Qualitative and Quantitative Analysis of Glycated Proteins in Human Plasma by Glucose Isotopic Labeling with13C6-Reducing Sugars

Methods in Molecular Biology

Volumn 728, Issue , 2011, Pages 219-232

  Priego Capote, Feliciano ^b   Ramírez Boo, Maria ^b   Hochstrasser, Denis ^b   Sanchez, Jean Charles ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b NONE

Author keywords

Glucotoxicity; Isotopic labeling; Mass spectrometry; Plasma proteomics; Protein glycation

Indexed keywords

BORONIC ACID DERIVATIVE; CARBON; GLUCOSE; GLUTAMYL ENDOPEPTIDASE; GLYCOPEPTIDE; GLYCOPROTEIN; PLASMA PROTEIN; SERINE PROTEINASE;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ARTICLE; BLOOD; BLOOD SAMPLING; CARBOHYDRATE METABOLISM; CHEMISTRY; GLYCOSYLATION; HUMAN; ISOLATION AND PURIFICATION; ISOTOPE LABELING; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION;

AMINO ACID SEQUENCE; BLOOD PROTEINS; BLOOD SPECIMEN COLLECTION; BORONIC ACIDS; CARBOHYDRATE METABOLISM; CARBON ISOTOPES; CHROMATOGRAPHY, AFFINITY; GLUCOSE; GLYCOPEPTIDES; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; ISOTOPE LABELING; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; SERINE ENDOPEPTIDASES;

EID: 79960144695     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61779-068-3_14     Document Type: Chapter

References (22)

1. Costello CE, Contado-Miller J M, Cipollo JF (2007) A glycomics platform for the analysis of permethylated oligosaccharide alditols. J Am Soc Mass Spectrom 18, 1799–1812.
2. Maillard L C (1912) Action des acides amines sur le sucres: formation des mélanoidines per voie méthodique. C R Acad Sci 154, 66–68.
3. Thornalley P J, Langborg A, Minhas H S (1999) Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose. Biochem J 344, 109–116.
4. Brock J W C, Hinton D J S, Cotham W E, et al. (2003) Proteomic analysis of the site specificity of glycation and carboxymethyla-tion of ribonuclease. J Proteome Res 2, 506–513.
5. Brunner Y, Schvartz D, Priego-Capote F, et al. (2009) Glucotoxicity and pancreatic proteomics. J Proteomics 71, 576–591.
6. Reusch J E (2003) Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose? J Clin Invest 112, 986–988.
7. Baynes J W (2001) The role of AGEs in aging: causation or correlation. Exp Gerontol 36, 1527–1537.
8. Brownlee M (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 14, 813–820.
9. Hipkiss A R (2006) Accumulation of altered proteins and ageing: causes and effects. Exper Gerontol 41, 464–473.
10. Calvo C, Ponsin G, Berthezene F (1998) Characterization of the nonenzymatic glycation of high-density lipoprotein in diabetic patients. Diabete Metab 14, 264–269.
11. Calvo C, Talussot C, Ponsin G, Berthezene F (1988) Nonenzymatic glycation of apolipoprotein A-I. Effects on its self-association and lipid binding properties. Biochem Biophys Res Comm 153, 1060–1067.
12. Calvo C, Verdugo C (1992) Association in vivo of glycated apolipoprotein A-I with high density lipoproteins. Eur J Clin Chem Clin Biochem 30, 3–5.
13. Abdel-Wahab Y H A, O’Harte F P M, Boyd A C, et al. (1997) Glycation of insulin results in reduced biological activity in mice. Acta Diabetol 34, 265–270.
14. 1 c determination. Diabetologia 47, 1143–1148.
15. Ladyzynski P, Wojcicki J M, Bak M. et al. (2008) Validation of haemoglobin glycation models using glycemia monitoring in vivo and culturing of erythrocytes in vitro. Ann Biomed Eng 36, 1188–1202.
16. Saudek C D, Derr R L, Kalyani R R (2006) Assessing glycemica in diabetes using self-monitoring blood glucose and hemoglobin A1c. J Am Med Assoc 295, 1688–1697.
17. Brownlee M, Hirsch I B (2006) Glycemic variability: a hemoglobin A1c-independent risk factor for diabetic complications. J Am Med Assoc 295, 1707–1708.
18. Kisugi R, Kouzuma T, Yamamoto T. et al. (2007) Structural and glycation site changes of albumin in diabetic patient with very high glycated albumin. Clin Chim Acta 382, 59–64.
19. Yoshiuchi K, Matsuhisa M, Katakami N. et al. (2008) Glycated albumin is a better indicator for glucose excursion than glycated hemoglobin in type 1 and type 2 diabetes. Endocrine J 55, 503–507.
20. 3 C-reducing sugars for quantitative analysis of glycated proteins in human plasma. Mol Cell Proteomics 9, 579–592.
21. Bradford M (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248–254.
22. Huttlin E L, Hegeman A D, Harms A C, Sussman M R (2007) Prediction of error associated with false-positive rate determination for peptide identification in large-scale proteomics experiments using a combined reverse and forward peptide sequence database strategy. J Prot Res 6, 392–398.