Solid-phase synthesis and kinetic characterization of fluorogenic enzyme-degradable hydrogel cross-linkers

Biomacromolecules

Volumn 7, Issue 4, 2006, Pages 1011-1016

  Moss, Jason A ^a,b   Stokols, Shula ^a   Hixon, Mark S ^a   Ashley, Fawn T ^a   Chang, Jason Y ^a   Janda, Kim D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b C S Bio Company   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL MODIFICATION; CROSSLINKING; DEGRADATION; ENZYME KINETICS; ENZYMES; HYDROGELS; SYNTHESIS (CHEMICAL);

FLUOROGENIC ENZYME-DEGRADABLE; HYDROGEL CROSS-LINKERS; HYDROGEL DEGRADATION; MATRIX METALLOPROTEASE (MMP); POLYPEPTIDE-DERIVED CROSS-LINKERS; SOLID-PHASE SYNTHESIS; SOLUTION-PHASE MODIFICATIONS;

POLYPEPTIDES;

ACRYLAMIDE DERIVATIVE; MATRIX METALLOPROTEINASE; N,N' METHYLENEBISACRYLAMIDE; POLYMER;

ARTICLE; BIODEGRADABILITY; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SPECIFICITY; FLUOROSCOPY; HYDROGEL; PEPTIDE SYNTHESIS; PHASE TRANSITION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN HYDROLYSIS; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; SOLID PHASE SYNTHESIS; STANDARDIZATION;

ACRYLAMIDES; HYDROGEL; KINETICS; MATRIX METALLOPROTEINASES; PEPTIDES;

EID: 33646371458     PISSN: 15257797     EISSN: None     Source Type: Journal    
DOI: 10.1021/bm051001s     Document Type: Article

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