Synthesis of single-enantiomer 6-hydroxy-7-phenyl-1,4-oxazepan-5-ones

Synthesis

Volumn , Issue 15, 2005, Pages 2549-2561

  Becker, Christopher W ^a   Dembofsky, Bruce T ^a   Hall, James E ^a   Jacobs, Robert T ^a   Pivonka, Don E ^a   Ohnmacht, Cyrus J ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Epoxides; Heterocycles; Magnesium; Ring closure; Scandium

Indexed keywords

CATALYSTS; DERIVATIVES; ESTERS; ETHANOL; MAGNESIUM PRINTING PLATES; SCANDIUM; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

ENANTIOMERS; EPOXIDES; HETEROCYCLES; RING CLOSURE;

KETONES;

3 PHENYLOXIRANE 2 CARBOXYLIC DERIVATIVE; 3 PHENYLOXIRANE 2 CARBOXYLIC ETHYL ESTER; 6 HYDROXY 7 PHENYL 1,4 OXAZEPAN 5 ONE DERIVATIVE; AMIDE; CARBOXYLIC ACID DERIVATIVE; EPOXIDE; EPOXYAMIDE DERIVATIVE; ESTER DERIVATIVE; ETHANOLAMINE DERIVATIVE; OXAZEPINE DERIVATIVE; PHENYL GROUP; POTASSIUM SALT; SCANDIUM; STYRENE OXIDE; UNCLASSIFIED DRUG;

ARTICLE; CATALYST; CHEMICAL REACTION; CHIRALITY; CYCLIZATION; DIASTEREOISOMER; ENANTIOMER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; REPRODUCIBILITY; RING CLOSING METATHESIS; STEREOCHEMISTRY; SYNTHESIS; TECHNIQUE;

EID: 26844494430     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-872122     Document Type: Article

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