The effect of the processing and formulation parameters on the size of nanoparticles based on block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide) with and without hydrolytically sensitive groups

Biomaterials

Volumn 25, Issue 12, 2004, Pages 2409-2418

  Neradovic, D ^a   Soga, O ^a   Van Nostrum, C F ^a   Hennink, W E ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Heating rate; Nanoparticles; Poly(ethylene glycol); Poly(N isopropylacrylamide); Size control

Indexed keywords

HYDROLYSIS; HYDROPHILICITY; LIGHT SCATTERING; MOLECULAR WEIGHT; PARTICLE SIZE ANALYSIS; POLYETHYLENE GLYCOLS; POLYMERS;

CLOUD POINT (CP); FORMULATION PARAMETERS; THERMOSENSITIVE BLOCKS;

COPOLYMERS;

ACRYLIC ACID COPOLYMER; MACROGOL; MACROGOL 10000; MACROGOL 5000; NANOPARTICLE; PHOSPHATE; POLY(N ISOPROPYLACRYLAMIDE); SODIUM CHLORIDE; SOLVENT; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); DRUG FORMULATION; HYDROLYSIS; LIGHT SCATTERING; MOLECULAR WEIGHT; PRIORITY JOURNAL; TEMPERATURE;

EID: 0347760399     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2003.09.024     Document Type: Article

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