Chemodivergent synthesis of 7-aryl/alkyl-6-hydroxy-1,4-oxazepan-5-ones and 2-[aryl/alkyl(hydroxy)methyl]morpholin-3-ones from a common epoxyamide precursor

Synthesis

Volumn , Issue 14, 2011, Pages 2310-2320

  Aparicio, David M ^a   Terán, Joel L ^a   Roa, Luis F ^b   Gnecco, Dino ^a   Juárez, Jorge R ^a   Orea, María L ^a   Mendoza, Angel ^a   Flores Alamo, Marcos ^c   Micouin, Laurent ^d  

^a BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

^b UNIVERSIDAD JUÁREZ AUTÓNOMA DE TABASCO   (Mexico)

^c Universidad Nacional Autonoma de Mexico Facultad de Quimica   (Mexico)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

alkoxide; chemoselectivity; cyclization; morpholin 3 ones; oxazepan 5 ones

Indexed keywords

ALKOXIDES; CARBOXAMIDES; CHEMOSELECTIVITY; CYCLIZATION REACTIONS; DIASTEREOMERIC; MORPHOLIN-3-ONES; OXAZEPAN-5-ONES; REGIOSPECIFIC SYNTHESIS;

SYNTHESIS (CHEMICAL);

CYCLIZATION;

2 (1 HYDROXYALKYL)MORPHOLIN 3 ONE DERIVATIVE; 2 [ARYL(HYDROXY)METHYL]MORPHOLIN 3 ONE DERIVATIVE; 3 ALKYL N (2 HYDROXYETHYL) N (1 PHENYLETHYL)OXIRANE 2 CARBOXAMIDE DERIVATIVE; 3 ARYL N (2 HYDROXYETHYL) N (1 PHENYLETHYL)OXIRANE 2 CARBOXAMIDE DERIVATIVE; 7 ALKYL 6 HYDROXY 1,4 OXAZEPAN 5 ONE DERIVATIVE; 7 ARYL 6 HYDROXY 1,4 OXAZEPAN 5 ONE DERIVATIVE; AMIDE; CHEMICAL COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHEMODIVERGENT SYNTHESIS; CYCLIZATION; STEREOMETRY; SYNTHESIS;

EID: 79960125856     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260064     Document Type: Article

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