Reprint of "nanobody - Shell functionalized thermosensitive core-crosslinked polymeric micelles for active drug targeting"

Journal of Controlled Release

Volumn 153, Issue 1, 2011, Pages 93-102

  Talelli, Marina ^a   Rijcken, Cristianne J F ^a   Oliveira, Sabrina ^b   Van Der Meel, Roy ^a   Van Bergen En Henegouwen, Paul M P ^b   Lammers, Twan ^a,c   Van Nostrum, Cornelus F ^a   Storm, Gert ^a   Hennink, Wim E ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Active targeting; anti EGFR nanobody; Biodegradable; Cancer therapy; Cellular uptake; Polymeric micelle

Indexed keywords

ACTIVE TARGETING; ANTI-EGFR; BIODEGRADABLE; CANCER THERAPY; CELLULAR UPTAKE; POLYMERIC MICELLE;

BIODEGRADABLE POLYMERS; BLOCK COPOLYMERS; CROSSLINKING; DISEASES; ENZYMES; ETHYLENE; FUNCTIONAL POLYMERS; GEL PERMEATION CHROMATOGRAPHY; GLYCOLS; MOTION PICTURE EXPERTS GROUP STANDARDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; SIZE EXCLUSION CHROMATOGRAPHY;

MICELLES;

ANTIBODY; COPOLYMER; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; LYSOZYME; NANOBODY; POLY(ETHYLENE GLYCOL) BETA POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDELACTATE]; RHODAMINE; UNCLASSIFIED DRUG; HYDROXYLAMINE; N SUCCINIMIDYL 3 (2 PYRIDYLDITHIO) PROPIONATE; N SUCCINIMIDYLACETYLTHIOACETATE; POLY(ETHYLENE GLYCOL) POLY[N (2 HYDROXYPROPYL) METHACRYLAMIDELACTATE]; POLYMER;

BIODEGRADABILITY; CONFERENCE PAPER; CROSS LINKING; DRUG SYNTHESIS; DRUG TARGETING; GEL PERMEATION CHROMATOGRAPHY; MICELLE; PRIORITY JOURNAL; ANIMAL CELL; BINDING AFFINITY; CONJUGATION; DOT HYBRIDIZATION; FLUORESCENCE ACTIVATED CELL SORTING; HEAT SENSITIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; WESTERN BLOTTING;

EID: 79960108777     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.06.003     Document Type: Conference Paper

References (57)

