In utero exposure to the antiandrogen di-(2-ethylhexyl) phthalate decreases adrenal aldosterone production in the adult rat

Biology of Reproduction

Volumn 85, Issue 1, 2011, Pages 51-61

  Martinez Arguelles, Daniel B ^a,b   Guichard, Theodore ^b   Culty, Martine ^a,b,c   Zirkin, Barry R ^d   Papadopoulos, Vassilios ^a,b,c  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Adrenal cortex; Endocrine disruptors; Leydig cells; Phthalates; Steroid hormones steroid hormone receptors; Testosterone formation; Toxicology

Indexed keywords

ALDOSTERONE SYNTHASE; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; CORTICOSTERONE; CORTICOTROPIN; MESSENGER RNA; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; POTASSIUM; TESTOSTERONE;

ALDOSTERONE BLOOD LEVEL; ALDOSTERONE RELEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; FEMALE; GESTATION PERIOD; LEYDIG CELL; MALE; NONHUMAN; PERINATAL PERIOD; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPRAGUE DAWLEY RAT; TESTOSTERONE SYNTHESIS;

ADRENAL GLANDS; ALDOSTERONE; ALDOSTERONE SYNTHASE; ANIMALS; DIETHYLHEXYL PHTHALATE; FEMALE; LEYDIG CELLS; MALE; MATERNAL EXPOSURE; PLASTICIZERS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANGIOTENSIN; RECEPTORS, MINERALOCORTICOID; UP-REGULATION;

RATTUS;

EID: 79960135412     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.110.089920     Document Type: Article

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