE RECEPTOR CCR2; GAMMA INTERFERON RECEPTOR; INTERFERON RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOID DIFFERENTIATION FACTOR 88;

ANIMAL; ARTICLE; CYTOLOGY; FRANCISELLA TULARENSIS; GENE DELETION; GENE EXPRESSION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INNATE IMMUNITY; MICROBIOLOGY; MONOCYTE; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPLEEN; TULAREMIA;

ANIMALS; CHEMOKINE CCL2; FRANCISELLA TULARENSIS; GENE DELETION; GENE EXPRESSION; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; MICE; MONOCYTES; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, CCR2; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; SPLEEN; TULAREMIA;

BACTERIA (MICROORGANISMS); FRANCISELLA TULARENSIS; MUS;

EID: 79960146004     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2011.59     Document Type: Article

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