1. L. Bromberg Polymeric micelles in oral chemotherapy J. Control. Release 128 2008 99 112
2. G. Gaucher, R.H. Marchessault, and J.C. Leroux Polyester-based micelles and nanoparticles for the parenteral delivery of taxanes J. Control. Release 143 2010 2 12
3. K. Kataoka, G.S. Kwon, M. Yokoyama, T. Okano, and Y. Sakurai Block copolymer micelles as vehicles for drug delivery J. Control. Release 24 1993 119 132 (Pubitemid 23161325)
4. N. Nishiyama, and K. Kataoka Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery Pharmacol. Therapeut. 112 2006 630 648 (Pubitemid 44592613)
5. V.P. Torchilin Micellar nanocarriers: pharmaceutical perspectives Pharm. Res. 24 2007 1 16 (Pubitemid 44902565)
6. Y. Bae, and K. Kataoka Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers Adv. Drug Deliver. Rev. 61 2009 768 784
7. A. Mahmud, X.B. Xiong, H.M. Aliabadi, and A. Lavasanifar Polymeric micelles for drug targeting J. Drug Target. 15 2007 553 584 (Pubitemid 350031081)
8. C. Oerlemans, W. Bult, M. Bos, G. Storm, J.F.W. Nijsen, and W.E. Hennink Polymeric micelles in anticancer therapy: targeting, imaging and triggered release Pharm. Res. 27 2010 2569 2589
9. X.B. Xiong, A. Mahmud, H. Uludag, and A. Lavasanifar Multifunctional polymeric micelles for enhanced intracellular delivery of doxorubicin to metastatic cancer cells Pharm. Res. 25 2008 2555 2566
10. S. Danson, D. Ferry, V. Alakhov, J. Margison, D. Kerr, D. Jowle, M. Brampton, G. Halbert, and M. Ranson Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer Brit. J. Cancer 90 2004 2085 2091 (Pubitemid 38869710)
11. R. Duncan The dawning era of polymer therapeutics Nat. Rev. Drug Discov. 2 2003 347 360 (Pubitemid 37361705)
12. Y. Matsumura, T. Hamaguchi, T. Ura, K. Muro, Y. Yamada, Y. Shimada, K. Shirao, T. Okusaka, H. Ueno, M. Ikeda, and N. Watanabe Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin Brit. J. Cancer 91 2004 1775 1781 (Pubitemid 39664964)
13. Y. Matsumura, and K. Kataoka Preclinical and clinical studies of anticancer agent-incorporating polymer micelles Cancer Sci. 100 2009 572 579
14. M. Yokoyama Polymeric micelles as a new drug carrier system and their required considerations for clinical trials Expert Opin. Drug Del. 7 2010 145 158
15. H. Maeda, J. Wu, T. Sawa, Y. Matsumura, and K. Hori Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review J. Control. Release 65 2000 271 284 (Pubitemid 30122932)
16. H. Maeda Tumor-selective delivery of macromolecular drugs via the EPR effect: background and future prospects Bioconjug. Chem. 21 2010 797 802
17. M. Talelli, C.J.F. Rijcken, C.F. van Nostrum, G. Storm, and W.E. Hennink Micelles based on HPMA copolymers Adv. Drug Deliver. Rev. 62 2010 231 239
18. C.F. Van Nostrum, D. Neradovic, O. Soga, and W.E. Hennink Polymeric micelles with transient stability: a novel delivery concept ACS Sym. Ser. 2006 40 54
19. C.J.F. Rijcken, T.F.J. Veldhuis, A. Ramzi, J.D. Meeldijk, C. van Nostrum, and W.E. Hennink Novel fast degradable thermosensitive polymeric micelles based on PEG-block-poly(N-(2-hydroxyethyl)methacrylamide-oligolactates) Biomacromolecules 6 2005 2343 2351 (Pubitemid 41052235)
20. O. Soga, C.F. Van Nostrum, A. Ramzi, T. Visser, F. Soulimani, P.M. Frederik, P.H.H. Bomans, and W.E. Hennink Physicochemical characterization of degradable thermosensitive polymeric micelles Langmuir 20 2004 9388 9395
21. C.J.F. Rijcken, J.W. Hofman, F. van Zeeland, W.E. Hennink, and C.F. van Nostrum Photosensitiser-loaded biodegradable polymeric micelles: preparation, characterisation and in vitro PDT efficacy J. Control. Release 124 2007 144 153 (Pubitemid 350101885)
