Controlled biodegradation of Self-assembling β-hairpin Peptide hydrogels by proteolysis with matrix metalloproteinase-13

Biomaterials

Volumn 32, Issue 27, 2011, Pages 6471-6477

  Giano, Michael C ^a,b   Pochan, Darrin J ^b   Schneider, Joel P ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

Author keywords

Biodegradation; Extracellular matrix; Hydrogel; Matrix metalloproteinase; Peptide; Self assembly

Indexed keywords

DEGRADATION PRODUCTS; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; EXTRACELLULAR MATRICES; IN-VITRO; MATERIAL DEGRADATION; MATRIX; MATRIX METALLOPROTEINASES; MATRIX-METALLOPROTEINASE-3; MIGRATION RATES; OSCILLATORY SHEAR RHEOLOGY; PEPTIDE HYDROGELS; PEPTIDE SEQUENCES; PRIMARY SEQUENCES; PROTEOLYTIC SUSCEPTIBILITY; SELF-ASSEMBLING; TISSUE INJURY;

BIODEGRADATION; DEGRADATION; ELECTROSPRAY IONIZATION; ENZYME ACTIVITY; ENZYME INHIBITION; GELS; MASS SPECTROMETRY; MICROBIOLOGY; PEPTIDES; SELF ASSEMBLY; SODIUM CHLORIDE; TISSUE;

HYDROGELS;

BETA HAIRPIN PEPTIDE; COLLAGENASE 3; PROTEIN DERIVATIVE; STROMELYSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BIODEGRADATION; CELL LINE; CELL MIGRATION; CELL STRAIN SW1353; ELECTROSPRAY MASS SPECTROMETRY; FLOW KINETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; TISSUE INJURY;

AMINO ACID SEQUENCE; BIODEGRADATION, ENVIRONMENTAL; CELL LINE, TUMOR; HUMANS; HYDROGELS; MATRIX METALLOPROTEINASE 13; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; RHEOLOGY;

EID: 79960080932     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.05.052     Document Type: Article

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