22. O. Soga, C.F. Van Nostrum, M. Fens, C.J.F. Rijcken, R.M. Schiffelers, G. Storm, and W.E. Hennink Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery J. Control. Release 103 2005 341 353 (Pubitemid 40342534)
23. M. Talelli, C.J.F. Rijcken, T. Lammers, P.R. Seevinck, G. Storm, C.F. Van Nostrum, and W.E. Hennink Superparamagnetic iron oxide nanoparticles encapsulated in biodegradable thermosensitive polymeric micelles: toward a targeted nanomedicine suitable for image-guided drug delivery Langmuir 25 2009 2060 2067
24. P.M. van Hasselt, G.E.P.J. Janssens, T.K. Slot, M. van der Ham, T.C. Minderhoud, M. Talelli, L.M. Akkermans, C.J.F. Rijcken, and C.F. van Nostrum The influence of bile acids on the oral bioavailability of vitamin K encapsulated in polymeric micelles J. Control. Release 133 2009 161 168
25. M. Talelli, M. Iman, A.K. Varkouhi, C.J.F. Rijcken, R.M. Schiffelers, T. Etrych, K. Ulbrich, C.F. van Nostrum, T. Lammers, G. Storm, and W.E. Hennink Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin Biomaterials 31 2010 7797 7804
26. D. Neradovic, M.J. Van Steenbergen, L. Vansteelant, Y.J. Meijer, C.F. Van Nostrum, and W.E. Hennink Degradation mechanism and kinetics of thermosensitive polyacrylamides containing lactic acid side chains Macromolecules 36 2003 7491 7498
27. C.J.F. Rijcken, O. Soga, W.E. Hennink, and C.F.v. Nostrum Triggered destabilisation of polymeric micelles and vesicles by changing polymers polarity: an attractive tool for drug delivery J. Control. Release 120 2007 131 148 (Pubitemid 47058635)
28. C.J. Rijcken, C.J. Snel, R.M. Schiffelers, C.F. van Nostrum, and W.E. Hennink Hydrolysable core-crosslinked thermosensitive polymeric micelles: synthesis, characterisation and in vivo studies Biomaterials 28 2007 5581 5593 (Pubitemid 47599643)
29. M. Ferrari Cancer nanotechnology: opportunities and challenges Nat. Rev. Cancer 5 2005 161 171 (Pubitemid 40314948)
30. V.P. Torchilin Drug targeting Eur. J. Pharm. Sci. 11 2000 S81 S91
31. V.P. Torchilin Multifunctional nanocarriers Adv. Drug Deliver. Rev. 58 2006 1532 1555 (Pubitemid 44822608)
32. Z. Liu, Z. Yu, W. He, S. Ma, L. Sun, and F. Wang In-vitro internalization and in-vivo tumor uptake of anti-EGFR monoclonal antibody LA22 in A549 lung cancer cells and animal model Cancer Biother. Radio. 24 2009 15 23
33. T. Lammers, W.E. Hennink, and G. Storm Tumour-targeted nanomedicines: principles and practice Brit. J. Cancer 99 2008 392 397
34. F. Marcucci, and F. Lefoulon Active targeting with particulate drug carriers in tumor therapy: fundamentals and recent progress Drug Discov. Today 9 2004 219 228 (Pubitemid 38230021)
35. K. Petrak Essential properties of drug-targeting delivery systems Drug Discov. Today 10 2005 1667 1673 (Pubitemid 41817615)
36. S. Oliveira, R.M. Schiffelers, J. van der Veeken, R. van der Meel, R. Vongpromek, P.M.P. van Bergen en Henegouwen, G. Storm, and R.C. Roovers Downregulation of EGFR by a novel multivalent nanobody-liposome platform J. Control. Release 145 2010 165 175
37. T. Noh, Y.H. Kook, C. Park, H. Youn, H. Kim, E.T. Oh, E.K. Choi, H.J. Park, and C. Kim Block copolymer micelles conjugated with anti-EGFR antibody for targeted delivery of anticancer drug J. Polym. Sci. A1 46 2008 7321 7331
38. C. Liao, Q. Sun, B. Liang, J. Shen, X. Shuai, Targeting EGFR-overexpressing tumor cells using Cetuximab-immunomicelles loaded with doxorubicin and superparamagnetic iron oxide, Eur. J. Radiol (2010) in press.
39. T.M. Allen Ligand-targeted therapeutics in anticancer therapy Nat. Rev. Cancer 2 2002 750 763 (Pubitemid 37328910)
40. C. Hamers-Casterman, T. Atarhouch, S. Muyldermans, G. Robinson, C. Hamers, E.B. Songa, N. Bendahman, and R. Hamers Naturally occurring antibodies devoid of light chains Nature 363 1993 446 448 (Pubitemid 23179389)
41. S. Muyldermans, T. Atarhouch, J. Saldanha, J. Barbosa, and R. Hamers Sequence and structure of V-H domain from naturally-occurring camel heavy-chain immunoglobulins lacking light-chains Protein Eng. 7 1994 1129 1135 (Pubitemid 24282500)
42. E. Dolk, C. Van Vliet, J.M.J. Perez, G. Vriend, H. Darbon, G. Ferrat, C. Cambillau, L.G.J. Frenken, and T. Verrips Induced refolding of a temperature denatured llama heavy-chain antibody fragment by its antigen Proteins 59 2005 555 564 (Pubitemid 40594299)
43. E.G. Hofman, M.O. Ruonala, A.N. Bader, D. van den Heuvel, J. Voortman, R.C. Roovers, A.J. Verkleij, H.C. Gerritsen, and P.M.P. van Bergen en Henegouwen EGF induces coalescence of different lipid rafts J. Cell Sci. 121 2008 2519 2528
44. J.S. Moore, and S.I. Stupp Room temperature polyesterification Macromolecules 23 1990 65 70
45. G.T. Hermanson Bioconjugate techniques 2008 Academic press San Diego, California 76 77
46. D. Neradovic, C.F. Van Nostrum, and W.E. Hennink Thermoresponsive polymeric micelles with controlled instability based on hydrolytically sensitive N-isopropylacrylamide copolymers Macromolecules 34 2001 7589 7591 (Pubitemid 33074518)
47. J. Loccufier, M. Van Bos, and E. Schacht Convenient method for the analysis of primary and secondary hydroxyl end groups in polyethers Polym. Bull. 27 1991 201 204
48. H. Du, R.C.A. Fuh, J. Li, L.A. Corkan, and J.S. Lindsey PhotochemCAD++: a computer-aided design and research tool in photochemistry Photochem. Photobiol. 68 1998 141 142 (Pubitemid 128472001)
49. D. Neradovic, O. Soga, C.F. Van Nostrum, and W.E. Hennink The effect of the processing and formulation parameters on the size of nanoparticles based on block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide) with and without hydrolytically sensitive groups Biomaterials 25 2004 2409 2418 (Pubitemid 38102394)
50. R.J.S. Duncan, P.I. Weston, and R. Wrigglesworth A new reagent which may be used to introduce sulfhydryl groups into proteins, and its use in the preparation of conjugates for immunoassay Anal. Biochem. 132 1983 68 73 (Pubitemid 13030992)
51. E. Verheyen, L. Delain-Bioton, S. van der Wal, N. el Morabit, A. Barendregt, W.E. Hennink, and C.F. van Nostrum Conjugation of methacrylamide groups to a model protein via a reducible linker for immobilization and subsequent triggered release from hydrogels Macromol. Biosci. 10 2010 1517 1526
52. G.T. Hermanson Bioconjugate techniques 2008 Academic press San Diego, California 112 113
53. D.M. Bollag, M.D. Rozycki, and S.J. Edelstein Protein Methods 1996 Wiley-Liss New York 107 172
54. A.M. Honegger, T.J. Dull, S. Felder, E. Van Obberghen, F. Bellot, D. Szapary, A. Schmidt, A. Ullrich, and J. Schlessinger Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing Cell 51 1987 199 209
55. F. Meng, W.E. Hennink, and Z. Zhong Reduction-sensitive polymers and bioconjugates for biomedical applications Biomaterials 30 2009 2180 2198
56. H. Bier, T. Hoffmann, I. Haas, and A. Van Lierop Anti-(epidermal growth factor) receptor monoclonal antibodies for the induction of antibody-dependent cell-mediated cytotoxicity against squamous cell carcinoma lines of the head and neck Cancer Immunol. Immun. 46 1998 167 173 (Pubitemid 28239882)
57. W. Ping Li, L.A. Meyer, D.A. Capretto, C.D. Sherman, and C.J. Anderson Receptor-binding, biodistribution, and metabolism studies of 64Cu-DOTA-cetuximab, a PET-imaging agent for epidermal growth-factor receptor-positive tumors Cancer Biother. Radio. 23 2008 158 171 (Pubitemid 351630188)